PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID evm.model.supercontig_37.96
Organism
Carica papaya
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Caricaceae; Carica
Family MYB
Protein Properties Length: 266aa    MW: 30453.2 Da    PI: 6.9578
Description MYB family protein
Gene Model
Gene Model ID Type Source Coding Sequence
evm.model.supercontig_37.96genomeASGPBView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding43.38.4e-141055146
                                 TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHH CS
              Myb_DNA-binding  1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqk 46
                                 +g+W +eEde l++ v+++G+++W++I ++  + Rt+k+c++rw +
  evm.model.supercontig_37.96 10 KGPWKAEEDEVLINHVNKYGPRDWSSIRSKGLLQRTGKSCRLRWVN 55
                                 79*************************8887799**********87 PP
2Myb_DNA-binding445.2e-1466105344
                                  SS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHH CS
              Myb_DNA-binding   3 rWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrw 44 
                                  ++++eE+   +d+ +q+G++ W++Ia +++ gRt++++k++w
  evm.model.supercontig_37.96  66 KFSAEEERVVIDLQAQFGNK-WARIATYLP-GRTDNDVKNFW 105
                                  79******************.*********.*********** PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.602.0E-21558IPR009057Homeodomain-like
PROSITE profilePS5129421.291561IPR017930Myb domain
SuperFamilySSF466894.12E-288105IPR009057Homeodomain-like
SMARTSM007176.7E-11959IPR001005SANT/Myb domain
PfamPF002497.7E-121055IPR001005SANT/Myb domain
CDDcd001673.19E-111257No hitNo description
Gene3DG3DSA:1.10.10.603.6E-1859111IPR009057Homeodomain-like
PROSITE profilePS5129418.09662113IPR017930Myb domain
SMARTSM007175.2E-1263111IPR001005SANT/Myb domain
CDDcd001673.71E-1066105No hitNo description
PfamPF002497.6E-1266105IPR001005SANT/Myb domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0048235Biological Processpollen sperm cell differentiation
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 266 aa     Download sequence    Send to blast
MEGKREEIRK GPWKAEEDEV LINHVNKYGP RDWSSIRSKG LLQRTGKSCR LRWVNKLRPN  60
LKNGCKFSAE EERVVIDLQA QFGNKWARIA TYLPGRTDND VKNFWSSRQK RLARILHNST  120
PSSSTSKSLK IKREIPTFRE PISMVTLPDL VNPNPNLDDA AALHLIDHHP TETNLHIPTP  180
TFSQENQRLL NRLDEDPYFF DVVLGPLDST EISLGQPFFE PARSCRHIMR DDENANSVTP  240
DSFFDDFPAD MFDQMESLPS PSHTS*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1h8a_C1e-28711124126MYB TRANSFORMING PROTEIN
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that acts as a positive regulator of male germline development by promoting both gametic cell specification and cell cycle progression (PubMed:15694308, PubMed:15618418, PubMed:19300502, PubMed:21285328). Binds to canonical MYB sites 5'-AACCGTC-3', 5'-AAACCGC-3' and 5'-AACCGT-3' in promoters to trigger the expression of male germline-specific or enriched genes (e.g. MGH3, GEX2 and GCS1), including those required for fertilization (PubMed:21285328, PubMed:19300502). Required for sperm cell specification leading to pollen maturation by activating a germline-specific regulon (PubMed:21285328, PubMed:15694308, PubMed:15618418, PubMed:19300502). Involved in pollen mitosis entry at G2-M transition via the regulation of CYCB1-1, DAZ1 and DAZ2 expression (PubMed:15618418, PubMed:19300502, PubMed:24876252). {ECO:0000269|PubMed:15618418, ECO:0000269|PubMed:15694308, ECO:0000269|PubMed:19300502, ECO:0000269|PubMed:21285328, ECO:0000269|PubMed:24876252}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapevm.model.supercontig_37.96
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Repressed by the microRNA 159 (miR159); the production of miR159 is stimulated by the anaphase promoting complex/cyclosome (APC/C) (PubMed:21441434). Activated by ARID1 in male germline cells via specific histone acetylation regulation (e.g. H3K9Ac) (PubMed:25057814). {ECO:0000269|PubMed:21441434, ECO:0000269|PubMed:25057814}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_021900525.10.0transcription factor DUO1
SwissprotA0A178VEK75e-98DUO1_ARATH; Transcription factor DUO1
TrEMBLA0A061DVG41e-108A0A061DVG4_THECC; Myb-like HTH transcriptional regulator family protein, putative
STRINGevm.model.supercontig_37.960.0(Carica papaya)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM65512842
Representative plantOGRP5171784
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G60460.13e-78MYB family protein
Publications ? help Back to Top
  1. Zheng B,He H,Zheng Y,Wu W,McCormick S
    An ARID domain-containing protein within nuclear bodies is required for sperm cell formation in Arabidopsis thaliana.
    PLoS Genet., 2014. 10(7): p. e1004421
    [PMID:25057814]
  2. Peters B, et al.
    A Conserved cis-Regulatory Module Determines Germline Fate through Activation of the Transcription Factor DUO1 Promoter.
    Plant Physiol., 2017. 173(1): p. 280-293
    [PMID:27624837]
  3. Zheng Z, et al.
    Target RNA Secondary Structure Is a Major Determinant of miR159 Efficacy.
    Plant Physiol., 2017. 174(3): p. 1764-1778
    [PMID:28515145]