PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MELO3C026161P1
Organism
Cucumis melo
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis
Family ARF
Protein Properties Length: 841aa    MW: 93176.9 Da    PI: 6.5435
Description ARF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MELO3C026161P1genomeMELONOMICSView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B374.99.5e-24147248199
                     EEEE-..-HHHHTT-EE--HHH.HTT......---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHHHHHHT--TT-EEEEEE-SSSE CS
              B3   1 ffkvltpsdvlksgrlvlpkkfaeeh......ggkkeesktltledesgrsWevkliyrkksgryvltkGWkeFvkangLkegDfvvFkldgrse 89 
                     f+k+lt sd++++g +++ +++a+e+      + + + +++l+ +d++g++W++++i+r++++r++l++GW+ Fv++++L +gD ++F   + ++
  MELO3C026161P1 147 FCKTLTASDTSTHGGFSVLRRHADEClppldmSRQ-PPTQELVAKDLHGNEWRFRHIFRGQPRRHLLQSGWSVFVSSKRLVAGDAFIFL--RGEN 238
                     99*****************************7333.34459************************************************..4499 PP

                     E..EEEEE-S CS
              B3  90 felvvkvfrk 99 
                     +el+v+v+r+
  MELO3C026161P1 239 GELRVGVRRA 248
                     99*****996 PP
2Auxin_resp120.51.3e-39273355183
      Auxin_resp   1 aahaastksvFevvYnPrastseFvvkvekvekalkvkvsvGmRfkmafetedsserrlsGtvvgvsdldpvrWpnSkWrsLk 83 
                     a+ha+st+++F+v+Y+Pr+s+seF+v+++++++++k+++++GmRfkm+fe+e+++e+r++Gt++g +d+dp rW++SkWr+Lk
  MELO3C026161P1 273 AWHAISTGTMFTVYYKPRTSPSEFIVPYDQYMESIKKSYTIGMRFKMRFEGEEAPEQRFTGTIIGCEDADPKRWKDSKWRCLK 355
                     89*******************************************************************************96 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:2.40.330.106.1E-41144262IPR015300DNA-binding pseudobarrel domain
SuperFamilySSF1019362.75E-40144276IPR015300DNA-binding pseudobarrel domain
CDDcd100178.08E-22145247No hitNo description
PfamPF023621.1E-21147248IPR003340B3 DNA binding domain
SMARTSM010192.0E-23147249IPR003340B3 DNA binding domain
PROSITE profilePS5086312.012147249IPR003340B3 DNA binding domain
PfamPF065077.2E-37273355IPR010525Auxin response factor
PfamPF023094.1E-11704800IPR033389AUX/IAA domain
SuperFamilySSF542772.21E-11714792No hitNo description
PROSITE profilePS5174525.528715799IPR000270PB1 domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0008285Biological Processnegative regulation of cell proliferation
GO:0009737Biological Processresponse to abscisic acid
GO:0009911Biological Processpositive regulation of flower development
GO:0010047Biological Processfruit dehiscence
GO:0010150Biological Processleaf senescence
GO:0010227Biological Processfloral organ abscission
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0048481Biological Processplant ovule development
GO:0005634Cellular Componentnucleus
GO:0005515Molecular Functionprotein binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 841 aa     Download sequence    Send to blast
MASSEVSINP NSASFNDHAD STKDTSDPPN ALSPRDADIA LYTELWNACA GPLVSVPREN  60
ERVFYFPQGH IEQVEASTSQ VADQQMPVYN LPSKILCRVI NVHLKAEPET DEVFAQITLL  120
PEANQDEHAV DKEPPPPPPR RFHVHSFCKT LTASDTSTHG GFSVLRRHAD ECLPPLDMSR  180
QPPTQELVAK DLHGNEWRFR HIFRGQPRRH LLQSGWSVFV SSKRLVAGDA FIFLRGENGE  240
LRVGVRRAMR QHGNVPSSVI SSHSMHLGVL ATAWHAISTG TMFTVYYKPR TSPSEFIVPY  300
DQYMESIKKS YTIGMRFKMR FEGEEAPEQR FTGTIIGCED ADPKRWKDSK WRCLKVRWDE  360
TSTISRPEKV SPWKIEPALA PPALNPLPMT RPKRPRSNMV STSPDSSVLT REGSSRVTVD  420
PSPASVFTRV LQGQEFSTLR GNFIDGSDPD VAEKSVMWPP SLDDEKVDVV STSKKHGADS  480
WIPPGRSEPT YADLLSGFGA DMDSSLGVRA AMGDSAVVTA NSIRKHAMEQ DGKFSFLGGS  540
SWSVLPSGLS LNLVDSSQKG HIRAGDLSYQ VRGNATFNGF GDHSISHCPR TEQPHGNWLM  600
PPPSSHFDYP IHSSELMSKP MLFQNQDILK PKDGNCKLFG ISLVKNPAIP DPVGLNRNMM  660
NEADVMHSNV HQIHSIESGL KSELPRGSKL ADKSVAISEA DKLQQTCKSQ GTSARSCTKV  720
HKQGIALGRS VDLSRFNNYD ELVAELDQLF EFGGELLAPK KNWLIVYTDD EGDMMLVGDD  780
PWREFCGMVR KIFIYTREEV QKMNPGSLNL KGDENPSVEG EEAKETKSQA VPSMSAPESS  840
*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4ldv_A1e-1774037718354Auxin response factor 1
4ldw_A1e-1774037718354Auxin response factor 1
4ldw_B1e-1774037718354Auxin response factor 1
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtAuxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs) (By similarity). Could act as transcriptional activator or repressor (PubMed:26959229, PubMed:26716451, PubMed:27645097, PubMed:28167023). Involved in the control of fruit ripening process (PubMed:26959229, PubMed:26716451, PubMed:28167023). Regulates expression of a number of ripening regulators, transcription factors, and ethylene biosynthesis and signaling components (PubMed:26959229, PubMed:26716451). May act as a transcriptional repressor of auxin-responsive genes (PubMed:26716451). Regulates vegetative growth, lateral root formation and flower organ senescence, possibly partially by regulating gene expression of auxin and ethylene response factor (ERF) genes (PubMed:28167023). Plays a negative role in axillary shoot meristem formation (PubMed:27645097). {ECO:0000255|RuleBase:RU004561, ECO:0000269|PubMed:26716451, ECO:0000269|PubMed:26959229, ECO:0000269|PubMed:27645097, ECO:0000269|PubMed:28167023}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00574DAPTransfer from AT5G62000Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By tomato fruit ripening. Expression in tomato fruits is up-regulated by exogenous application of ethylene and down-regulated by inhibition of ethylene receptors with 1-methylcyclopropene (1-MCP) (PubMed:26959229, PubMed:26716451). Up-regulated by plant hormone abscisic acid (ABA) in tomato fruits (PubMed:26959229). Expression is not up-regulated by plant hormone auxin in tomato fruits (PubMed:26716451). Up-regulated by auxin and gibberellic acid (GA), and down-regulated by ethylene in seedlings (PubMed:28167023). Down-regulated during decapitation-induced axillary shoot development and by excision of immature leaves. Down-regulation is inhibited by the application of auxin on the cut surface (PubMed:27645097). {ECO:0000269|PubMed:26716451, ECO:0000269|PubMed:26959229, ECO:0000269|PubMed:27645097, ECO:0000269|PubMed:28167023}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankKU3234080.0KU323408.1 UNVERIFIED: Trichosanthes dioica clone TdARF_6 auxin response factor-like mRNA, partial sequence.
GenBankKU3234220.0KU323422.1 UNVERIFIED: Trichosanthes dioica clone TdARF_30 auxin response factor-like mRNA, partial sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_008464365.10.0PREDICTED: auxin response factor 2
RefseqXP_008464366.10.0PREDICTED: auxin response factor 2
SwissprotQ2LAJ30.0ARF2A_SOLLC; Auxin response factor 2A
TrEMBLA0A1S3CLA60.0A0A1S3CLA6_CUCME; Auxin response factor
TrEMBLE5GBL70.0E5GBL7_CUCME; Auxin response factor
STRINGXP_008464365.10.0(Cucumis melo)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF32813366
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G62000.30.0auxin response factor 2
Publications ? help Back to Top
  1. Tomato Genome Consortium
    The tomato genome sequence provides insights into fleshy fruit evolution.
    Nature, 2012. 485(7400): p. 635-41
    [PMID:22660326]
  2. Breitel DA, et al.
    AUXIN RESPONSE FACTOR 2 Intersects Hormonal Signals in the Regulation of Tomato Fruit Ripening.
    PLoS Genet., 2016. 12(3): p. e1005903
    [PMID:26959229]
  3. Xu T, et al.
    SlARF2a plays a negative role in mediating axillary shoot formation.
    Sci Rep, 2016. 6: p. 33728
    [PMID:27645097]
  4. Ren Z,Liu R,Gu W,Dong X
    The Solanum lycopersicum auxin response factor SlARF2 participates in regulating lateral root formation and flower organ senescence.
    Plant Sci., 2017. 256: p. 103-111
    [PMID:28167023]