PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | MELO3C024578P1 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis
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Family | E2F/DP | ||||||||
Protein Properties | Length: 356aa MW: 39872.8 Da PI: 4.6901 | ||||||||
Description | E2F/DP family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | E2F_TDP | 81.7 | 6.4e-26 | 70 | 135 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL+llt+kf++l++++++gi++ln++a++L +v ++RRiYDi+NVLe+++liekk kn i wkg MELO3C024578P1 70 RYDSSLGLLTKKFINLIKQARDGILDLNKAAETL---QV--QKRRIYDITNVLEGIGLIEKKLKNIIYWKG 135 6899******************************...99..****************************98 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Gene3D | G3DSA:1.10.10.10 | 3.5E-28 | 67 | 137 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 3.1E-31 | 70 | 135 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
SuperFamily | SSF46785 | 2.65E-17 | 70 | 133 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
Pfam | PF02319 | 1.7E-23 | 72 | 135 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
SuperFamily | SSF144074 | 1.07E-32 | 149 | 252 | No hit | No description |
Pfam | PF16421 | 9.7E-32 | 151 | 250 | IPR032198 | E2F transcription factor, CC-MB domain |
CDD | cd14660 | 7.87E-45 | 151 | 252 | No hit | No description |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0006355 | Biological Process | regulation of transcription, DNA-templated | ||||
GO:0005667 | Cellular Component | transcription factor complex | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 356 aa Download sequence Send to blast |
MYNNVVKSND YIHDEGSSKD ALSCVQTPVS AKGGRAYNKS KTSRKTTSGP QTPISDTSTY 60 SPLTPAGNCR YDSSLGLLTK KFINLIKQAR DGILDLNKAA ETLQVQKRRI YDITNVLEGI 120 GLIEKKLKNI IYWKGFNQQI PGNVDSDASM LQVDVENLSF EERRLDDKIR AMQERLRNLS 180 EDENIQKWLF VTEDDIKNLP CFQNETLIAI KAPHGTTLEV PDPDEAVDYP QRRYRIVLRS 240 TMGPIDVYLV SQFEEKFEEM NVVQPPSSFL HASSSGSNEH LATEAIIGES SRNEIEPLAH 300 LSQHSSSCDV NGSNEFPGGM MKILPSDIDN DADYWLLSDA EVSITDMWRT DCILI* |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
1cf7_A | 2e-24 | 62 | 135 | 2 | 73 | PROTEIN (TRANSCRIPTION FACTOR E2F-4) |
Search in ModeBase |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}. |
Annotation -- Nucleotide ? help Back to Top | ||||||
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Source | Hit ID | E-value | Description | |||
GenBank | LN681876 | 1e-129 | LN681876.1 Cucumis melo genomic scaffold, anchoredscaffold00068. | |||
GenBank | LN713262 | 1e-129 | LN713262.1 Cucumis melo genomic chromosome, chr_8. |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_016902873.1 | 0.0 | PREDICTED: transcription factor E2FA-like isoform X2 | ||||
Swissprot | Q9FNY0 | 1e-135 | E2FA_ARATH; Transcription factor E2FA | ||||
TrEMBL | A0A1S4E3R8 | 0.0 | A0A1S4E3R8_CUCME; transcription factor E2FA-like isoform X2 | ||||
STRING | XP_008462611.1 | 0.0 | (Cucumis melo) |
Orthologous Group ? help Back to Top | |||
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Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Fabids | OGEF1947 | 34 | 90 |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT2G36010.1 | 1e-139 | E2F transcription factor 3 |
Publications ? help Back to Top | |||
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