PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MELO3C024041P1
Organism
Cucumis melo
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis
Family bHLH
Protein Properties Length: 386aa    MW: 42700.9 Da    PI: 7.6061
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MELO3C024041P1genomeMELONOMICSView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH40.26.1e-13241287455
                     HHHHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHHH CS
             HLH   4 ahnerErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksLq 55 
                     +h e+Er+RR+++N++f  Lr ++P+ +      K++Ka+ L  A+ YI +Lq
  MELO3C024041P1 241 NHVEAERQRREKLNQRFYALRAVVPNiS------KMDKASLLGDAITYITDLQ 287
                     799***********************66......*****************99 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF142151.5E-2016113IPR025610Transcription factor MYC/MYB N-terminal
PROSITE profilePS5088816.831237286IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474596.02E-18240300IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000831.44E-13240291No hitNo description
Gene3DG3DSA:4.10.280.104.5E-18241298IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000102.0E-10241287IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003536.2E-14243292IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 386 aa     Download sequence    Send to blast
MLQSSFGRSD EDGYGARRDE ASDIEMLYLT SKYYKFMCDS GSSLGESYKS GKSIWASDAT  60
SCLRNYQSRG FLAKVAGLQT LVFVPVKLGV VELGSIKSIP EDQAVLELVR AAFGGSNTAQ  120
LKAFPRIFGH ELSLGGTKPR SLSINFSPKL EDDTNYSSEA YELQGLGGNH IFGNSSNGCR  180
GDDNDAKMFP HGNQEVVGGF NAQTRLSTME FPRDESSPQG DDRKPRKRGR KPANGREEPL  240
NHVEAERQRR EKLNQRFYAL RAVVPNISKM DKASLLGDAI TYITDLQMKI KVMETEKQIA  300
SGREKNTEID FHAREEDAVV RVSCPLDSHP VSKVIKTFRE HQIEAQESNV KASTDNDKVI  360
HSFFIRTEGG AAEQLKEKLV AALSK*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5gnj_A7e-29235297264Transcription factor MYC2
5gnj_B7e-29235297264Transcription factor MYC2
5gnj_E7e-29235297264Transcription factor MYC2
5gnj_F7e-29235297264Transcription factor MYC2
5gnj_G7e-29235297264Transcription factor MYC2
5gnj_I7e-29235297264Transcription factor MYC2
5gnj_M7e-29235297264Transcription factor MYC2
5gnj_N7e-29235297264Transcription factor MYC2
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1222230RKPRKRGRK
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that negatively regulates jasmonate (JA) signaling (PubMed:30610166). Negatively regulates JA-dependent response to wounding, JA-induced expression of defense genes, JA-dependent responses against herbivorous insects, and JA-dependent resistance against Botrytis cinerea infection (PubMed:30610166). Plays a positive role in resistance against the bacterial pathogen Pseudomonas syringae pv tomato DC3000 (PubMed:30610166). {ECO:0000269|PubMed:30610166}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00099PBMTransfer from AT4G16430Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by wounding, feeding with herbivorous insects, infection with the fungal pathogen Botrytis cinerea and infection with the bacterial pathogen Pseudomonas syringae pv tomato DC3000. {ECO:0000269|PubMed:30610166}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankLN6818350.0LN681835.1 Cucumis melo genomic scaffold, anchoredscaffold00064.
GenBankLN7132580.0LN713258.1 Cucumis melo genomic chromosome, chr_4.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_008461882.10.0PREDICTED: transcription factor bHLH3
SwissprotA0A3Q7H2161e-144MTB3_SOLLC; Transcription factor MTB3
TrEMBLA0A1S3CG810.0A0A1S3CG81_CUCME; transcription factor bHLH3
STRINGXP_008461882.10.0(Cucumis melo)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G16430.11e-130bHLH family protein
Publications ? help Back to Top
  1. Tomato Genome Consortium
    The tomato genome sequence provides insights into fleshy fruit evolution.
    Nature, 2012. 485(7400): p. 635-41
    [PMID:22660326]
  2. Sun H,Fan HJ,Ling HQ
    Genome-wide identification and characterization of the bHLH gene family in tomato.
    BMC Genomics, 2015. 16: p. 9
    [PMID:25612924]
  3. Liu Y, et al.
    MYC2 Regulates the Termination of Jasmonate Signaling via an Autoregulatory Negative Feedback Loop.
    Plant Cell, 2019. 31(1): p. 106-127
    [PMID:30610166]