PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MELO3C019736P1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis
Family bHLH
Protein Properties Length: 254aa    MW: 27914.2 Da    PI: 10.5435
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MELO3C019736P1genomeMELONOMICSView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH23.31.2e-072751730
                    HHHHHHHHHHHHHHHHHHCTSCC.C CS
             HLH  7 erErrRRdriNsafeeLrellPk.a 30
                      Er+RR+++N++++ Lr+++P+ +
  MELO3C019736P1 27 LSERNRRRKLNERLFALRSVVPNiS 51
                    57********************955 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
CDDcd000831.39E-51856No hitNo description
PROSITE profilePS5088810.0362098IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474596.02E-82056IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.102.1E-62656IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000103.4E-52751IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF1012784.05E-3249190IPR013992Adenylate cyclase-associated CAP, N-terminal
PfamPF012134.5E-3451224IPR013992Adenylate cyclase-associated CAP, N-terminal
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0007010Biological Processcytoskeleton organization
GO:0003779Molecular Functionactin binding
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 254 aa     Download sequence    Send to blast
KLGIRRPLPS YYDSSLLDGS TTSKNILSER NRRRKLNERL FALRSVVPNI SKKPDLAGLA  60
EFFKPLNEVT MKANALTGGR RSDFFNHLKA TADSLSTLAW FAFIGKDCGM SMPIAHVQES  120
WQMAKFYNNK VLVEYRNKDP NHVEWAKVIK ELYLTVWSVT GKTTTSAAPK ASPPPKTSAP  180
GAPAPPPPPP ASLFSSEPSQ ASSSKPKEGM ATVFQEINYG KPVTLAIVVS NFRNIHCSLV  240
FPKLSPSLLF VHL*
Functional Description ? help Back to Top
Source Description
UniProtActin monomer binding protein that accelerates the exchange of ADP for ATP. Regulates the pool of unpolymerized ATP-actin. Key intermediate between actin-depolymerizing factor (ADF)-mediated disassembly and the profilin-based nucleation and elongation machinery. {ECO:0000269|PubMed:11826305, ECO:0000269|PubMed:17538023, ECO:0000269|PubMed:17635992}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankLN6819211e-165LN681921.1 Cucumis melo genomic scaffold, anchoredscaffold00039.
GenBankLN7132651e-165LN713265.1 Cucumis melo genomic chromosome, chr_11.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_008457926.11e-79PREDICTED: cyclase-associated protein 1-like
SwissprotO659026e-59ACAP1_ARATH; Cyclase-associated protein 1
TrEMBLA0A1S3C7X52e-78A0A1S3C7X5_CUCME; Adenylyl cyclase-associated protein
STRINGXP_008450201.11e-105(Cucumis melo)
Publications ? help Back to Top
  1. Barrero RA,Umeda M,Yamamura S,Uchimiya H
    Arabidopsis CAP regulates the actin cytoskeleton necessary for plant cell elongation and division.
    Plant Cell, 2002. 14(1): p. 149-63
    [PMID:11826305]
  2. Ndimba BK,Chivasa S,Simon WJ,Slabas AR
    Identification of Arabidopsis salt and osmotic stress responsive proteins using two-dimensional difference gel electrophoresis and mass spectrometry.
    Proteomics, 2005. 5(16): p. 4185-96
    [PMID:16254930]
  3. Chaudhry F,Guérin C,von Witsch M,Blanchoin L,Staiger CJ
    Identification of Arabidopsis cyclase-associated protein 1 as the first nucleotide exchange factor for plant actin.
    Mol. Biol. Cell, 2007. 18(8): p. 3002-14
    [PMID:17538023]
  4. Deeks MJ, et al.
    Arabidopsis CAP1 - a key regulator of actin organisation and development.
    J. Cell. Sci., 2007. 120(Pt 15): p. 2609-18
    [PMID:17635992]
  5. Bai L,Zhou Y,Ma X,Gao L,Song CP
    Arabidopsis CAP1-mediated ammonium sensing required reactive oxygen species in plant cell growth.
    Plant Signal Behav, 2014. 9(8): p. e29582
    [PMID:25763633]