PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

MELO3C017257P1

Organism

Cucumis melo

Taxonomic ID

3656

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis

Family

bHLH

Protein Properties

Length: 531aa MW: 57979.4 Da PI: 8.2333

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
MELO3C017257P1	genome	MELONOMICS	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	53.7	3.7e-17	259	308	2	55
HHHHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS HLH 2 rrahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 r +h++ E+rRR++iN++f+ Lr l+P++ ++K +Ka+ L ++veYI+ Lq MELO3C017257P1 259 RSKHSATEQRRRSKINDRFQMLRGLIPHS----DQKRDKASFLLEVVEYIQFLQ 308 889***********************9....9*****************9 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:4.10.280.10	2.4E-25	254	329	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	4.06E-19	256	328	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profile	PS50888	16.437	257	307	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	3.88E-15	259	312	No hit	No description
Pfam	PF00010	1.2E-14	259	308	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	3.2E-13	263	313	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006351	Biological Process	transcription, DNA-templated
GO:0009742	Biological Process	brassinosteroid mediated signaling pathway
GO:1902448	Biological Process	positive regulation of shade avoidance
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 531 aa Download sequence Send to blast
MELPQPRPFG AEGSKSTHDF LSLYTHSSPQ LDPRSTAQGS YLKTHDFLQP QERIRKASTK 60 EEADVERPPP PAPPPSVEHL LPGGIGTYSI SHVSYFDQRV VLPKPEGSVF TGVRSSSSAE 120 RNDENSNGSS FAAAGSGFTL WEECSVKKGK TGKENNVGDR PHEPRASTSQ WTASMERPSQ 180 SSSNNHHNTF SCLSSSQPTG TKNPTFMEML KSAQSTSQDE ELDDDGDFVI KKETSTANKG 240 GLRIKVDGNS SDQKANTPRS KHSATEQRRR SKINDRFQML RGLIPHSDQK RDKASFLLEV 300 VEYIQFLQEK VQKYEGSYQE WNQEMAKLVP LRNNQRSADV YNDQPRGISS GSVPALVLAA 360 KFIEKNSPLS PIVPGSSHNA VDSDTSSAST LKAVDHHSGR TSNALPFPMS MPPKLSACTR 420 DGNLVPQPPK QLSSGTDHSS LRPEIRSCEA RCYNSDVAVA SEMQKEQDLT IEGGTINISS 480 IYSQGLLNTL THALQSSGVD LSQARISVQI ELGKRATRRA ISPASIVKVF *

Sequence ? help Back to Top

Protein Sequence Length: 531 aa Download sequence Send to blast

MELPQPRPFG AEGSKSTHDF LSLYTHSSPQ LDPRSTAQGS YLKTHDFLQP QERIRKASTK  60
EEADVERPPP PAPPPSVEHL LPGGIGTYSI SHVSYFDQRV VLPKPEGSVF TGVRSSSSAE  120
RNDENSNGSS FAAAGSGFTL WEECSVKKGK TGKENNVGDR PHEPRASTSQ WTASMERPSQ  180
SSSNNHHNTF SCLSSSQPTG TKNPTFMEML KSAQSTSQDE ELDDDGDFVI KKETSTANKG  240
GLRIKVDGNS SDQKANTPRS KHSATEQRRR SKINDRFQML RGLIPHSDQK RDKASFLLEV  300
VEYIQFLQEK VQKYEGSYQE WNQEMAKLVP LRNNQRSADV YNDQPRGISS GSVPALVLAA  360
KFIEKNSPLS PIVPGSSHNA VDSDTSSAST LKAVDHHSGR TSNALPFPMS MPPKLSACTR  420
DGNLVPQPPK QLSSGTDHSS LRPEIRSCEA RCYNSDVAVA SEMQKEQDLT IEGGTINISS  480
IYSQGLLNTL THALQSSGVD LSQARISVQI ELGKRATRRA ISPASIVKVF *

Functional Description ? help Back to Top
Source	Description
UniProt	Positive brassinosteroid-signaling protein. Transcription factor that bind specifically to the DNA sequence 5'-CANNTG-3'(E box). Can bind individually to the promoter as a homodimer or synergistically as a heterodimer with BZR2/BES1. Does not itself activate transcription but enhances BZR2/BES1-mediated target gene activation. {ECO:0000269\|PubMed:15680330}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00498	DAP	Transfer from AT5G08130	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Repressed by cold treatment. {ECO:0000269\|PubMed:12679534}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	LN681813	0.0	LN681813.1 Cucumis melo genomic scaffold, anchoredscaffold00030.
GenBank	LN713256	0.0	LN713256.1 Cucumis melo genomic chromosome, chr_2.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_008453321.1	0.0	PREDICTED: transcription factor BIM1
Swissprot	Q9LEZ3	1e-110	BIM1_ARATH; Transcription factor BIM1
TrEMBL	A0A1S3BX43	0.0	A0A1S3BX43_CUCME; transcription factor BIM1
STRING	XP_008453321.1	0.0	(Cucumis melo)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF7252	31	45

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G08130.4	1e-103	bHLH family protein

Publications ? help Back to Top
Liang T, et al. UVR8 Interacts with BES1 and BIM1 to Regulate Transcription and Photomorphogenesis in Arabidopsis. Dev. Cell, 2018. 44(4): p. 512-523.e5 [PMID:29398622]