PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MELO3C011979P1
Organism
Cucumis melo
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis
Family TALE
Protein Properties Length: 326aa    MW: 36950.6 Da    PI: 4.7896
Description TALE family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MELO3C011979P1genomeMELONOMICSView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox28.92e-092663002155
                     HSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHH CS
        Homeobox  21 knrypsaeereeLAkklgLterqVkvWFqNrRake 55 
                     k +yp+++++  LA+++gL+++q+ +WF N+R ++
  MELO3C011979P1 266 KWPYPTEADKVALAERTGLDQKQINNWFINQRKRH 300
                     679*****************************885 PP
2ELK25.62.7e-09220241122
             ELK   1 ELKhqLlrKYsgyLgsLkqEFs 22 
                     +LK+ Llr +++++++Lk EFs
  MELO3C011979P1 220 DLKDKLLRRFGSHISTLKLEFS 241
                     69*******************8 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM012551.0E-1980124IPR005540KNOX1
PfamPF037901.2E-2082123IPR005540KNOX1
SMARTSM012568.9E-27130181IPR005541KNOX2
PfamPF037912.0E-24134180IPR005541KNOX2
PfamPF037892.2E-7220241IPR005539ELK domain
PROSITE profilePS512139.341220240IPR005539ELK domain
SMARTSM011888.3E-5220241IPR005539ELK domain
PROSITE profilePS5007112.746240303IPR001356Homeobox domain
SuperFamilySSF466891.03E-19241315IPR009057Homeodomain-like
SMARTSM003891.2E-12242307IPR001356Homeobox domain
Gene3DG3DSA:1.10.10.602.6E-27245304IPR009057Homeodomain-like
CDDcd000863.09E-12252304No hitNo description
PfamPF059201.7E-17260299IPR008422Homeobox KN domain
PROSITE patternPS000270278301IPR017970Homeobox, conserved site
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0010073Biological Processmeristem maintenance
GO:0005634Cellular Componentnucleus
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 326 aa     Download sequence    Send to blast
MDEMYGLQST AEYSDKALMS PENLIIPPDY QSLLVSSGEF RDRIPVFGSN ELLSAAASAI  60
SEAEAASITP DIQREEDMVN VIKAKISSHP TYPRLLDAYI DCQKVGAPPE IAHLLEGIRQ  120
ESDFCNRHAV TTCLGVDPEL DEFMETYCDM LVKYKSDLKR PFDEATTFLN KIELQLSNLC  180
NGAFSRSLSD DGAVSSDEEL SGGEMEVVEA EAQTKGENRD LKDKLLRRFG SHISTLKLEF  240
SKKKKKGKLP KEARQTLFEW WNVHYKWPYP TEADKVALAE RTGLDQKQIN NWFINQRKRH  300
WKPSENMQFE GMDNGLSSGR FFRED*
Functional Description ? help Back to Top
Source Description
UniProtPlays a role in meristem function. Contributes to the shoot apical meristem (SAM) maintenance and organ separation by controlling boundary establishment in embryo in a CUC1, CUC2 and STM-dependent manner. Involved in maintaining cells in an undifferentiated, meristematic state. Probably binds to the DNA sequence 5'-TGAC-3'. {ECO:0000269|PubMed:16798887}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Seems to be repressed by AS2 and AS1 but induced by STM, CUC1 and CUC2. {ECO:0000269|PubMed:11311158, ECO:0000269|PubMed:16798887}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankLN6818961e-175LN681896.1 Cucumis melo genomic scaffold, anchoredscaffold00016.
GenBankLN7132641e-175LN713264.1 Cucumis melo genomic chromosome, chr_10.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_008446187.10.0PREDICTED: homeobox protein knotted-1-like 6
SwissprotQ84JS61e-151KNAT6_ARATH; Homeobox protein knotted-1-like 6
TrEMBLA0A1S3BFA40.0A0A1S3BFA4_CUCME; homeobox protein knotted-1-like 6
STRINGXP_008446187.10.0(Cucumis melo)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF62034125
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G23380.11e-136KNOTTED1-like homeobox gene 6
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Khan M, et al.
    Repression of Lateral Organ Boundary Genes by PENNYWISE and POUND-FOOLISH Is Essential for Meristem Maintenance and Flowering in Arabidopsis.
    Plant Physiol., 2015. 169(3): p. 2166-86
    [PMID:26417006]