PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | MELO3C007572P2 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis
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Family | AP2 | ||||||||
Protein Properties | Length: 506aa MW: 55746.1 Da PI: 6.5469 | ||||||||
Description | AP2 family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | AP2 | 53.4 | 6.4e-17 | 145 | 194 | 1 | 55 |
AP2 1 sgykGVrwdkkrgrWvAeIrdpsengkr.krfslgkfgtaeeAakaaiaarkkleg 55 s+y+GV++++++grW+++I+d + k+++lg f+ta Aa+a+++a+ k++g MELO3C007572P2 145 SQYRGVTFYRRTGRWESHIWD------CgKQVYLGGFDTAHAAARAYDRAAIKFRG 194 78*******************......55************************997 PP | |||||||
2 | AP2 | 43.8 | 6.4e-14 | 237 | 287 | 1 | 55 |
AP2 1 sgykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 s+y+GV+ +k grW+A+ + +k+++lg f+t+ eAa+a+++a+ k +g MELO3C007572P2 237 SKYRGVTLHK-CGRWEARMGQF--L-GKKYVYLGLFDTEIEAARAYDKAAIKCNG 287 89********.7******5553..2.26**********99**********99776 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
SuperFamily | SSF54171 | 1.05E-15 | 145 | 203 | IPR016177 | DNA-binding domain |
Pfam | PF00847 | 5.9E-9 | 145 | 194 | IPR001471 | AP2/ERF domain |
SMART | SM00380 | 1.9E-31 | 146 | 208 | IPR001471 | AP2/ERF domain |
Gene3D | G3DSA:3.30.730.10 | 5.7E-17 | 146 | 202 | IPR001471 | AP2/ERF domain |
CDD | cd00018 | 3.15E-11 | 146 | 201 | No hit | No description |
PROSITE profile | PS51032 | 17.701 | 146 | 202 | IPR001471 | AP2/ERF domain |
CDD | cd00018 | 2.04E-25 | 237 | 297 | No hit | No description |
SuperFamily | SSF54171 | 5.89E-17 | 237 | 297 | IPR016177 | DNA-binding domain |
Pfam | PF00847 | 1.4E-9 | 237 | 287 | IPR001471 | AP2/ERF domain |
PROSITE profile | PS51032 | 15.461 | 238 | 295 | IPR001471 | AP2/ERF domain |
SMART | SM00380 | 4.2E-31 | 238 | 301 | IPR001471 | AP2/ERF domain |
Gene3D | G3DSA:3.30.730.10 | 2.3E-16 | 238 | 295 | IPR001471 | AP2/ERF domain |
PRINTS | PR00367 | 4.8E-6 | 239 | 250 | IPR001471 | AP2/ERF domain |
PRINTS | PR00367 | 4.8E-6 | 277 | 297 | IPR001471 | AP2/ERF domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0006355 | Biological Process | regulation of transcription, DNA-templated | ||||
GO:0003677 | Molecular Function | DNA binding | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 506 aa Download sequence Send to blast |
MWDLNDWPDV REEDECSSAK TSIEGEGDEE KGKRVGSLSN SSSSAVVMEE EEVEVEGGSD 60 EEEPTPMVTR QFFPLEETEI PTPLPHASTT SAPPAAAAAF PRAHWVGVKF AHPDPLAALP 120 NNSLTPTDLS HPIKKSRRGP RSRSSQYRGV TFYRRTGRWE SHIWDCGKQV YLGGFDTAHA 180 AARAYDRAAI KFRGVEADIN FSIEDYEDDL KQMGNLTKEE FVHVLRRQST GFPRGSSKYR 240 GVTLHKCGRW EARMGQFLGK KYVYLGLFDT EIEAARAYDK AAIKCNGKEA VTNFDPSIYE 300 NELNPTTESS SNLGDHSLDL SLGNSSSKQN DSSNNGSIGP QHHSSSSSSA DWQRNHGFRP 360 LQLNLENGGG GGGNKNYNNN VERRNRYLES ETMQLLSQTH IQSPSQFSRP HTVGGAPDHH 420 PHSQILLHNH NNQTFNYQIE FSGSSNGHGG RIVGSDLTLS LNDHLQSGPS QVLASAAASS 480 GFAPQIRPSK NWLHNNGFHC LMRPS* |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Probable transcriptional activator that promotes early floral meristem identity (PubMed:7919989). Is required subsequently for the transition of an inflorescence meristem into a floral meristem (PubMed:1675158). Plays a central role in the specification of floral identity, particularly for the normal development of sepals and petals in the wild-type flower, by spatially controlling the expression domains of multiple floral organ identity genes (PubMed:1675158, PubMed:23034631). Acts as A class cadastral protein by repressing the C class floral homeotic gene AGAMOUS in association with other repressors like LEUNIG and SEUSS (PubMed:1675158). Directly represses AGAMOUS by recruiting the transcriptional corepressor TOPLESS and the histone deacetylase HDA19 (PubMed:23034631). It is also required during seed development (PubMed:1675158). {ECO:0000269|PubMed:1675158, ECO:0000269|PubMed:23034631, ECO:0000269|PubMed:7919989}. |
Regulation -- Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | INDUCTION: Negatively regulated by the C class floral homeotic protein AGAMOUS in stamens and carpels. MicroRNA 172 (miRNA172) negatively regulates APETALA2 at the translational level and may modulate its expression pattern. Seems not to be influenced by jasmonate and Alternaria brassicicola. {ECO:0000269|PubMed:12805630, ECO:0000269|PubMed:12893888, ECO:0000269|PubMed:14555699}. |
Regulation -- PlantRegMap ? help Back to Top | ||||||
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Source | Upstream Regulator | Target Gene | ||||
PlantRegMap | Retrieve | - |
Annotation -- Nucleotide ? help Back to Top | ||||||
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Source | Hit ID | E-value | Description | |||
GenBank | LN681875 | 0.0 | LN681875.1 Cucumis melo genomic scaffold, anchoredscaffold00007. | |||
GenBank | LN713262 | 0.0 | LN713262.1 Cucumis melo genomic chromosome, chr_8. |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_008440303.1 | 0.0 | PREDICTED: AP2-like ethylene-responsive transcription factor TOE3 | ||||
Swissprot | P47927 | 1e-122 | AP2_ARATH; Floral homeotic protein APETALA 2 | ||||
TrEMBL | A0A1S3B0D3 | 0.0 | A0A1S3B0D3_CUCME; AP2-like ethylene-responsive transcription factor TOE3 | ||||
STRING | XP_008440303.1 | 0.0 | (Cucumis melo) |
Orthologous Group ? help Back to Top | |||
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Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Fabids | OGEF3784 | 34 | 63 |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT4G36920.2 | 1e-105 | AP2 family protein |