PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MELO3C005617P2
Organism
Cucumis melo
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis
Family MIKC_MADS
Protein Properties Length: 224aa    MW: 25963.4 Da    PI: 8.887
Description MIKC_MADS family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MELO3C005617P2genomeMELONOMICSView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1SRF-TF96.41.2e-30959151
                    S---SHHHHHHHHHHHHHHHHHHHHHHHHHHT-EEEEEEE-TTSEEEEEE- CS
          SRF-TF  1 krienksnrqvtfskRrngilKKAeELSvLCdaevaviifsstgklyeyss 51
                    krien + rqvtfskRrng+lKKA+ELSvLCdaeva+iifs++gklye+s+
  MELO3C005617P2  9 KRIENATSRQVTFSKRRNGLLKKAFELSVLCDAEVALIIFSPRGKLYEFSN 59
                    79***********************************************95 PP
2K-box69.61e-23821721098
           K-box  10 eeakaeslqqela..kLkkeienLqreqRhllGedLesLslkeLqqLeqqLekslkkiRskKnellleqieelqkkekelqeenkaLrkkl 98 
                     ++++  +l++e++   + k++e L+  +R+llG++L+ +s+ eLqqLe+qLe+sl+kiRs+K+++l+++i +l++ ek+l een aL+ k+
  MELO3C005617P2  82 TATEDVQLEKEYDsfSMTKKLEHLEVCKRKLLGDGLDLCSIDELQQLERQLERSLSKIRSRKYQMLKDEITKLKEEEKKLLEENAALQIKV 172
                     333344556666622689*********************************************************************9887 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM004321.1E-39160IPR002100Transcription factor, MADS-box
PROSITE profilePS5006631.286161IPR002100Transcription factor, MADS-box
PROSITE patternPS003500357IPR002100Transcription factor, MADS-box
PRINTSPR004047.7E-31323IPR002100Transcription factor, MADS-box
SuperFamilySSF554554.32E-33381IPR002100Transcription factor, MADS-box
CDDcd002657.49E-42378No hitNo description
PfamPF003195.4E-271057IPR002100Transcription factor, MADS-box
PRINTSPR004047.7E-312338IPR002100Transcription factor, MADS-box
PRINTSPR004047.7E-313859IPR002100Transcription factor, MADS-box
PfamPF014862.3E-2288172IPR002487Transcription factor, K-box
PROSITE profilePS5129713.23488178IPR002487Transcription factor, K-box
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0010048Biological Processvernalization response
GO:0048510Biological Processregulation of timing of transition from vegetative to reproductive phase
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 224 aa     Download sequence    Send to blast
MVRGKTQMKR IENATSRQVT FSKRRNGLLK KAFELSVLCD AEVALIIFSP RGKLYEFSNC  60
SMNKTIDRYQ NRTKDLMSSN STATEDVQLE KEYDSFSMTK KLEHLEVCKR KLLGDGLDLC  120
SIDELQQLER QLERSLSKIR SRKYQMLKDE ITKLKEEEKK LLEENAALQI KVRSESSKKQ  180
DSNQRSESSN HEEIMDVETE LFIGPPERRS NNNNTNNNNN PFL*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5f28_A2e-18169169MEF2C
5f28_B2e-18169169MEF2C
5f28_C2e-18169169MEF2C
5f28_D2e-18169169MEF2C
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor that promotes flowering, especially in response to vernalization by short periods of cold, in an FLC-inpedendent manner. {ECO:0000269|PubMed:16778081}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Maintained at very low levels by the polycomb-group (PcG) proteins MSI1, CLF, and EMF2 via histone methylation (H3K27me3). Derepressed upon cold treatment (vernalization). {ECO:0000269|PubMed:16778081}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankLN6818952e-96LN681895.1 Cucumis melo genomic scaffold, anchoredscaffold00005.
GenBankLN7132632e-96LN713263.1 Cucumis melo genomic chromosome, chr_9.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_008437191.11e-162PREDICTED: agamous-like MADS-box protein AGL19
SwissprotO827432e-78AGL19_ARATH; Agamous-like MADS-box protein AGL19
TrEMBLA0A1S3AT261e-160A0A1S3AT26_CUCME; agamous-like MADS-box protein AGL19
STRINGXP_008437190.11e-161(Cucumis melo)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF66630102
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G22950.18e-64AGAMOUS-like 19
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Suter L,Rüegg M,Zemp N,Hennig L,Widmer A
    Gene regulatory variation mediates flowering responses to vernalization along an altitudinal gradient in Arabidopsis.
    Plant Physiol., 2014. 166(4): p. 1928-42
    [PMID:25339407]