PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Cla017291
Organism
Citrullus lanatus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Citrullus
Family MIKC_MADS
Protein Properties Length: 256aa    MW: 28665.3 Da    PI: 6.5158
Description MIKC_MADS family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Cla017291genomeICuGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1SRF-TF88.34e-28959151
               S---SHHHHHHHHHHHHHHHHHHHHHHHHHHT-EEEEEEE-TTSEEEEEE- CS
     SRF-TF  1 krienksnrqvtfskRrngilKKAeELSvLCdaevaviifsstgklyeyss 51
               krien   rqvtfskRr+g+lKKA+EL +LCdaevaviifs+tgkl+e+ss
  Cla017291  9 KRIENANSRQVTFSKRRAGLLKKAQELAILCDAEVAVIIFSNTGKLFEFSS 59
               79***********************************************96 PP
2K-box60.57e-21921641587
      K-box  15 eslqqelakLkkeienLqreqRhllGedLesLslkeLqqLeqqLekslkkiRskKnellleqieelqkkekel 87 
                ++ ++e++ L++ei +Lq +q +llG+dL+ L +keLq+LeqqL+++l  +++kK++ll+eq+e+++ +  el
  Cla017291  92 KQEHEEVDILRDEITTLQMKQLQLLGKDLTGLGFKELQNLEQQLNEGLLLVKEKKEQLLMEQLEQSRVQVSEL 164
                56789************************************************************99877665 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5006632.352161IPR002100Transcription factor, MADS-box
SMARTSM004322.5E-41160IPR002100Transcription factor, MADS-box
CDDcd002652.86E-43277No hitNo description
SuperFamilySSF554555.23E-32280IPR002100Transcription factor, MADS-box
PROSITE patternPS003500357IPR002100Transcription factor, MADS-box
PRINTSPR004043.6E-29323IPR002100Transcription factor, MADS-box
PfamPF003197.1E-261057IPR002100Transcription factor, MADS-box
PRINTSPR004043.6E-292338IPR002100Transcription factor, MADS-box
PRINTSPR004043.6E-293859IPR002100Transcription factor, MADS-box
PROSITE profilePS5129711.73891202IPR002487Transcription factor, K-box
PfamPF014864.3E-1592164IPR002487Transcription factor, K-box
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0010047Biological Processfruit dehiscence
GO:0010262Biological Processsomatic embryogenesis
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0048577Biological Processnegative regulation of short-day photoperiodism, flowering
GO:0060862Biological Processnegative regulation of floral organ abscission
GO:0060867Biological Processfruit abscission
GO:0071365Biological Processcellular response to auxin stimulus
GO:2000692Biological Processnegative regulation of seed maturation
GO:0005634Cellular Componentnucleus
GO:0005737Cellular Componentcytoplasm
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0042803Molecular Functionprotein homodimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 256 aa     Download sequence    Send to blast
MGRGKIEIKR IENANSRQVT FSKRRAGLLK KAQELAILCD AEVAVIIFSN TGKLFEFSSA  60
GMKHTLARYN KCVESSEATV DVHKVEFLPP QKQEHEEVDI LRDEITTLQM KQLQLLGKDL  120
TGLGFKELQN LEQQLNEGLL LVKEKKEQLL MEQLEQSRVQ VSELRCLFPP VDCPLPAYLE  180
YCSLEQKNIG IRSPDMACNS EIERGDSDTT LHLGKRAPTL LLQSSSIVLL VIGYVFKLIL  240
PVGQAAISCL LQEKGG
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5f28_A7e-22194194MEF2C
5f28_B7e-22194194MEF2C
5f28_C7e-22194194MEF2C
5f28_D7e-22194194MEF2C
6byy_A8e-22195193MEF2 CHIMERA
6byy_B8e-22195193MEF2 CHIMERA
6byy_C8e-22195193MEF2 CHIMERA
6byy_D8e-22195193MEF2 CHIMERA
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor involved in the negative regulation of flowering, probably through the photoperiodic pathway. Acts as both an activator and a repressor of transcription. Binds DNA in a sequence-specific manner in large CArG motif 5'-CC (A/T)8 GG-3'. Participates probably in the regulation of programs active during the early stages of embryo development. Prevents premature perianth senescence and abscission, fruits development and seed desiccation. Stimulates the expression of at least DTA4, LEC2, FUS3, ABI3, AT4G38680/CSP2 and GRP2B/CSP4. Can enhance somatic embryo development in vitro. {ECO:0000269|PubMed:10318690, ECO:0000269|PubMed:10662856, ECO:0000269|PubMed:12226488, ECO:0000269|PubMed:12743119, ECO:0000269|PubMed:14615187, ECO:0000269|PubMed:15084721, ECO:0000269|PubMed:15686521, ECO:0000269|PubMed:17521410, ECO:0000269|PubMed:18305206, ECO:0000269|PubMed:19269998, ECO:0000269|PubMed:19767455, ECO:0000269|PubMed:8953767}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00508DAPTransfer from AT5G13790Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By auxin (2,4-D). Feedback loop leading to direct down-regulation by itself. {ECO:0000269|PubMed:15686521}.
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankLN6818353e-89LN681835.1 Cucumis melo genomic scaffold, anchoredscaffold00064.
GenBankLN7132583e-89LN713258.1 Cucumis melo genomic chromosome, chr_4.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_008461826.11e-141PREDICTED: agamous-like MADS-box protein AGL15 isoform X1
SwissprotQ388471e-66AGL15_ARATH; Agamous-like MADS-box protein AGL15
TrEMBLA0A1S3CFG41e-139A0A1S3CFG4_CUCME; agamous-like MADS-box protein AGL15 isoform X1
STRINGXP_008461826.11e-140(Cucumis melo)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF35823260
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G13790.12e-51AGAMOUS-like 15
Publications ? help Back to Top
  1. Zheng Q,Zheng Y,Perry SE
    Decreased GmAGL15 expression and reduced ethylene synthesis may contribute to reduced somatic embryogenesis in a poorly embryogenic cultivar of Glycine max.
    Plant Signal Behav, 2014.
    [PMID:23838957]
  2. Perry SE,Zheng Q,Zheng Y
    Transcriptome analysis indicates that GmAGAMOUS-Like 15 may enhance somatic embryogenesis by promoting a dedifferentiated state.
    Plant Signal Behav, 2016. 11(7): p. e1197463
    [PMID:27302197]
  3. Cosio C, et al.
    The class III peroxidase PRX17 is a direct target of the MADS-box transcription factor AGAMOUS-LIKE15 (AGL15) and participates in lignified tissue formation.
    New Phytol., 2017. 213(1): p. 250-263
    [PMID:27513887]
  4. Zheng Q,Zheng Y,Ji H,Burnie W,Perry SE
    Gene Regulation by the AGL15 Transcription Factor Reveals Hormone Interactions in Somatic Embryogenesis.
    Plant Physiol., 2016. 172(4): p. 2374-2387
    [PMID:27794101]
  5. Chen N,Veerappan V,Abdelmageed H,Kang M,Allen RD
    HSI2/VAL1 Silences AGL15 to Regulate the Developmental Transition from Seed Maturation to Vegetative Growth in Arabidopsis.
    Plant Cell, 2018. 30(3): p. 600-619
    [PMID:29475938]