PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Cla016990

Organism

Citrullus lanatus

Taxonomic ID

3654

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Citrullus

Family

NAC

Protein Properties

Length: 265aa MW: 30344 Da PI: 5.225

Description

NAC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Cla016990	genome	ICuGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NAM	178	2.6e-55	3	128	1	128
NAM 1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLpkkvkaeekewyfFskrdkkyatgkrknratksgyWkatgkdkevlskkgelv 100 lppGfrFhPtdeel+++yL +kv +++++ +i evd++k+ePwdLp k+k +ekewyf++ rd+ky+tg r+nrat++gyWkatgkdke+l+ ++++v Cla016990 3 LPPGFRFHPTDEELITHYLSPKVLSSTFSS-PAIGEVDLNKCEPWDLPGKAKMGEKEWYFYCVRDRKYPTGLRTNRATEAGYWKATGKDKEILK-GTSVV 100 79***********************999.78***********99999************************************9.999 PP NAM 101 glkktLvfykgrapkgektdWvmheyrl 128 g+kktLvfy+grap+g k++Wvmheyrl Cla016990 101 GMKKTLVFYTGRAPRGDKSNWVMHEYRL 128 **************************97 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF101941	9.81E-64	2	157	IPR003441	NAC domain
PROSITE profile	PS51005	59.351	3	157	IPR003441	NAC domain
Pfam	PF02365	1.9E-29	4	128	IPR003441	NAC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 265 aa Download sequence Send to blast
MELPPGFRFH PTDEELITHY LSPKVLSSTF SSPAIGEVDL NKCEPWDLPG KAKMGEKEWY 60 FYCVRDRKYP TGLRTNRATE AGYWKATGKD KEILKGTSVV GMKKTLVFYT GRAPRGDKSN 120 WVMHEYRLYS NSSSLYSQIL PSNSFQKEWV ICRILKKSES SVGKKGNEIM SDMVTTSSPS 180 SSSLLPPLTE SDAWHVTCFS DSMEEDQNDD ALFCLPDFQE EEDKEREFWS LKVDSSTNNK 240 PSYQYQLHPS PPPTSDYALD CLWNY

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1ut4_A	2e-54	1	161	15	169	NO APICAL MERISTEM PROTEIN
1ut4_B	2e-54	1	161	15	169	NO APICAL MERISTEM PROTEIN
1ut7_A	2e-54	1	161	15	169	NO APICAL MERISTEM PROTEIN
1ut7_B	2e-54	1	161	15	169	NO APICAL MERISTEM PROTEIN
3swm_A	2e-54	1	161	18	172	NAC domain-containing protein 19
3swm_B	2e-54	1	161	18	172	NAC domain-containing protein 19
3swm_C	2e-54	1	161	18	172	NAC domain-containing protein 19
3swm_D	2e-54	1	161	18	172	NAC domain-containing protein 19
3swp_A	2e-54	1	161	18	172	NAC domain-containing protein 19
3swp_B	2e-54	1	161	18	172	NAC domain-containing protein 19
3swp_C	2e-54	1	161	18	172	NAC domain-containing protein 19
3swp_D	2e-54	1	161	18	172	NAC domain-containing protein 19
4dul_A	2e-54	1	161	15	169	NAC domain-containing protein 19
4dul_B	2e-54	1	161	15	169	NAC domain-containing protein 19
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds to DNA in promoters of target genes on a specific bipartite motif 5'-[ACG][CA]GT[AG](5-6n)[CT]AC[AG]-3' (PubMed:23340744). Promotes lateral root development (PubMed:16359384). Triggers the expression of senescence-associated genes during age-, salt- and dark-induced senescence through a regulatory network that may involve cross-talk with salt- and H(2)O(2)-dependent signaling pathways (PubMed:9351240, PubMed:15295076, PubMed:20113437, PubMed:21303842). Regulates also genes during seed germination (PubMed:20113437). Regulates positively aging-induced cell death (PubMed:19229035). Involved in age-related resistance (ARR) against Pseudomonas syringae pv. tomato and Hyaloperonospora arabidopsidis (PubMed:19694953). Antagonizes GLK1 and GLK2 transcriptional activity, shifting the balance from chloroplast maintenance towards deterioration during leaf senescence (PubMed:23459204). Promotes the expression of senescence-associated genes, including ENDO1/BFN1, SWEET15/SAG29 and SINA1/At3g13672, during senescence onset (PubMed:23340744). {ECO:0000269\|PubMed:15295076, ECO:0000269\|PubMed:16359384, ECO:0000269\|PubMed:19229035, ECO:0000269\|PubMed:19694953, ECO:0000269\|PubMed:20113437, ECO:0000269\|PubMed:21303842, ECO:0000269\|PubMed:23340744, ECO:0000269\|PubMed:23459204, ECO:0000269\|PubMed:9351240}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: High levels during senescence (e.g. age-, salt- and dark-related) (PubMed:19229035, PubMed:20113437, PubMed:21511905, PubMed:22930749). By salt stress in an ethylene- and auxin-dependent manner (PubMed:16359384, PubMed:19608714, PubMed:20113437, PubMed:20404534). Induced by H(2)O(2) (PubMed:20404534). Accumulates in response to abscisic acid (ABA), ethylene (ACC) and auxin (NAA) (PubMed:16359384, PubMed:19608714). Repressed by high auxin (IAA) levels (PubMed:21511905). Age-related resistance (ARR)-associated accumulation (PubMed:19694953). Repressed by miR164 (PubMed:19229035). {ECO:0000269\|PubMed:16359384, ECO:0000269\|PubMed:19229035, ECO:0000269\|PubMed:19608714, ECO:0000269\|PubMed:19694953, ECO:0000269\|PubMed:20113437, ECO:0000269\|PubMed:20404534, ECO:0000269\|PubMed:21511905, ECO:0000269\|PubMed:22930749}.
UniProt	INDUCTION: Repressed post-transcriptionally by miR164. {ECO:0000269\|PubMed:15294871, ECO:0000269\|PubMed:17098808, ECO:0000269\|PubMed:18305205, ECO:0000305\|PubMed:15723790}.

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	LN681841	4e-51	LN681841.1 Cucumis melo genomic scaffold, anchoredscaffold00011.
GenBank	LN713258	4e-51	LN713258.1 Cucumis melo genomic chromosome, chr_4.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_023528063.1	1e-123	NAC domain-containing protein 100-like
Swissprot	Q9FKA0	3e-86	NAC92_ARATH; NAC domain-containing protein 92
Swissprot	Q9FLR3	3e-86	NAC79_ARATH; NAC domain-containing protein 79
TrEMBL	A0A1S3B7F7	1e-118	A0A1S3B7F7_CUCME; NAC domain-containing protein 100-like
STRING	XP_008443393.1	1e-119	(Cucumis melo)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF409	34	171

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G39610.1	7e-81	NAC domain containing protein 6

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Manacorda CA, et al. Salicylic acid determines differential senescence produced by two Turnip mosaic virus strains involving reactive oxygen species and early transcriptomic changes. Mol. Plant Microbe Interact., 2013. 26(12): p. 1486-98 [PMID:23945002] Khan M,Rozhon W,Poppenberger B The role of hormones in the aging of plants - a mini-review. Gerontology, 2014. 60(1): p. 49-55 [PMID:24135638] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Vidal EA,Álvarez JM,Gutiérrez RA Nitrate regulation of AFB3 and NAC4 gene expression in Arabidopsis roots depends on NRT1.1 nitrate transport function. Plant Signal Behav, 2014. 9(3): p. e28501 [PMID:24642706] Bohner A,Kojima S,Hajirezaei M,Melzer M,von Wirén N Urea retranslocation from senescing Arabidopsis leaves is promoted by DUR3-mediated urea retrieval from leaf apoplast. Plant J., 2015. 81(3): p. 377-87 [PMID:25440717] Lee MH,Jeon HS,Kim HG,Park OK An Arabidopsis NAC transcription factor NAC4 promotes pathogen-induced cell death under negative regulation by microRNA164. New Phytol., 2017. 214(1): p. 343-360 [PMID:28032643] Sakuraba Y,Bülbül S,Piao W,Choi G,Paek NC Arabidopsis EARLY FLOWERING3 increases salt tolerance by suppressing salt stress response pathways. Plant J., 2017. 92(6): p. 1106-1120 [PMID:29032592] Kim H, et al. Circadian control of ORE1 by PRR9 positively regulates leaf senescence in Arabidopsis. Proc. Natl. Acad. Sci. U.S.A., 2018. 115(33): p. 8448-8453 [PMID:30065116]