PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Cla012549

Organism

Citrullus lanatus

Taxonomic ID

3654

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Citrullus

Family

ERF

Protein Properties

Length: 367aa MW: 40769.9 Da PI: 4.8983

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Cla012549	genome	ICuGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	61.6	1.8e-19	116	165	2	55
AP2 2 gykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 +y+G+r+++ +g+W+AeIrdp++ +r++lg+f taeeAa+a++a +++++g Cla012549 116 QYRGIRQRP-WGKWAAEIRDPRK---GARVWLGTFNTAEEAARAYDAEARRIRG 165 69*****.******954...4**********************998 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF54171	2.09E-22	116	174	IPR016177	DNA-binding domain
Gene3D	G3DSA:3.30.730.10	9.7E-33	116	174	IPR001471	AP2/ERF domain
CDD	cd00018	4.47E-33	116	174	No hit	No description
SMART	SM00380	1.9E-37	116	179	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	24.184	116	173	IPR001471	AP2/ERF domain
Pfam	PF00847	3.0E-12	117	165	IPR001471	AP2/ERF domain
PRINTS	PR00367	8.4E-12	117	128	IPR001471	AP2/ERF domain
PRINTS	PR00367	8.4E-12	139	155	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 367 aa Download sequence Send to blast
MCGGAIISDF IPPSRSNRVT ADHLWPNLKK PKSVKHSSPR SLRSRIFDVD DFEADFQDFK 60 DESDVDQDED DFSDIKPFLF SAPNSACSST CGSSATKSAE FNGQAEKSAN TKRKNQYRGI 120 RQRPWGKWAA EIRDPRKGAR VWLGTFNTAE EAARAYDAEA RRIRGKKAKV NFPDEPLPNT 180 QKRKYSEKVK QHIKANANLK ANQHPDQNYY RTTDFLEVKP PTDQLGYMGS FPASMDSASS 240 DDMLLYFNSD EGSNSDFGWG DQGVKTPEIS SVFSATDSQF TEDMHPMKKP KCSSGDAITA 300 EDGGAKTLSE ELSAFESQMK VFQMPYLDGN WDNSMDAFLG GDATQDGGNS LDLWSFDDLP 360 AVVGGVF

Sequence ? help Back to Top

Protein Sequence Length: 367 aa Download sequence Send to blast

MCGGAIISDF IPPSRSNRVT ADHLWPNLKK PKSVKHSSPR SLRSRIFDVD DFEADFQDFK  60
DESDVDQDED DFSDIKPFLF SAPNSACSST CGSSATKSAE FNGQAEKSAN TKRKNQYRGI  120
RQRPWGKWAA EIRDPRKGAR VWLGTFNTAE EAARAYDAEA RRIRGKKAKV NFPDEPLPNT  180
QKRKYSEKVK QHIKANANLK ANQHPDQNYY RTTDFLEVKP PTDQLGYMGS FPASMDSASS  240
DDMLLYFNSD EGSNSDFGWG DQGVKTPEIS SVFSATDSQF TEDMHPMKKP KCSSGDAITA  300
EDGGAKTLSE ELSAFESQMK VFQMPYLDGN WDNSMDAFLG GDATQDGGNS LDLWSFDDLP  360
AVVGGVF

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1gcc_A	1e-21	116	173	2	60	ETHYLENE RESPONSIVE ELEMENT BINDING FACTOR 1
5wx9_A	6e-21	115	175	13	74	Ethylene-responsive transcription factor ERF096
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor involved in the activation of hypoxic gene expression and in ethylene response. Partially redundant with RAP2-2. Acts as a downstream regulator in the ethylene signaling pathway. {ECO:0000269\|PubMed:22020282, ECO:0000269\|PubMed:22530619}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Up-regulated by hypoxia but not by ethylene. {ECO:0000269\|PubMed:22020282}.

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	LN681829	0.0	LN681829.1 Cucumis melo genomic scaffold, anchoredscaffold00054.
GenBank	LN713258	0.0	LN713258.1 Cucumis melo genomic chromosome, chr_4.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_004144443.1	0.0	PREDICTED: ethylene-responsive transcription factor RAP2-12
Refseq	XP_011651721.1	0.0	PREDICTED: ethylene-responsive transcription factor RAP2-12
Swissprot	Q9SSA8	1e-72	RA212_ARATH; Ethylene-responsive transcription factor RAP2-12
TrEMBL	A0A0A0LC05	0.0	A0A0A0LC05_CUCSA; Uncharacterized protein
STRING	XP_004166643.1	0.0	(Cucumis sativus)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF4808	32	52

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G53910.3	3e-67	related to AP2 12

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Kosmacz M, et al. The stability and nuclear localization of the transcription factor RAP2.12 are dynamically regulated by oxygen concentration. Plant Cell Environ., 2015. 38(6): p. 1094-103 [PMID:25438831] Bui LT,Giuntoli B,Kosmacz M,Parlanti S,Licausi F Constitutively expressed ERF-VII transcription factors redundantly activate the core anaerobic response in Arabidopsis thaliana. Plant Sci., 2015. 236: p. 37-43 [PMID:26025519] Gasch P, et al. Redundant ERF-VII Transcription Factors Bind to an Evolutionarily Conserved cis-Motif to Regulate Hypoxia-Responsive Gene Expression in Arabidopsis. Plant Cell, 2016. 28(1): p. 160-80 [PMID:26668304] Gonzali S, et al. Universal stress protein HRU1 mediates ROS homeostasis under anoxia. Nat Plants, 2015. 1: p. 15151 [PMID:27251529] Paul MV, et al. Oxygen Sensing via the Ethylene Response Transcription Factor RAP2.12 Affects Plant Metabolism and Performance under Both Normoxia and Hypoxia. Plant Physiol., 2016. 172(1): p. 141-53 [PMID:27372243] Shahzad Z, et al. A Potassium-Dependent Oxygen Sensing Pathway Regulates Plant Root Hydraulics. Cell, 2016. 167(1): p. 87-98.e14 [PMID:27641502] Yao Y, et al. ETHYLENE RESPONSE FACTOR 74 (ERF74) plays an essential role in controlling a respiratory burst oxidase homolog D (RbohD)-dependent mechanism in response to different stresses in Arabidopsis. New Phytol., 2017. 213(4): p. 1667-1681 [PMID:28164334] Giuntoli B,Licausi F,van Veen H,Perata P Functional Balancing of the Hypoxia Regulators RAP2.12 and HRA1 Takes Place in vivo in Arabidopsis thaliana Plants. Front Plant Sci, 2017. 8: p. 591 [PMID:28487707] Yao Y,Chen X,Wu AM ERF-VII members exhibit synergistic and separate roles in Arabidopsis. Plant Signal Behav, 2017. 12(6): p. e1329073 [PMID:28537474] Eysholdt-Derzsó E,Sauter M Root Bending Is Antagonistically Affected by Hypoxia and ERF-Mediated Transcription via Auxin Signaling. Plant Physiol., 2017. 175(1): p. 412-423 [PMID:28698356] Giuntoli B, et al. Age-dependent regulation of ERF-VII transcription factor activity in Arabidopsis thaliana. Plant Cell Environ., 2017. 40(10): p. 2333-2346 [PMID:28741696]