PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Cla012123
Organism
Citrullus lanatus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Citrullus
Family ERF
Protein Properties Length: 244aa    MW: 26642.9 Da    PI: 5.0254
Description ERF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Cla012123genomeICuGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP258.81.4e-183685255
        AP2  2 gykGVrwdkkrgrWvAeIrd.psengkrkrfslgkfgtaeeAakaaiaarkkleg 55
               ++ GVr+++ +grWvAeI+d      k+ r +lg+f taeeAa+a+++a+  l+g
  Cla012123 36 KFVGVRQRP-SGRWVAEIKDtT----KKIRMWLGTFETAEEAARAYDEAACLLRG 85
               799******.7*********33....36**********************99987 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.730.103.7E-283692IPR001471AP2/ERF domain
SMARTSM003801.3E-353699IPR001471AP2/ERF domain
PROSITE profilePS5103219.7573693IPR001471AP2/ERF domain
PfamPF008472.8E-133685IPR001471AP2/ERF domain
CDDcd000187.43E-323692No hitNo description
SuperFamilySSF541711.9E-193693IPR016177DNA-binding domain
PRINTSPR003677.7E-83748IPR001471AP2/ERF domain
PRINTSPR003677.7E-85975IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0000302Biological Processresponse to reactive oxygen species
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009723Biological Processresponse to ethylene
GO:0035865Biological Processcellular response to potassium ion
GO:0048528Biological Processpost-embryonic root development
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 244 aa     Download sequence    Send to blast
MEIDFQSPET HGGAAASVIK TSKFKGRNRG NNNGNKFVGV RQRPSGRWVA EIKDTTKKIR  60
MWLGTFETAE EAARAYDEAA CLLRGSNTRT NFIPQISTNS PIASRIRTLL NTKKTLNRKP  120
LENPTITTTT SAATAASAVA DPTIQDDGLF DGAYKPDMTN CLEEREISSC ESSCSDSCGL  180
GVSLAENTAA NSEELELCAF ERMKVERQIS ASLYAINGVQ EYMEAVHEAS EAIWDLPPLC  240
SLFC
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5wx9_A7e-1626102581Ethylene-responsive transcription factor ERF096
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor involved in symbiotic nodule signaling in response to rhizobial Nod factors (NFs) (PubMed:17449807, PubMed:17827349). Binds to the GCC-box (NF-responsive box) of ENOD11 promoter. Acts as transcriptional activator of NF-responsive box-containing target gene promoters in root hairs (PubMed:17827349). Functions as a transcriptional regulator required for root infection by symbiotic rhizobia, infection thread (IT) formation and maintenance, and nodule development. Necessary for NF-induced gene expression and spontaneous nodulation activated by CCAMK. Functions downstream of CCAMK to activate nodulation gene expression (PubMed:17449807). Involved in early stages of root nodule development. Functions redundantly with ERN2. Is essential with ERN2 for the initiation of root hair infection, and nodule organogenesis and development. Required for accurate expression of the NF signaling genes ENOD11 and ENOD12 (PubMed:23077241, PubMed:27208242). {ECO:0000269|PubMed:17449807, ECO:0000269|PubMed:17827349, ECO:0000269|PubMed:23077241, ECO:0000269|PubMed:27208242}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00521DAPTransfer from AT5G19790Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced in roots from 1 to 21 day after inoculation with Sinorhizobium meliloti (PubMed:17449807). Induced by Nod factors in root hairs (PubMed:17827349). {ECO:0000269|PubMed:17449807, ECO:0000269|PubMed:17827349}.
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankLN6818820.0LN681882.1 Cucumis melo genomic scaffold, anchoredscaffold00010.
GenBankLN7132620.0LN713262.1 Cucumis melo genomic chromosome, chr_8.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_004149126.11e-140PREDICTED: ethylene-responsive transcription factor RAP2-11-like
SwissprotA2Q5W12e-94ERN1_MEDTR; Ethylene-responsive transcription factor ERN1
TrEMBLA0A1S3B5E81e-137A0A1S3B5E8_CUCME; ethylene-responsive transcription factor RAP2-11-like
STRINGXP_004149126.11e-140(Cucumis sativus)
STRINGXP_004173145.11e-140(Cucumis sativus)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF33413069
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G19790.13e-22related to AP2 11
Publications ? help Back to Top
  1. Cerri MR, et al.
    Medicago truncatula ERN transcription factors: regulatory interplay with NSP1/NSP2 GRAS factors and expression dynamics throughout rhizobial infection.
    Plant Physiol., 2012. 160(4): p. 2155-72
    [PMID:23077241]
  2. Tang H, et al.
    An improved genome release (version Mt4.0) for the model legume Medicago truncatula.
    BMC Genomics, 2014. 15: p. 312
    [PMID:24767513]
  3. Cerri MR, et al.
    The Symbiosis-Related ERN Transcription Factors Act in Concert to Coordinate Rhizobial Host Root Infection.
    Plant Physiol., 2016. 171(2): p. 1037-54
    [PMID:27208242]