PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | Cc06_g20570 | ||||||||
Common Name | GSCOC_T00023000001 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Gentianales; Rubiaceae; Ixoroideae; Coffeeae; Coffea
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Family | E2F/DP | ||||||||
Protein Properties | Length: 403aa MW: 44627.4 Da PI: 8.9181 | ||||||||
Description | E2F/DP family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | E2F_TDP | 72.5 | 4.6e-23 | 35 | 100 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 rk+ksL+ll+++fl+l+ ++ +++ l+++a +L v +rRRiYDi+NVLe+++++++k+kn+++wkg Cc06_g20570 35 RKQKSLGLLCSNFLRLYDREGVETIGLDDAAARL---GV--ERRRIYDIVNVLESVGVLARKAKNRYTWKG 100 79*****************999************...**..****************************98 PP | |||||||
2 | E2F_TDP | 72.6 | 4.3e-23 | 171 | 251 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 rkeksL lltq+f+kl+ + + ++++l+++ak L+++ ++ k+RR+YDi+NVL +++ iek ++k+++rw g Cc06_g20570 171 RKEKSLALLTQNFVKLFLCMDMDMISLDDAAKILLKNgkdpaMTRSKVRRLYDIANVLASMKFIEKthhpeTRKPAFRWLG 251 79*********************************99****98899*********************99999*******87 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Gene3D | G3DSA:1.10.10.10 | 1.2E-25 | 33 | 101 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SuperFamily | SSF46785 | 2.39E-15 | 35 | 98 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 4.3E-27 | 35 | 100 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Pfam | PF02319 | 2.6E-20 | 36 | 100 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Gene3D | G3DSA:1.10.10.10 | 6.6E-23 | 167 | 252 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 3.2E-29 | 171 | 251 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Pfam | PF02319 | 1.7E-17 | 172 | 251 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
SuperFamily | SSF46785 | 1.27E-11 | 173 | 252 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0006355 | Biological Process | regulation of transcription, DNA-templated | ||||
GO:0032876 | Biological Process | negative regulation of DNA endoreduplication | ||||
GO:0005634 | Cellular Component | nucleus | ||||
GO:0005667 | Cellular Component | transcription factor complex | ||||
GO:0003677 | Molecular Function | DNA binding | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 403 aa Download sequence Send to blast |
MGMELLPSTN QASEAAAAAA AAGGSGGGSQ HIYCRKQKSL GLLCSNFLRL YDREGVETIG 60 LDDAAARLGV ERRRIYDIVN VLESVGVLAR KAKNRYTWKG FGAIPSALQL LKEEGMMTNE 120 NANDGTSSVK TSDDEEDDTY SNLSNYSSQN HNFNPISAPK LPQSSKYADN RKEKSLALLT 180 QNFVKLFLCM DMDMISLDDA AKILLKNGKD PAMTRSKVRR LYDIANVLAS MKFIEKTHHP 240 ETRKPAFRWL GMKGISESGA DPSAIDGSKK RAFGMDLTNR TVRRSKVEPV GDGGLQQGMK 300 VQLKAQVKRE ALEDEVLRPN LQIDSRASTK SYRFGPFAPV NAPHVAASEE NKETQSHDWE 360 SLAATYRPQY HNQALRDLFA HYVEAWKSWY TEVAENPIQL IS* |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
4yo2_A | 3e-36 | 35 | 243 | 4 | 228 | Transcription factor E2F8 |
Search in ModeBase |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Inhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}. |
Binding Motif ? help Back to Top | |||
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Motif ID | Method | Source | Motif file |
MP00397 | DAP | Transfer from AT3G48160 | Download |
Regulation -- PlantRegMap ? help Back to Top | ||||||
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Source | Upstream Regulator | Target Gene | ||||
PlantRegMap | Retrieve | Retrieve |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_027066581.1 | 0.0 | E2F transcription factor-like E2FE isoform X1 | ||||
Swissprot | Q8LSZ4 | 1e-112 | E2FE_ARATH; E2F transcription factor-like E2FE | ||||
TrEMBL | A0A068UCS7 | 0.0 | A0A068UCS7_COFCA; Uncharacterized protein | ||||
STRING | XP_009607525.1 | 1e-159 | (Nicotiana tomentosiformis) |
Orthologous Group ? help Back to Top | |||
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Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Asterids | OGEA2522 | 24 | 57 |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT3G48160.2 | 1e-114 | DP-E2F-like 1 |
Publications ? help Back to Top | |||
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