PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | Cc06_g06370 | ||||||||
Common Name | GSCOC_T00031391001 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Gentianales; Rubiaceae; Ixoroideae; Coffeeae; Coffea
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Family | E2F/DP | ||||||||
Protein Properties | Length: 468aa MW: 51285.5 Da PI: 4.7985 | ||||||||
Description | E2F/DP family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | E2F_TDP | 84.9 | 6.4e-27 | 145 | 210 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL+llt+kf++l++++e+gi++ln++a++L +v ++RRiYDi+NVLe+++liekk kn+i+wkg Cc06_g06370 145 RYDSSLGLLTKKFINLIKHAEDGILDLNKAAETL---EV--QKRRIYDITNVLEGIGLIEKKLKNRIHWKG 210 6899******************************...99..****************************98 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Gene3D | G3DSA:1.10.10.10 | 8.5E-29 | 142 | 212 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SuperFamily | SSF46785 | 3.1E-17 | 145 | 208 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 2.4E-34 | 145 | 210 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Pfam | PF02319 | 3.1E-24 | 147 | 210 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
CDD | cd14660 | 3.27E-47 | 221 | 327 | No hit | No description |
SuperFamily | SSF144074 | 3.66E-33 | 224 | 327 | No hit | No description |
Pfam | PF16421 | 4.1E-32 | 226 | 325 | IPR032198 | E2F transcription factor, CC-MB domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0006355 | Biological Process | regulation of transcription, DNA-templated | ||||
GO:0005634 | Cellular Component | nucleus | ||||
GO:0005667 | Cellular Component | transcription factor complex | ||||
GO:0003677 | Molecular Function | DNA binding | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 468 aa Download sequence Send to blast |
MSTPQAPSRG AAAGGRQIPQ PIKRHLPFSS MKPPFVPPED YHRFSTPAGA GTETVRIQDA 60 EAIVVKSPPI KRKSRTDNHE VSSTDWAASP GNTRTVSSPI CTPVSAKGGK AYGRSKVTKG 120 DMSGPSTPLS NAGSPAPLTP AGSCRYDSSL GLLTKKFINL IKHAEDGILD LNKAAETLEV 180 QKRRIYDITN VLEGIGLIEK KLKNRIHWKG LDASRPDEVE NDASILQAEV ENLSMEERRL 240 DDRIREMRER LRDLSEDEIN EKWLFVTEED IKTLPCFQNE TLIAIKAPHG TTLEVPDPDE 300 AVDYPQRRYR IILRSTMGPI DVYLVSQFEE KFEDVNGGEP SMRYALASSS GSNDNPAAET 360 AVYEKTGLVV GELAEQDTRM AADLDASHDY AGGMMKIVPS ENDADYWLLS DAGVSITDMW 420 KSDAGVEWNG VNMLHDEFGM SDISERPQTP PSGVVDMTYP AANATPR* |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
1cf7_A | 3e-24 | 140 | 211 | 2 | 74 | PROTEIN (TRANSCRIPTION FACTOR E2F-4) |
Search in ModeBase |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}. |
Regulation -- PlantRegMap ? help Back to Top | ||||||
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Source | Upstream Regulator | Target Gene | ||||
PlantRegMap | Retrieve | - |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_027069049.1 | 0.0 | transcription factor E2FA isoform X3 | ||||
Refseq | XP_027176340.1 | 0.0 | transcription factor E2FA isoform X3 | ||||
Swissprot | Q9FNY0 | 1e-161 | E2FA_ARATH; Transcription factor E2FA | ||||
TrEMBL | A0A068UQU0 | 0.0 | A0A068UQU0_COFCA; Uncharacterized protein | ||||
STRING | VIT_08s0007g02510.t01 | 0.0 | (Vitis vinifera) |
Orthologous Group ? help Back to Top | |||
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Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Asterids | OGEA1077 | 24 | 84 |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT2G36010.1 | 1e-165 | E2F transcription factor 3 |
Publications ? help Back to Top | |||
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