PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Cc04_g15910
Common NameGSCOC_T00042380001
Organism
Coffea canephora
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Gentianales; Rubiaceae; Ixoroideae; Coffeeae; Coffea
Family E2F/DP
Protein Properties Length: 403aa    MW: 44547.3 Da    PI: 8.9013
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Cc04_g15910genomeCGSCView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP72.54.6e-2335100171
      E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                  rk+ksL+ll+++fl+l+ ++  +++ l+++a +L    v  +rRRiYDi+NVLe+++++++k+kn+++wkg
  Cc04_g15910  35 RKQKSLGLLCSNFLRLYDREGVETIGLDDAAARL---GV--ERRRIYDIVNVLESVGVLARKAKNRYTWKG 100
                  79*****************999************...**..****************************98 PP
2E2F_TDP72.64.3e-23171251171
      E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 
                  rkeksL lltq+f+kl+ + + ++++l+++ak L+++      ++ k+RR+YDi+NVL +++ iek     ++k+++rw g
  Cc04_g15910 171 RKEKSLALLTQNFVKLFLCMDMDMISLDDAAKILLKNgkdpaMTRSKVRRLYDIANVLASMKFIEKthhpeTRKPAFRWLG 251
                  79*********************************99****98899*********************99999*******87 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.101.2E-2533101IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467852.39E-153598IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013724.3E-2735100IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023192.6E-2036100IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene3DG3DSA:1.10.10.106.6E-23167252IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013723.2E-29171251IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023191.7E-17172251IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467851.27E-11173252IPR011991Winged helix-turn-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 403 aa     Download sequence    Send to blast
MELLPSANQA YEAAAAAAAG GSGGGGGGSQ HIYCRKQKSL GLLCSNFLRL YDREGVETIG  60
LDDAAARLGV ERRRIYDIVN VLESVGVLAR KAKNRYTWKG FGAIPSALQL LKEQGMVTNE  120
NANDGTSSVK TSDDEEDDTY SNLSNYSSQN HNFNPISAPK LPQSSKYADN RKEKSLALLT  180
QNFVKLFLCM DMDMISLDDA AKILLKNGKD PAMTRSKVRR LYDIANVLAS MKFIEKTHHP  240
ETRKPAFRWL GMKGISESGA DPSAIDGSKK RAFGMDLTNM TVKRSKVEPV GDGGLQQGMK  300
EQLKAQVKRE ALEDEVLRPK LQIDSRASTR SYRFGPFAPV NAPQVAASED NKETQSHDWE  360
SLAATYRPQY HNQALRDLFA HYVEAWKSWY TEVAEIPIQL IS*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A2e-36352434228Transcription factor E2F8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_027123815.10.0E2F transcription factor-like E2FE isoform X1
SwissprotQ8LSZ41e-111E2FE_ARATH; E2F transcription factor-like E2FE
TrEMBLA0A068V3110.0A0A068V311_COFCA; Uncharacterized protein
STRINGXP_009607525.11e-159(Nicotiana tomentosiformis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA25222457
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G48160.21e-113DP-E2F-like 1
Publications ? help Back to Top
  1. Chandran D, et al.
    Atypical E2F transcriptional repressor DEL1 acts at the intersection of plant growth and immunity by controlling the hormone salicylic acid.
    Cell Host Microbe, 2014. 15(4): p. 506-13
    [PMID:24721578]
  2. Wang Z, et al.
    Del1 Knockout Mice Developed More Severe Osteoarthritis Associated with Increased Susceptibility of Chondrocytes to Apoptosis.
    PLoS ONE, 2016. 11(8): p. e0160684
    [PMID:27505251]
  3. Heyman J,Polyn S,Eekhout T,De Veylder L
    Tissue-Specific Control of the Endocycle by the Anaphase Promoting Complex/Cyclosome Inhibitors UVI4 and DEL1.
    Plant Physiol., 2017. 175(1): p. 303-313
    [PMID:28698355]