PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | Ciclev10020979m | ||||||||
Common Name | CICLE_v10020979mg | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus
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Family | E2F/DP | ||||||||
Protein Properties | Length: 342aa MW: 38330.7 Da PI: 9.625 | ||||||||
Description | E2F/DP family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | E2F_TDP | 79.8 | 2.4e-25 | 113 | 193 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 r+eksL+lltq+f++l+ +s+ g++tl+evak L+ + +++k+RR+YDi+NVL+++nliek ++k+++rw g Ciclev10020979m 113 RREKSLGLLTQNFVRLFVCSNVGMITLDEVAKLLLGDahntsVMRTKVRRLYDIANVLSSMNLIEKthtadTRKPAFRWLG 193 689**************************************999**************************99*******87 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Gene3D | G3DSA:1.10.10.10 | 1.5E-24 | 108 | 195 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 5.1E-32 | 113 | 193 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
SuperFamily | SSF46785 | 5.85E-14 | 115 | 194 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
Pfam | PF02319 | 2.2E-20 | 115 | 193 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0006355 | Biological Process | regulation of transcription, DNA-templated | ||||
GO:0005634 | Cellular Component | nucleus | ||||
GO:0005667 | Cellular Component | transcription factor complex | ||||
GO:0003677 | Molecular Function | DNA binding | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 342 aa Download sequence Send to blast |
MPQSSSSTKV QDPSSRHYAY SRKQKSLGLL CSKRAKNKYT WKGFKAIPGA LQELKEAGLR 60 DAFTTLDGGN SAKGSDDEDD DEDDDSSSNP NPGSQSDSLN PRSAHKSSKN DSRREKSLGL 120 LTQNFVRLFV CSNVGMITLD EVAKLLLGDA HNTSVMRTKV RRLYDIANVL SSMNLIEKTH 180 TADTRKPAFR WLGVNRLEIG LADSLNLDES RKRTFGTDVT NISFKRKRMD TSINGDISQS 240 IKMEKQMKVD DLVRVVDGSN SENYVNQGPR SYQFGPFAPE SVPEVNTSKN NVKGAHDWES 300 LTSKYRPQYH NQALRDLFSH YMEAWQSWYT EVAGKTIRQI S* |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
4yo2_A | 3e-21 | 30 | 185 | 60 | 228 | Transcription factor E2F8 |
Search in ModeBase |
Nucleic Localization Signal ? help Back to Top | |||
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No. | Start | End | Sequence |
1 | 210 | 227 | RKRTFGTDVTNISFKRKR |
Expression -- Description ? help Back to Top | ||||||
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Source | Description | |||||
Uniprot | DEVELOPMENTAL STAGE: Expressed in a cell cycle-dependent manner. Not detected during early S phase. Expressed at both the G1/S and S/G2 transitions, with a peak during G2. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:18787127}. | |||||
Uniprot | TISSUE SPECIFICITY: Expressed exclusively in mitotically dividing cells. Highly expressed in young leaves and mature flowers. Lower expression in young stalk and in young and mature flowers. {ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366}. |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Inhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}. |
Regulation -- PlantRegMap ? help Back to Top | ||||||
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Source | Upstream Regulator | Target Gene | ||||
PlantRegMap | Retrieve | - |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_024044442.1 | 0.0 | E2F transcription factor-like E2FE | ||||
Swissprot | Q8LSZ4 | 3e-94 | E2FE_ARATH; E2F transcription factor-like E2FE | ||||
TrEMBL | V4VJT1 | 0.0 | V4VJT1_9ROSI; Uncharacterized protein | ||||
STRING | XP_006439729.1 | 0.0 | (Citrus clementina) |
Orthologous Group ? help Back to Top | |||
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Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Malvids | OGEM6304 | 27 | 43 |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT3G48160.2 | 3e-91 | DP-E2F-like 1 |
Link Out ? help Back to Top | |
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Phytozome | Ciclev10020979m |
Entrez Gene | 18048695 |
Publications ? help Back to Top | |||
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