PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Ciclev10004999m
Common NameCICLE_v10004989mg
Organism
Citrus clementina
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus
Family ARR-B
Protein Properties Length: 437aa    MW: 48779 Da    PI: 7.42
Description ARR-B family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Ciclev10004999mgenomeICGCView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1G2-like91.95.4e-29198251155
          G2-like   1 kprlrWtpeLHerFveaveqLGGsekAtPktilelmkvkgLtlehvkSHLQkYRl 55 
                      kpr++W+ eLH++Fv+av++L G++kA+Pk+ilelm+v+gLt+e+v+SHLQkYRl
  Ciclev10004999m 198 KPRVVWSVELHQQFVSAVNHL-GIDKAVPKKILELMNVPGLTRENVASHLQKYRL 251
                      79*******************.********************************8 PP
2Response_reg72.61.6e-24201281109
                      EEEESSSHHHHHHHHHHHHHTTCEEEEEESSHHHHHHHHHHHH..ESEEEEESSCTTSEHHHHHHHHHHHTTTSEEEEEESTTTHHHHHHHHHT CS
     Response_reg   1 vlivdDeplvrellrqalekegyeevaeaddgeealellkekd..pDlillDiempgmdGlellkeireeepklpiivvtahgeeedalealka 92 
                      vl+vdD+p+ +++l+++l+   y ev+ +  +e al++l++++  +D+++  + mp+mdG++ll++   e  +lp+i+++a ++++ + + +  
  Ciclev10004999m  20 VLVVDDDPTCLRILEKMLRTCLY-EVTKCNRAEIALDMLRTNKngYDIVISEVHMPDMDGFKLLEQVGLEM-DLPVIMMSADDSKQVVMKGVTH 111
                      89*********************.***************998889**********************6644.8********************* PP

                      TESEEEESS--HHHHHH CS
     Response_reg  93 GakdflsKpfdpeelvk 109
                      Ga d+l Kp+ +e+l +
  Ciclev10004999m 112 GACDYLIKPVRIEALKN 128
                      *************9986 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PIRSFPIRSF0363925.3E-1671410IPR017053Response regulator B-type, plant
SuperFamilySSF521728.4E-3417142IPR011006CheY-like superfamily
Gene3DG3DSA:3.40.50.23001.8E-4117160No hitNo description
SMARTSM004483.2E-2818130IPR001789Signal transduction response regulator, receiver domain
PROSITE profilePS5011041.61919134IPR001789Signal transduction response regulator, receiver domain
PfamPF000724.9E-2220128IPR001789Signal transduction response regulator, receiver domain
CDDcd001563.62E-2621133No hitNo description
SuperFamilySSF466896.63E-20195255IPR009057Homeodomain-like
PROSITE profilePS5129410.813195254IPR017930Myb domain
Gene3DG3DSA:1.10.10.607.8E-30197255IPR009057Homeodomain-like
TIGRFAMsTIGR015572.5E-25198251IPR006447Myb domain, plants
PfamPF002498.0E-8200250IPR001005SANT/Myb domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0000160Biological Processphosphorelay signal transduction system
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0016021Cellular Componentintegral component of membrane
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 437 aa     Download sequence    Send to blast
MSPASSSVAV SDQFPAGLRV LVVDDDPTCL RILEKMLRTC LYEVTKCNRA EIALDMLRTN  60
KNGYDIVISE VHMPDMDGFK LLEQVGLEMD LPVIMMSADD SKQVVMKGVT HGACDYLIKP  120
VRIEALKNIW QHVVRKRKNE WKDLEQSGSV EERDRQPKPS EEADYSSSAN EGNWRTSKRR  180
KDEEEEMEER DDTSTLKKPR VVWSVELHQQ FVSAVNHLGI DKAVPKKILE LMNVPGLTRE  240
NVASHLQKYR LYLTRLSGVS PHQGNSFISS HSQEPPYGSL SSLSGLDFQT LAATGQIPAQ  300
SLATLQAAGL ARSAAKPGLP MPLVDQRNIF SFDNQKLRFG EGQPQHMSSG KQMNLLHGIP  360
TTMDSKQLLN LHHSAQSLRS LSMQASAHGN PSGQSSHLLM QMAQPLFKLL VLCLIISFLC  420
SLYIFFSHPF GVFYCM*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1irz_A7e-22197257464ARR10-B
Search in ModeBase
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Detected in the whole plant. Predominantly expressed in pollen. {ECO:0000269|PubMed:11370868, ECO:0000269|PubMed:15173562, ECO:0000269|PubMed:9891419}.
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional activator that binds specifically to the DNA sequence 5'-[AG]GATT-3'. Functions as a response regulator involved in His-to-Asp phosphorelay signal transduction system. Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes. Could directly activate some type-A response regulators in response to cytokinins. Involved in the expression of nuclear genes for components of mitochondrial complex I. Promotes cytokinin-mediated leaf longevity. Involved in the ethylene signaling pathway in an ETR1-dependent manner and in the cytokinin signaling pathway. {ECO:0000269|PubMed:11370868, ECO:0000269|PubMed:11574878, ECO:0000269|PubMed:15282545, ECO:0000269|PubMed:16407152}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006419449.10.0two-component response regulator ARR2
RefseqXP_024047529.10.0two-component response regulator ARR2
SwissprotQ9ZWJ91e-176ARR2_ARATH; Two-component response regulator ARR2
TrEMBLV4S1W30.0V4S1W3_9ROSI; Two-component response regulator
STRINGXP_006488883.10.0(Citrus sinensis)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G16110.11e-164response regulator 2
Publications ? help Back to Top
  1. Takahashi N, et al.
    Cytokinins control endocycle onset by promoting the expression of an APC/C activator in Arabidopsis roots.
    Curr. Biol., 2013. 23(18): p. 1812-7
    [PMID:24035544]
  2. Ge XM, et al.
    Heterotrimeric G protein mediates ethylene-induced stomatal closure via hydrogen peroxide synthesis in Arabidopsis.
    Plant J., 2015. 82(1): p. 138-50
    [PMID:25704455]
  3. Takahashi N,Umeda M
    Cytokinins promote onset of endoreplication by controlling cell cycle machinery.
    Plant Signal Behav, 2014. 9(8): p. e29396
    [PMID:25763620]
  4. Kobayashi K, et al.
    Shoot Removal Induces Chloroplast Development in Roots via Cytokinin Signaling.
    Plant Physiol., 2017. 173(4): p. 2340-2355
    [PMID:28193764]
  5. Arnaud D, et al.
    Cytokinin-Mediated Regulation of Reactive Oxygen Species Homeostasis Modulates Stomatal Immunity in Arabidopsis.
    Plant Cell, 2017. 29(3): p. 543-559
    [PMID:28254779]
  6. Zhang TQ, et al.
    A Two-Step Model for de Novo Activation of WUSCHEL during Plant Shoot Regeneration.
    Plant Cell, 2017. 29(5): p. 1073-1087
    [PMID:28389585]
  7. Meng WJ, et al.
    Type-B ARABIDOPSIS RESPONSE REGULATORs Specify the Shoot Stem Cell Niche by Dual Regulation of WUSCHEL.
    Plant Cell, 2017. 29(6): p. 1357-1372
    [PMID:28576846]
  8. Zhang F,May A,Irish VF
    Type-B ARABIDOPSIS RESPONSE REGULATORs Directly Activate WUSCHEL.
    Trends Plant Sci., 2017. 22(10): p. 815-817
    [PMID:28886911]
  9. Takatsuka H,Higaki T,Umeda M
    Actin Reorganization Triggers Rapid Cell Elongation in Roots.
    Plant Physiol., 2018. 178(3): p. 1130-1141
    [PMID:30185441]