PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Csa14g064560.1

Organism

Camelina sativa

Taxonomic ID

90675

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Camelina

Family

ERF

Protein Properties

Length: 363aa MW: 39986.2 Da PI: 5.1865

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Csa14g064560.1	genome	CSGP	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	64.7	1.9e-20	127	176	2	55
AP2 2 gykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 +y+G+r+++ +g+W+AeIrdp++ +r++lg+f taeeAa+a++aa+++++g Csa14g064560.1 127 QYRGIRQRP-WGKWAAEIRDPRK---GARIWLGTFKTAEEAARAYDAAARRIRG 176 69*****.******954...4***********************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
CDD	cd00018	5.20E-18	127	185	No hit	No description
Gene3D	G3DSA:3.30.730.10	5.1E-33	127	186	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	1.24E-22	127	185	IPR016177	DNA-binding domain
PROSITE profile	PS51032	24.605	127	184	IPR001471	AP2/ERF domain
SMART	SM00380	8.5E-40	127	190	IPR001471	AP2/ERF domain
PRINTS	PR00367	1.1E-11	128	139	IPR001471	AP2/ERF domain
Pfam	PF00847	2.6E-13	128	176	IPR001471	AP2/ERF domain
PRINTS	PR00367	1.1E-11	150	166	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0070483	Biological Process	detection of hypoxia
GO:0005634	Cellular Component	nucleus
GO:0005886	Cellular Component	plasma membrane
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 363 aa Download sequence Send to blast
MCGGAIISDF IPPPRSRRVT SEFIWPDLKK SAKAAKKISK KRSNFFDLDD EFEADFHGFK 60 DDSFIDCDDD DDFDVGDVFA DVKPFVFGST PKPAVSSAPT AAEGSAFGKK VAGGEAEKSG 120 KRKRKNQYRG IRQRPWGKWA AEIRDPRKGA RIWLGTFKTA EEAARAYDAA ARRIRGSKAK 180 VNFPEENPQK RSAAKASLQK PVAKPNPNPS PALVHNPNNN SFEDMCFVEE KHQVNNNNNN 240 NQFGLANSID AGCNGYQYFS SDQGSNSFDC SEFGWSDQAP ITPDISSALI NNNNSPALFF 300 EEANPAKKLK SMDFETPCNN NIEWDASLDF LNEDAVATQD NGANPMDLWS IDEIHSMIGG 360 VF*

Sequence ? help Back to Top

Protein Sequence Length: 363 aa Download sequence Send to blast

MCGGAIISDF IPPPRSRRVT SEFIWPDLKK SAKAAKKISK KRSNFFDLDD EFEADFHGFK  60
DDSFIDCDDD DDFDVGDVFA DVKPFVFGST PKPAVSSAPT AAEGSAFGKK VAGGEAEKSG  120
KRKRKNQYRG IRQRPWGKWA AEIRDPRKGA RIWLGTFKTA EEAARAYDAA ARRIRGSKAK  180
VNFPEENPQK RSAAKASLQK PVAKPNPNPS PALVHNPNNN SFEDMCFVEE KHQVNNNNNN  240
NQFGLANSID AGCNGYQYFS SDQGSNSFDC SEFGWSDQAP ITPDISSALI NNNNSPALFF  300
EEANPAKKLK SMDFETPCNN NIEWDASLDF LNEDAVATQD NGANPMDLWS IDEIHSMIGG  360
VF*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1gcc_A	9e-23	127	184	2	60	ETHYLENE RESPONSIVE ELEMENT BINDING FACTOR 1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor involved in the activation of hypoxic gene expression and in ethylene response. Partially redundant with RAP2-2. Acts as a downstream regulator in the ethylene signaling pathway. {ECO:0000269\|PubMed:22020282, ECO:0000269\|PubMed:22530619}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00204	DAP	Transfer from AT1G53910	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Csa14g064560.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Up-regulated by hypoxia but not by ethylene. {ECO:0000269\|PubMed:22020282}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_010462298.1	0.0	PREDICTED: ethylene-responsive transcription factor RAP2-12-like isoform X1
Refseq	XP_010462299.1	0.0	PREDICTED: ethylene-responsive transcription factor RAP2-12-like isoform X1
Refseq	XP_010462300.1	0.0	PREDICTED: ethylene-responsive transcription factor RAP2-12-like isoform X3
Refseq	XP_019091839.1	0.0	PREDICTED: ethylene-responsive transcription factor RAP2-12-like isoform X2
Refseq	XP_019091840.1	0.0	PREDICTED: ethylene-responsive transcription factor RAP2-12-like isoform X2
Swissprot	Q9SSA8	0.0	RA212_ARATH; Ethylene-responsive transcription factor RAP2-12
TrEMBL	A0A178WE84	0.0	A0A178WE84_ARATH; RAP2.12
STRING	XP_010462298.1	0.0	(Camelina sativa)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM10	28	1650

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G53910.2	1e-169	related to AP2 12

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Kosmacz M, et al. The stability and nuclear localization of the transcription factor RAP2.12 are dynamically regulated by oxygen concentration. Plant Cell Environ., 2015. 38(6): p. 1094-103 [PMID:25438831] Bui LT,Giuntoli B,Kosmacz M,Parlanti S,Licausi F Constitutively expressed ERF-VII transcription factors redundantly activate the core anaerobic response in Arabidopsis thaliana. Plant Sci., 2015. 236: p. 37-43 [PMID:26025519] Gasch P, et al. Redundant ERF-VII Transcription Factors Bind to an Evolutionarily Conserved cis-Motif to Regulate Hypoxia-Responsive Gene Expression in Arabidopsis. Plant Cell, 2016. 28(1): p. 160-80 [PMID:26668304] Gonzali S, et al. Universal stress protein HRU1 mediates ROS homeostasis under anoxia. Nat Plants, 2015. 1: p. 15151 [PMID:27251529] Paul MV, et al. Oxygen Sensing via the Ethylene Response Transcription Factor RAP2.12 Affects Plant Metabolism and Performance under Both Normoxia and Hypoxia. Plant Physiol., 2016. 172(1): p. 141-53 [PMID:27372243] Shahzad Z, et al. A Potassium-Dependent Oxygen Sensing Pathway Regulates Plant Root Hydraulics. Cell, 2016. 167(1): p. 87-98.e14 [PMID:27641502] Yao Y, et al. ETHYLENE RESPONSE FACTOR 74 (ERF74) plays an essential role in controlling a respiratory burst oxidase homolog D (RbohD)-dependent mechanism in response to different stresses in Arabidopsis. New Phytol., 2017. 213(4): p. 1667-1681 [PMID:28164334] Giuntoli B,Licausi F,van Veen H,Perata P Functional Balancing of the Hypoxia Regulators RAP2.12 and HRA1 Takes Place in vivo in Arabidopsis thaliana Plants. Front Plant Sci, 2017. 8: p. 591 [PMID:28487707] Yao Y,Chen X,Wu AM ERF-VII members exhibit synergistic and separate roles in Arabidopsis. Plant Signal Behav, 2017. 12(6): p. e1329073 [PMID:28537474] Eysholdt-Derzsó E,Sauter M Root Bending Is Antagonistically Affected by Hypoxia and ERF-Mediated Transcription via Auxin Signaling. Plant Physiol., 2017. 175(1): p. 412-423 [PMID:28698356] Giuntoli B, et al. Age-dependent regulation of ERF-VII transcription factor activity in Arabidopsis thaliana. Plant Cell Environ., 2017. 40(10): p. 2333-2346 [PMID:28741696]