PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Csa07g065130.1

Organism

Camelina sativa

Taxonomic ID

90675

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Camelina

Family

bHLH

Protein Properties

Length: 602aa MW: 67088.7 Da PI: 4.8926

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Csa07g065130.1	genome	CSGP	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	40.9	3.7e-13	410	456	4	55
HHHHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHHH CS HLH 4 ahnerErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksLq 55 +h E++RR+++N++f +Lr+++P+ + K +K++iL ++ Y+++Lq Csa07g065130.1 410 NHALCEKKRREKLNERFMTLRSIIPSiS------KIDKVSILDDTIGYLQELQ 456 79999*******************66......****************9 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF14215	7.3E-54	18	207	IPR025610	Transcription factor MYC/MYB N-terminal
PROSITE profile	PS50888	15.961	406	455	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	1.2E-10	410	456	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	7.81E-14	410	460	No hit	No description
Gene3D	G3DSA:4.10.280.10	7.9E-17	410	473	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	1.7E-17	410	474	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	8.7E-16	412	461	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 602 aa Download sequence Send to blast
MNEETMTTVE NRTVLGNLKK QLAVSVRNIQ WSYGIFWSVS ASQPGVLEWG DGYYNGDIKT 60 RKTIQAAEVK VDQLGLERSE QLRELYESLS LAESSASGGS QVTRRASAAA LSPEDLTDTE 120 WYYLVCMSFV FNIGEGIPGG ALSNGEPIWL CNAQTADSKV FTRSLLAKSA SLQTVVCFPF 180 LGGVLEIGTT EHITEDLNVI QCVKTMFLEA PPYATISTRS DYQEVFDPLS DDKYIPVFAT 240 EAFPTASTSE FEQEPEDHDS FINDGGASQV QSWKFVGEEL SNCVHQSLNS SDCVSQTFVG 300 TTGRVACDPR KGRVQRLGQI QEQSNHVNMD DDVHYQGVIS TIFKTTHQLI LGPQFQNFDK 360 RSSFTRWKRS SSVKTSVEKS QKMIKKILFE VPLMNKKEGL LPDTPEETGN HALCEKKRRE 420 KLNERFMTLR SIIPSISKID KVSILDDTIG YLQELQKRVQ ELESCRESAD TETRMTMMKR 480 KKPEDEDERA SANCMNSKRK GSDVNVGEDE PVDTGYAGLT DNLRISSLGN EVVIELRCAW 540 REGILLEIMD VISDLNLDSH SVQSSTGDGL LCLNVNCKHK GKKMATTGMI QEALQRVAWI 600 C*

Sequence ? help Back to Top

Protein Sequence Length: 602 aa Download sequence Send to blast

MNEETMTTVE NRTVLGNLKK QLAVSVRNIQ WSYGIFWSVS ASQPGVLEWG DGYYNGDIKT  60
RKTIQAAEVK VDQLGLERSE QLRELYESLS LAESSASGGS QVTRRASAAA LSPEDLTDTE  120
WYYLVCMSFV FNIGEGIPGG ALSNGEPIWL CNAQTADSKV FTRSLLAKSA SLQTVVCFPF  180
LGGVLEIGTT EHITEDLNVI QCVKTMFLEA PPYATISTRS DYQEVFDPLS DDKYIPVFAT  240
EAFPTASTSE FEQEPEDHDS FINDGGASQV QSWKFVGEEL SNCVHQSLNS SDCVSQTFVG  300
TTGRVACDPR KGRVQRLGQI QEQSNHVNMD DDVHYQGVIS TIFKTTHQLI LGPQFQNFDK  360
RSSFTRWKRS SSVKTSVEKS QKMIKKILFE VPLMNKKEGL LPDTPEETGN HALCEKKRRE  420
KLNERFMTLR SIIPSISKID KVSILDDTIG YLQELQKRVQ ELESCRESAD TETRMTMMKR  480
KKPEDEDERA SANCMNSKRK GSDVNVGEDE PVDTGYAGLT DNLRISSLGN EVVIELRCAW  540
REGILLEIMD VISDLNLDSH SVQSSTGDGL LCLNVNCKHK GKKMATTGMI QEALQRVAWI  600
C*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
4rqw_A	7e-16	31	207	24	192	Transcription factor MYC3
4rqw_B	7e-16	31	207	24	192	Transcription factor MYC3
4rs9_A	7e-16	31	207	24	192	Transcription factor MYC3
4yz6_A	7e-16	31	207	24	192	Transcription factor MYC3
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	415	420	KKRREK

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator, when associated with MYB75/PAP1, MYB90/PAP2 or TT2. Involved in epidermal cell fate specification. Regulates negatively stomata formation but promotes trichome formation. Together with MYB66/WER, promotes the formation of non-hair cells in root epidermis cells in the N position. Whereas together with CPC, promotes the formation of hair cells in root epidermis cells in the H position by inhibiting non-hair cell formation. Seems also to play a role in the activation of anthocyanin biosynthesis, probably together with MYB75/PAP1. Involved in seed mucilage production. Activates the transcription of GL2. {ECO:0000269\|PubMed:12917293, ECO:0000269\|PubMed:12956536, ECO:0000269\|PubMed:14627722, ECO:0000269\|PubMed:15361138, ECO:0000269\|PubMed:15590742}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Csa07g065130.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By UV treatment. Negatively regulated by MYB66/WER, GL3 and BHLH2 in the developing non-hair cells, and positively regulated by CPC and TRY in the developing hair cells. {ECO:0000269\|PubMed:12679534, ECO:0000269\|PubMed:15590742}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AF027732	0.0	AF027732.1 Arabidopsis thaliana bHLH protein (Atmyc-2) mRNA, complete sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_010418394.1	0.0	PREDICTED: transcription factor EGL1-like isoform X1
Swissprot	Q9CAD0	0.0	EGL1_ARATH; Transcription factor EGL1
TrEMBL	D7KTF4	0.0	D7KTF4_ARALL; Uncharacterized protein
STRING	XP_010418395.1	0.0	(Camelina sativa)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM2592	28	67

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G63650.3	0.0	bHLH family protein

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Liu Z,Shi MZ,Xie DY Regulation of anthocyanin biosynthesis in Arabidopsis thaliana red pap1-D cells metabolically programmed by auxins. Planta, 2014. 239(4): p. 765-81 [PMID:24370633] Nayidu NK, et al. Comparison of five major trichome regulatory genes in Brassica villosa with orthologues within the Brassicaceae. PLoS ONE, 2014. 9(4): p. e95877 [PMID:24755905] Cheng Y, et al. Brassinosteroids control root epidermal cell fate via direct regulation of a MYB-bHLH-WD40 complex by GSK3-like kinases. Elife, 2018. [PMID:24771765] Ranocha P,Francoz E,Burlat V,Dunand C Expression of PRX36, PMEI6 and SBT1.7 is controlled by complex transcription factor regulatory networks for proper seed coat mucilage extrusion. Plant Signal Behav, 2014. 9(11): p. e977734 [PMID:25531128] Nemie-Feyissa D,Heidari B,Blaise M,Lillo C Analysis of interactions between heterologously produced bHLH and MYB proteins that regulate anthocyanin biosynthesis: quantitative interaction kinetics by Microscale Thermophoresis. Phytochemistry, 2015. 111: p. 21-6 [PMID:25659750] Kwak SH,Song SK,Lee MM,Schiefelbein J TORNADO1 regulates root epidermal patterning through the WEREWOLF pathway in Arabidopsis thaliana. Plant Signal Behav, 2015. 10(12): p. e1103407 [PMID:26451798] Dai X, et al. A single amino acid substitution in the R3 domain of GLABRA1 leads to inhibition of trichome formation in Arabidopsis without affecting its interaction with GLABRA3. Plant Cell Environ., 2016. 39(4): p. 897-907 [PMID:26667588] Friede A, et al. The Second Intron Is Essential for the Transcriptional Control of the Arabidopsis thaliana GLABRA3 Gene in Leaves. Front Plant Sci, 2017. 8: p. 1382 [PMID:28848584] Feng K, et al. An R2R3-MYB transcription factor, OjMYB1, functions in anthocyanin biosynthesis in Oenanthe javanica. Planta, 2018. 247(2): p. 301-315 [PMID:28965159] Wen J, et al. The C-terminal domains of Arabidopsis GL3/EGL3/TT8 interact with JAZ proteins and mediate dimeric interactions. Plant Signal Behav, 2018. 13(1): p. e1422460 [PMID:29293407]