PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | XP_012572831.1 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Cicereae; Cicer
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Family | E2F/DP | ||||||||
Protein Properties | Length: 458aa MW: 50767.4 Da PI: 4.5011 | ||||||||
Description | E2F/DP family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | E2F_TDP | 86.6 | 1.8e-27 | 139 | 204 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL+llt+kf++l++++e+gi++ln++a++L +v ++RRiYDi+NVLe+++liekk kn+i+wkg XP_012572831.1 139 RYDSSLGLLTKKFIHLIKQAEDGILDLNKAADTL---EV--QKRRIYDITNVLEGIGLIEKKLKNRIQWKG 204 6899******************************...99..****************************98 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Gene3D | G3DSA:1.10.10.10 | 3.8E-29 | 137 | 206 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SuperFamily | SSF46785 | 3.26E-17 | 139 | 202 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 4.4E-35 | 139 | 204 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Pfam | PF02319 | 9.8E-25 | 141 | 204 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
CDD | cd14660 | 1.21E-48 | 215 | 321 | No hit | No description |
SuperFamily | SSF144074 | 4.45E-34 | 218 | 321 | No hit | No description |
Pfam | PF16421 | 2.3E-34 | 220 | 319 | IPR032198 | E2F transcription factor, CC-MB domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0008284 | Biological Process | positive regulation of cell proliferation | ||||
GO:0009733 | Biological Process | response to auxin | ||||
GO:0010090 | Biological Process | trichome morphogenesis | ||||
GO:0045893 | Biological Process | positive regulation of transcription, DNA-templated | ||||
GO:0051302 | Biological Process | regulation of cell division | ||||
GO:0051446 | Biological Process | positive regulation of meiotic cell cycle | ||||
GO:0005634 | Cellular Component | nucleus | ||||
GO:0005667 | Cellular Component | transcription factor complex | ||||
GO:0005737 | Cellular Component | cytoplasm | ||||
GO:0003677 | Molecular Function | DNA binding | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 458 aa Download sequence Send to blast |
MSANRAPPAA SSSNPPDQIM QSMKRQLPFS SMKPPFVASG DYHRFGPNNR RNLDQETEAI 60 VVKTPQLKRK SETADFEADS GDRMTPESTE AANSPSQTPA SGKTGKAGKS SRLTKCNRSG 120 TQTPGSNIGN NLTPAGPCRY DSSLGLLTKK FIHLIKQAED GILDLNKAAD TLEVQKRRIY 180 DITNVLEGIG LIEKKLKNRI QWKGLDVSKP GEADDSFASL QAEVENLTIE ERRLDEQIRE 240 MQERLRELSE DENNEKLLFV TEEDIKNLPC FQNETLIAIK APHGTTLEVP DPDEAVDYPQ 300 RRYRIVLRST MGPIDVYLVS QFEEKFEEIN GVDVAPKFPS SPEVDKQQST LVPEDKGKEV 360 EVQGQDGEGP SSDFTNSHDF VSGIMKIVPS DVASDADYWL LSDADVSITD MWRTEPTVEW 420 NELNKLQEDY CTAPEHTTTP SHPSNIGEVS SASNPPDG |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
1cf7_A | 4e-27 | 134 | 205 | 2 | 74 | PROTEIN (TRANSCRIPTION FACTOR E2F-4) |
Search in ModeBase |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Involved in the control of cell-cycle progression from G1 to S phase and from G2 to M phase. Stimulates cell proliferation and delays differentiation. Represses cell enlargement and endoreduplication in auxin-free conditions. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015}. |
Cis-element ? help Back to Top | |
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Source | Link |
PlantRegMap | XP_012572831.1 |
Regulation -- Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | INDUCTION: Up-regulated by light and by auxin. May be up-regulated by E2FA. {ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:18424613}. |
Regulation -- PlantRegMap ? help Back to Top | ||||||
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Source | Upstream Regulator | Target Gene | ||||
PlantRegMap | Retrieve | - |
Annotation -- Nucleotide ? help Back to Top | ||||||
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Source | Hit ID | E-value | Description | |||
GenBank | BT052455 | 0.0 | BT052455.1 Medicago truncatula clone MTYFD_FE_FF_FG1G-O-10 unknown mRNA. |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_012572831.1 | 0.0 | transcription factor E2FB isoform X2 | ||||
Swissprot | Q9FV71 | 1e-158 | E2FB_ARATH; Transcription factor E2FB | ||||
TrEMBL | A0A1S3ED02 | 0.0 | A0A1S3ED02_CICAR; transcription factor E2FB isoform X2 | ||||
STRING | XP_004506213.1 | 0.0 | (Cicer arietinum) |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT5G22220.2 | 1e-160 | E2F transcription factor 1 |
Publications ? help Back to Top | |||
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