PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_012571326.1
Organism
Cicer arietinum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Cicereae; Cicer
Family ARF
Protein Properties Length: 853aa    MW: 94475 Da    PI: 6.391
Description ARF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_012571326.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B372.64.8e-23130231199
                     EEEE-..-HHHHTT-EE--HHH.HTT.......---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHHHHHHT--TT-EEEEEE-SSS CS
              B3   1 ffkvltpsdvlksgrlvlpkkfaeeh.......ggkkeesktltledesgrsWevkliyrkksgryvltkGWkeFvkangLkegDfvvFkldgrs 88 
                     f+k+lt sd++++g +++p++ ae+        +++++  ++l+ +d++  +W++++i+r++++r++lt+GW+ Fv+a++L +gD+v+F   +++
  XP_012571326.1 130 FCKTLTASDTSTHGGFSVPRRAAEKVfppldfsQQPPA--QELIARDLHDVEWKFRHIFRGQPKRHLLTTGWSIFVSAKRLVAGDSVLFI--WNE 220
                     99*****************************8544444..48************************************************..889 PP

                     EE..EEEEE-S CS
              B3  89 efelvvkvfrk 99 
                     + +l+++++r+
  XP_012571326.1 221 KNQLLLGIRRA 231
                     9999****997 PP
2Auxin_resp1187.8e-39256339183
      Auxin_resp   1 aahaastksvFevvYnPrastseFvvkvekvekalk.vkvsvGmRfkmafetedsserrlsGtvvgvsdldpvrWpnSkWrsLk 83 
                     aahaa+t+s F+v+YnPras+seFv++++k+ ka++ +++svGmRf+m fete+ss rr++Gt++g+sdld vrWpnS+Wrs+k
  XP_012571326.1 256 AAHAAATNSCFTVFYNPRASPSEFVIPLSKYIKAVYhTRISVGMRFRMLFETEESSVRRYMGTITGISDLDAVRWPNSHWRSVK 339
                     79*********************************9789******************************************985 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019363.14E-49114259IPR015300DNA-binding pseudobarrel domain
Gene3DG3DSA:2.40.330.104.6E-41123245IPR015300DNA-binding pseudobarrel domain
CDDcd100172.14E-21129230No hitNo description
SMARTSM010196.4E-24130232IPR003340B3 DNA binding domain
PROSITE profilePS5086312.308130232IPR003340B3 DNA binding domain
PfamPF023622.5E-21130231IPR003340B3 DNA binding domain
PfamPF065072.2E-34256339IPR010525Auxin response factor
PfamPF023093.8E-7722810IPR033389AUX/IAA domain
SuperFamilySSF542771.37E-6724800No hitNo description
PROSITE profilePS5174524.119726810IPR000270PB1 domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009733Biological Processresponse to auxin
GO:0009908Biological Processflower development
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0005515Molecular Functionprotein binding
Sequence ? help Back to Top
Protein Sequence    Length: 853 aa     Download sequence    Send to blast
MKLSTSGLGQ QGHEGGGGEK KCLNSELWHA CAGPLVSLPT AGTRVVYFPQ GHSEQVSATT  60
NREIDGHIPN YPSLPPQLVC QLHNVTMHAD VETDEVYAQM TLQPLTPDEQ KDTFLPMELG  120
IPSKQPSNYF CKTLTASDTS THGGFSVPRR AAEKVFPPLD FSQQPPAQEL IARDLHDVEW  180
KFRHIFRGQP KRHLLTTGWS IFVSAKRLVA GDSVLFIWNE KNQLLLGIRR ANRPQTVMPS  240
SVLSSDSMHI GLLAAAAHAA ATNSCFTVFY NPRASPSEFV IPLSKYIKAV YHTRISVGMR  300
FRMLFETEES SVRRYMGTIT GISDLDAVRW PNSHWRSVKV GWDESTAGER QPRVSLWEIE  360
PLTTFPMYPS LFPVRLKRPW HPGTSSLLDG RDEAGNGLMW MRGGPADQGL NSLNFQGAAG  420
LLPWMQQRLD PSLLGNDQNQ QYQAMLAAGL QNMGSGYIMR PQMMNFQQQP IHYHLQSGNN  480
NSPLQLQQPQ AVQHSGSSNM LQPQQAQLLT ENLSQHLLQK PNNNQEVQAQ QQQHHTYQDT  540
LLIQNDQLHQ RQPSNVPSPS YSKPDFLDSN MKFTASVPPG QNMLSSLCSE GTGNLLNLSS  600
LSRGGQSLLT EQLPQQSWTP KYADMQVNAF GSTMSHAQYS GKDSAMVTPH CDSDAQNRTL  660
SGVNIDSSGL LLPTTVPGYT TSSADTDAST MQLGESGFQG SLYACMQDSS SFLHNAGQID  720
PQNQNPTFVK VYKLGSVGRS LDISRFSSYR ELREELGQMF GIEGKLEDPL RSGWQLVFVD  780
RENDVLLLGD DPWESFVNNV WYIKILSPED IQKMGEQAVE THALGSGQRL SDSGADSHHV  840
VSGQPPSIGS LEY
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4ldu_A1e-1591736045388Auxin response factor 5
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtAuxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Seems to act as transcriptional activator. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. Regulates both stamen and gynoecium maturation. Promotes jasmonic acid production. Partially redundant with ARF6. Involved in fruit initiation. Acts as an inhibitor to stop further carpel development in the absence of fertilization and the generation of signals required to initiate fruit and seed development. {ECO:0000269|PubMed:12036261, ECO:0000269|PubMed:16107481, ECO:0000269|PubMed:16829592}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00033PBMTransfer from AT5G37020Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapXP_012571326.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Repressed by miR167. {ECO:0000269|PubMed:17021043}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAC1515290.0AC151529.20 Medicago truncatula clone mth2-7n23, complete sequence.
GenBankCU4682440.0CU468244.3 M.truncatula DNA sequence from clone MTH2-16M9 on chromosome 3, complete sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_012571326.10.0auxin response factor 8
RefseqXP_012571327.10.0auxin response factor 8
SwissprotQ9FGV10.0ARFH_ARATH; Auxin response factor 8
TrEMBLA0A1S3E6850.0A0A1S3E685_CICAR; Auxin response factor
STRINGXP_004500428.10.0(Cicer arietinum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF49582850
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G37020.10.0auxin response factor 8
Publications ? help Back to Top
  1. Liu N, et al.
    Down-regulation of AUXIN RESPONSE FACTORS 6 and 8 by microRNA 167 leads to floral development defects and female sterility in tomato.
    J. Exp. Bot., 2014. 65(9): p. 2507-20
    [PMID:24723401]
  2. Minato N, et al.
    The phytoplasmal virulence factor TENGU causes plant sterility by downregulating of the jasmonic acid and auxin pathways.
    Sci Rep, 2014. 4: p. 7399
    [PMID:25492247]
  3. Ortega-Amaro MA, et al.
    Overexpression of AtGRDP2, a novel glycine-rich domain protein, accelerates plant growth and improves stress tolerance.
    Front Plant Sci, 2014. 5: p. 782
    [PMID:25653657]
  4. Wang Y, et al.
    MicroRNA167-Directed Regulation of the Auxin Response Factors GmARF8a and GmARF8b Is Required for Soybean Nodulation and Lateral Root Development.
    Plant Physiol., 2015. 168(3): p. 984-99
    [PMID:25941314]
  5. Barik S, et al.
    Coevolution Pattern and Functional Conservation or Divergence of miR167s and their targets across Diverse Plant Species.
    Sci Rep, 2015. 5: p. 14611
    [PMID:26459056]
  6. Pashkovskiy PP,Kartashov AV,Zlobin IE,Pogosyan SI,Kuznetsov VV
    Blue light alters miR167 expression and microRNA-targeted auxin response factor genes in Arabidopsis thaliana plants.
    Plant Physiol. Biochem., 2016. 104: p. 146-54
    [PMID:27031426]
  7. Mlotshwa S,Pruss GJ,MacArthur JL,Reed JW,Vance V
    Developmental Defects Mediated by the P1/HC-Pro Potyviral Silencing Suppressor Are Not Due to Misregulation of AUXIN RESPONSE FACTOR 8.
    Plant Physiol., 2016. 172(3): p. 1853-1861
    [PMID:27688620]
  8. Wójcikowska B,Gaj MD
    Expression profiling of AUXIN RESPONSE FACTOR genes during somatic embryogenesis induction in Arabidopsis.
    Plant Cell Rep., 2017. 36(6): p. 843-858
    [PMID:28255787]
  9. Zhang GZ, et al.
    Ectopic expression of UGT84A2 delayed flowering by indole-3-butyric acid-mediated transcriptional repression of ARF6 and ARF8 genes in Arabidopsis.
    Plant Cell Rep., 2017. 36(12): p. 1995-2006
    [PMID:29027578]
  10. Zheng K, et al.
    Involvement of PACLOBUTRAZOL RESISTANCE6/KIDARI, an Atypical bHLH Transcription Factor, in Auxin Responses in Arabidopsis.
    Front Plant Sci, 2017. 8: p. 1813
    [PMID:29114256]
  11. Liu Z, et al.
    ARF2-ARF4 and ARF5 are Essential for Female and Male Gametophyte Development in Arabidopsis.
    Plant Cell Physiol., 2018. 59(1): p. 179-189
    [PMID:29145642]
  12. Ghelli R, et al.
    A Newly Identified Flower-Specific Splice Variant of AUXIN RESPONSE FACTOR8 Regulates Stamen Elongation and Endothecium Lignification in Arabidopsis.
    Plant Cell, 2018. 30(3): p. 620-637
    [PMID:29514943]