PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

XP_004511162.1

Organism

Cicer arietinum

Taxonomic ID

3827

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Cicereae; Cicer

Family

AP2

Protein Properties

Length: 422aa MW: 47705.6 Da PI: 5.8529

Description

AP2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_004511162.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	50.7	4.5e-16	59	118	1	55
AP2 1 sgykGVrwdkkrgrWvAeIrd.pseng...kr.krfslgkfgtaeeAakaaiaarkkleg 55 s y+GV++++++gr++A+++d s+n+ k+ ++++lg ++t+e Aa+ ++ a++k++g XP_004511162.1 59 SIYRGVTRHRWTGRFEAHLWDkSSWNNiqsKKgRQVYLGAYDTEEAAARTYDLAALKYWG 118 57*****************777799987557***********************98 PP
2	AP2	52.4	1.3e-16	161	212	1	55
AP2 1 sgykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 s+y+GV +++ +grW+A+I ++ +k+ +lg++ t eeAaka++ a+ + +g XP_004511162.1 161 SKYRGVARHHHNGRWEARIGRVCG---NKYLYLGTYKTQEEAAKAYDIAAIEHRG 212 89**99*******99644...4********************99887 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
CDD	cd00018	3.09E-23	59	127	No hit	No description
SuperFamily	SSF54171	4.58E-17	59	128	IPR016177	DNA-binding domain
Pfam	PF00847	1.8E-12	59	118	IPR001471	AP2/ERF domain
SMART	SM00380	1.2E-26	60	132	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	20.956	60	126	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	1.2E-16	60	126	IPR001471	AP2/ERF domain
PRINTS	PR00367	2.0E-5	61	72	IPR001471	AP2/ERF domain
Pfam	PF00847	4.5E-11	161	211	IPR001471	AP2/ERF domain
CDD	cd00018	5.94E-25	161	222	No hit	No description
SuperFamily	SSF54171	5.23E-17	161	222	IPR016177	DNA-binding domain
PROSITE profile	PS51032	18.017	162	220	IPR001471	AP2/ERF domain
SMART	SM00380	4.0E-26	162	226	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	1.5E-17	162	220	IPR001471	AP2/ERF domain
PRINTS	PR00367	2.0E-5	202	222	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006110	Biological Process	regulation of glycolytic process
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0009744	Biological Process	response to sucrose
GO:0019432	Biological Process	triglyceride biosynthetic process
GO:1901959	Biological Process	positive regulation of cutin biosynthetic process
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 422 aa Download sequence Send to blast
MKRSPPSSSS SSSSSVGFET QIQSEKKRGA KNPKKNLSVK SQNCKQKKNQ TNGGSRRSSI 60 YRGVTRHRWT GRFEAHLWDK SSWNNIQSKK GRQVYLGAYD TEEAAARTYD LAALKYWGKD 120 ATLNFPIETY GKEVEEMDKI SREEYLASLR RQSSGFSRGI SKYRGVARHH HNGRWEARIG 180 RVCGNKYLYL GTYKTQEEAA KAYDIAAIEH RGLNAVTNFD ISNYINKFKN KIDESEQTQP 240 QTTTIEIVQN SSDSEVAQEE QQQITITTTP PQEILEKIEV PMLHQQQQQQ HVPPIEQEHT 300 IVNVMDHYLE QDLPSSFMFQ DSDELALSNA EIDLMQIFDG SSFEDNIDLW FNTDPGFDSD 360 INISEVLEGI NCGGLLNGDA GNNMIVDGNN NNNIKNKENK EILSLNSSSS SSLSSTTTID 420 YL

Sequence ? help Back to Top

Protein Sequence Length: 422 aa Download sequence Send to blast

MKRSPPSSSS SSSSSVGFET QIQSEKKRGA KNPKKNLSVK SQNCKQKKNQ TNGGSRRSSI  60
YRGVTRHRWT GRFEAHLWDK SSWNNIQSKK GRQVYLGAYD TEEAAARTYD LAALKYWGKD  120
ATLNFPIETY GKEVEEMDKI SREEYLASLR RQSSGFSRGI SKYRGVARHH HNGRWEARIG  180
RVCGNKYLYL GTYKTQEEAA KAYDIAAIEH RGLNAVTNFD ISNYINKFKN KIDESEQTQP  240
QTTTIEIVQN SSDSEVAQEE QQQITITTTP PQEILEKIEV PMLHQQQQQQ HVPPIEQEHT  300
IVNVMDHYLE QDLPSSFMFQ DSDELALSNA EIDLMQIFDG SSFEDNIDLW FNTDPGFDSD  360
INISEVLEGI NCGGLLNGDA GNNMIVDGNN NNNIKNKENK EILSLNSSSS SSLSSTTTID  420
YL

Functional Description ? help Back to Top
Source	Description
UniProt	May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). Transcriptional activator involved in the activation of a subset of sugar-responsive genes and the control of carbon flow from sucrose import to oil accumulation in developing seeds. Binds to the GCC-box pathogenesis-related promoter element. Promotes sugar uptake and seed oil accumulation by glycolysis. Required for embryo development, seed germination and, indirectly, for seedling establishment. Negative regulator of the ABA-mediated germination inhibition. {ECO:0000250, ECO:0000269\|PubMed:12084821, ECO:0000269\|PubMed:15500472, ECO:0000269\|PubMed:15753106, ECO:0000269\|PubMed:16553903, ECO:0000269\|PubMed:16632590, ECO:0000269\|PubMed:9733529}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	XP_004511162.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Transiantly in leaves by sucrose, but not by abscisic acid (ABA). {ECO:0000269\|PubMed:15753106}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_004511162.1	0.0	AP2-like ethylene-responsive transcription factor At1g79700
Swissprot	Q6X5Y6	1e-103	WRI1_ARATH; Ethylene-responsive transcription factor WRI1
TrEMBL	A0A1S2YWS0	0.0	A0A1S2YWS0_CICAR; AP2-like ethylene-responsive transcription factor At1g79700
STRING	XP_004511162.1	0.0	(Cicer arietinum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF9859	32	41

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G54320.3	1e-103	AP2 family protein

Publications ? help Back to Top
Kim HU, et al. Ectopic overexpression of castor bean LEAFY COTYLEDON2 (LEC2) in Arabidopsis triggers the expression of genes that encode regulators of seed maturation and oil body proteins in vegetative tissues. FEBS Open Bio, 2013. 4: p. 25-32 [PMID:24363987] Wu XL,Liu ZH,Hu ZH,Huang RZ BnWRI1 coordinates fatty acid biosynthesis and photosynthesis pathways during oil accumulation in rapeseed. J Integr Plant Biol, 2014. 56(6): p. 582-93 [PMID:24393360] Shigematsu H, et al. Structural characterization of the mechanosensitive channel candidate MCA2 from Arabidopsis thaliana. PLoS ONE, 2014. 9(1): p. e87724 [PMID:24475319] Kim HU, et al. Senescence-inducible LEC2 enhances triacylglycerol accumulation in leaves without negatively affecting plant growth. Plant Biotechnol. J., 2015. 13(9): p. 1346-59 [PMID:25790072] Grimberg Å,Carlsson AS,Marttila S,Bhalerao R,Hofvander P Transcriptional transitions in Nicotiana benthamiana leaves upon induction of oil synthesis by WRINKLED1 homologs from diverse species and tissues. BMC Plant Biol., 2015. 15: p. 192 [PMID:26253704] Kanai M,Mano S,Kondo M,Hayashi M,Nishimura M Extension of oil biosynthesis during the mid-phase of seed development enhances oil content in Arabidopsis seeds. Plant Biotechnol. J., 2016. 14(5): p. 1241-50 [PMID:26503031] Li Q, et al. Wrinkled1 Accelerates Flowering and Regulates Lipid Homeostasis between Oil Accumulation and Membrane Lipid Anabolism in Brassica napus. Front Plant Sci, 2015. 6: p. 1015 [PMID:26635841] Hofvander P, et al. Potato tuber expression of Arabidopsis WRINKLED1 increase triacylglycerol and membrane lipids while affecting central carbohydrate metabolism. Plant Biotechnol. J., 2016. 14(9): p. 1883-98 [PMID:26914183] Shen SL, et al. CitAP2.10 activation of the terpene synthase CsTPS1 is associated with the synthesis of (+)-valencene in 'Newhall' orange. J. Exp. Bot., 2016. 67(14): p. 4105-15 [PMID:27194737] Adhikari ND,Bates PD,Browse J WRINKLED1 Rescues Feedback Inhibition of Fatty Acid Synthesis in Hydroxylase-Expressing Seeds. Plant Physiol., 2016. 171(1): p. 179-91 [PMID:27208047] Kim MJ,Jang IC,Chua NH The Mediator Complex MED15 Subunit Mediates Activation of Downstream Lipid-Related Genes by the WRINKLED1 Transcription Factor. Plant Physiol., 2016. 171(3): p. 1951-64 [PMID:27246098] Bhattacharya S,Das N,Maiti MK Cumulative effect of heterologous AtWRI1 gene expression and endogenous BjAGPase gene silencing increases seed lipid content in Indian mustard Brassica juncea. Plant Physiol. Biochem., 2016. 107: p. 204-213 [PMID:27314514] Ma W, et al. 14-3-3 protein mediates plant seed oil biosynthesis through interaction with AtWRI1. Plant J., 2016. 88(2): p. 228-235 [PMID:27322486] Li D, et al. MYB89 Transcription Factor Represses Seed Oil Accumulation. Plant Physiol., 2017. 173(2): p. 1211-1225 [PMID:27932421] Ivarson E, et al. Effects of Overexpression of WRI1 and Hemoglobin Genes on the Seed Oil Content of Lepidium campestre. Front Plant Sci, 2016. 7: p. 2032 [PMID:28119714] An D, et al. Expression of Camelina WRINKLED1 Isoforms Rescue the Seed Phenotype of the Arabidopsis wri1 Mutant and Increase the Triacylglycerol Content in Tobacco Leaves. Front Plant Sci, 2017. 8: p. 34 [PMID:28174580] Zhai Z,Liu H,Shanklin J Phosphorylation of WRINKLED1 by KIN10 Results in Its Proteasomal Degradation, Providing a Link between Energy Homeostasis and Lipid Biosynthesis. Plant Cell, 2017. 29(4): p. 871-889 [PMID:28314829] Jin J, et al. Transcriptome and functional analysis reveals hybrid vigor for oil biosynthesis in oil palm. Sci Rep, 2017. 7(1): p. 439 [PMID:28348403] Kong Q, et al. The Arabidopsis WRINKLED1 transcription factor affects auxin homeostasis in roots. J. Exp. Bot., 2017. 68(16): p. 4627-4634 [PMID:28981783] Kang NK, et al. Increased lipid production by heterologous expression of AtWRI1 transcription factor in Nannochloropsis salina. Biotechnol Biofuels, 2017. 10: p. 231 [PMID:29046718] Pellaud S, et al. WRINKLED1 and ACYL-COA:DIACYLGLYCEROL ACYLTRANSFERASE1 regulate tocochromanol metabolism in Arabidopsis. New Phytol., 2018. 217(1): p. 245-260 [PMID:29105089] Hanano A,Almousally I,Shaban M,Murphy DJ Arabidopsis plants exposed to dioxin result in a WRINKLED seed phenotype due to 20S proteasomal degradation of WRI1. J. Exp. Bot., 2018. 69(7): p. 1781-1794 [PMID:29394403]