PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | XP_004508820.1 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Cicereae; Cicer
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Family | E2F/DP | ||||||||
Protein Properties | Length: 384aa MW: 43445.3 Da PI: 8.7799 | ||||||||
Description | E2F/DP family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | E2F_TDP | 75.4 | 5.7e-24 | 17 | 82 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 rk+ksL+ll+++fl+l+++ + + l+++a++L v +rRRiYDi+NVLe+++++++k+kn+++wkg XP_004508820.1 17 RKQKSLGLLCTNFLSLYNRDNVHLIGLDDAATRL---GV--ERRRIYDIVNVLESIGVLARKAKNQYTWKG 82 79*****************999************...**..****************************98 PP | |||||||
2 | E2F_TDP | 76.3 | 3e-24 | 153 | 233 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 r+eksL lltq+f+kl+ +s+ ++++l+++a+ L+ + +++k+RR+YDi+NVL+++nliek ++k+++rw g XP_004508820.1 153 RREKSLALLTQNFVKLFVCSNVEMISLDDAARLLLGDaynssTMRTKVRRLYDIANVLTSMNLIEKthttdTRKPAFRWLG 233 689*******************************************************************99*******87 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Gene3D | G3DSA:1.10.10.10 | 6.1E-26 | 13 | 83 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SuperFamily | SSF46785 | 1.47E-16 | 16 | 80 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 1.6E-28 | 17 | 82 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Pfam | PF02319 | 1.6E-20 | 18 | 82 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Gene3D | G3DSA:1.10.10.10 | 2.0E-23 | 150 | 235 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 1.9E-29 | 153 | 233 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Pfam | PF02319 | 2.0E-19 | 155 | 233 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
SuperFamily | SSF46785 | 2.04E-13 | 155 | 234 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0006355 | Biological Process | regulation of transcription, DNA-templated | ||||
GO:0032876 | Biological Process | negative regulation of DNA endoreduplication | ||||
GO:0005634 | Cellular Component | nucleus | ||||
GO:0005667 | Cellular Component | transcription factor complex | ||||
GO:0003677 | Molecular Function | DNA binding | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 384 aa Download sequence Send to blast |
MASSSDPPSS RHHTYNRKQK SLGLLCTNFL SLYNRDNVHL IGLDDAATRL GVERRRIYDI 60 VNVLESIGVL ARKAKNQYTW KGFAAIPVAL QELKEEGLWN NLNSHEAGNE GGNEDAKVSD 120 EDDEEESLSQ PTGSQSDSLN PNSTVPRSLK NDRREKSLAL LTQNFVKLFV CSNVEMISLD 180 DAARLLLGDA YNSSTMRTKV RRLYDIANVL TSMNLIEKTH TTDTRKPAFR WLGLKGKTWN 240 ESIYNSNQNE SRKRAFGNDV TNISFTRSNR TDFFMSGDFS QNIKKQKTQE NDSGLCQEDK 300 SNMKQGIKQA SSNYQFGPFA PAFVSKAGNS ENSKVKQAHD WESLATAHCP QYQNQALKDL 360 YSHYMEAWKS WYNEVAGKRQ TQVL |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
4yo2_A | 4e-38 | 16 | 225 | 3 | 228 | Transcription factor E2F8 |
Search in ModeBase |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Inhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}. |
Binding Motif ? help Back to Top | |||
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Motif ID | Method | Source | Motif file |
MP00397 | DAP | Transfer from AT3G48160 | Download |
Cis-element ? help Back to Top | |
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Source | Link |
PlantRegMap | XP_004508820.1 |
Regulation -- PlantRegMap ? help Back to Top | ||||||
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Source | Upstream Regulator | Target Gene | ||||
PlantRegMap | - | Retrieve |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_004508820.1 | 0.0 | E2F transcription factor-like E2FE isoform X1 | ||||
Swissprot | Q8LSZ4 | 1e-127 | E2FE_ARATH; E2F transcription factor-like E2FE | ||||
TrEMBL | A0A1S2YRL5 | 0.0 | A0A1S2YRL5_CICAR; E2F transcription factor-like E2FE isoform X1 | ||||
STRING | XP_004508820.1 | 0.0 | (Cicer arietinum) |
Orthologous Group ? help Back to Top | |||
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Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Fabids | OGEF3668 | 33 | 66 |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT3G48160.2 | 1e-119 | DP-E2F-like 1 |
Publications ? help Back to Top | |||
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