PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

XP_004489178.1

Organism

Cicer arietinum

Taxonomic ID

3827

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Cicereae; Cicer

Family

AP2

Protein Properties

Length: 388aa MW: 45004.2 Da PI: 9.4064

Description

AP2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_004489178.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	49.3	1.2e-15	66	125	1	55
AP2 1 sgykGVrwdkkrgrWvAeIrd.pseng...kr.krfslgkfgtaeeAakaaiaarkkleg 55 s+++GV++++++gr++A+++d s+n k+ k+++lg ++ +e Aa+a++ a+ k++g XP_004489178.1 66 SKFRGVSRHRWTGRYEAHLWDkHSWNItqkKKgKQVYLGAYDEEEAAARAYDLAAIKYWG 125 79*****************999955655447***********************98 PP
2	AP2	52.4	1.3e-16	168	219	1	55
AP2 1 sgykGVrwdkkrgrWvAeIrd.psengkrkrfslgkfgtaeeAakaaiaarkkleg 55 s+y+GV +++ +grW+A+I + g +k+ +lg++ t eeAa+a++ a+ +++g XP_004489178.1 168 SKYRGVARHHHNGRWEARIGRvF---G-NKYLYLGTYSTQEEAARAYDIAAIEYRG 219 89**99******99966...3.6***********************97 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF00847	2.0E-12	66	125	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	2.22E-16	66	134	IPR016177	DNA-binding domain
PROSITE profile	PS51032	19.006	67	133	IPR001471	AP2/ERF domain
SMART	SM00380	2.0E-24	67	139	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	8.2E-15	67	133	IPR001471	AP2/ERF domain
PRINTS	PR00367	6.1E-5	68	79	IPR001471	AP2/ERF domain
CDD	cd00018	7.41E-25	168	229	No hit	No description
SuperFamily	SSF54171	8.5E-18	168	228	IPR016177	DNA-binding domain
Pfam	PF00847	4.8E-12	168	219	IPR001471	AP2/ERF domain
SMART	SM00380	1.6E-26	169	233	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	18.887	169	227	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	4.4E-18	169	228	IPR001471	AP2/ERF domain
PRINTS	PR00367	6.1E-5	209	229	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 388 aa Download sequence Send to blast
MAMMLENEMS LKKSQRSMEK FEVKGARSVK RQRREHVIAS KRGHDNHKQQ VGEIENSTIN 60 TIKRSSKFRG VSRHRWTGRY EAHLWDKHSW NITQKKKGKQ VYLGAYDEEE AAARAYDLAA 120 IKYWGTSTFT NFSISDYEKE VEIMNTMTKE EYLATLRRKS SGFSRGVSKY RGVARHHHNG 180 RWEARIGRVF GNKYLYLGTY STQEEAARAY DIAAIEYRGI HAVTNFELSS YIKWLKPEST 240 TETKHESKAL PQDSQKVASP NNSTLIQESK LLALKKSFFN SDYMNSNEKQ EPSIENKNYS 300 FLSNKSTSPT ALSLLLRSSL FRELLEKNSN VSEDHEVTKE QQQQHNTASD DEFGGIFYDG 360 FDNIQFDFDT NKCNIELQER DLYSIFCT

Sequence ? help Back to Top

Protein Sequence Length: 388 aa Download sequence Send to blast

MAMMLENEMS LKKSQRSMEK FEVKGARSVK RQRREHVIAS KRGHDNHKQQ VGEIENSTIN  60
TIKRSSKFRG VSRHRWTGRY EAHLWDKHSW NITQKKKGKQ VYLGAYDEEE AAARAYDLAA  120
IKYWGTSTFT NFSISDYEKE VEIMNTMTKE EYLATLRRKS SGFSRGVSKY RGVARHHHNG  180
RWEARIGRVF GNKYLYLGTY STQEEAARAY DIAAIEYRGI HAVTNFELSS YIKWLKPEST  240
TETKHESKAL PQDSQKVASP NNSTLIQESK LLALKKSFFN SDYMNSNEKQ EPSIENKNYS  300
FLSNKSTSPT ALSLLLRSSL FRELLEKNSN VSEDHEVTKE QQQQHNTASD DEFGGIFYDG  360
FDNIQFDFDT NKCNIELQER DLYSIFCT

Functional Description ? help Back to Top
Source	Description
UniProt	May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). Transcriptional activator involved in the activation of a subset of sugar-responsive genes and the control of carbon flow from sucrose import to oil accumulation in developing seeds. Binds to the GCC-box pathogenesis-related promoter element. Promotes sugar uptake and seed oil accumulation by glycolysis. Required for embryo development, seed germination and, indirectly, for seedling establishment. Negative regulator of the ABA-mediated germination inhibition. {ECO:0000250, ECO:0000269\|PubMed:12084821, ECO:0000269\|PubMed:15500472, ECO:0000269\|PubMed:15753106, ECO:0000269\|PubMed:16553903, ECO:0000269\|PubMed:16632590, ECO:0000269\|PubMed:9733529}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	XP_004489178.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Transiantly in leaves by sucrose, but not by abscisic acid (ABA). {ECO:0000269\|PubMed:15753106}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AC137994	1e-165	AC137994.19 Medicago truncatula clone mth2-23f15, complete sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_004489178.1	0.0	AP2-like ethylene-responsive transcription factor At1g16060
Swissprot	Q6X5Y6	1e-88	WRI1_ARATH; Ethylene-responsive transcription factor WRI1
TrEMBL	A0A1S2XGW2	0.0	A0A1S2XGW2_CICAR; AP2-like ethylene-responsive transcription factor At1g16060
STRING	XP_004489178.1	0.0	(Cicer arietinum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF2198	32	83

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G79700.2	2e-79	AP2 family protein

Publications ? help Back to Top
Kim HU, et al. Ectopic overexpression of castor bean LEAFY COTYLEDON2 (LEC2) in Arabidopsis triggers the expression of genes that encode regulators of seed maturation and oil body proteins in vegetative tissues. FEBS Open Bio, 2013. 4: p. 25-32 [PMID:24363987] Wu XL,Liu ZH,Hu ZH,Huang RZ BnWRI1 coordinates fatty acid biosynthesis and photosynthesis pathways during oil accumulation in rapeseed. J Integr Plant Biol, 2014. 56(6): p. 582-93 [PMID:24393360] Shigematsu H, et al. Structural characterization of the mechanosensitive channel candidate MCA2 from Arabidopsis thaliana. PLoS ONE, 2014. 9(1): p. e87724 [PMID:24475319] Kim HU, et al. Senescence-inducible LEC2 enhances triacylglycerol accumulation in leaves without negatively affecting plant growth. Plant Biotechnol. J., 2015. 13(9): p. 1346-59 [PMID:25790072] Grimberg Å,Carlsson AS,Marttila S,Bhalerao R,Hofvander P Transcriptional transitions in Nicotiana benthamiana leaves upon induction of oil synthesis by WRINKLED1 homologs from diverse species and tissues. BMC Plant Biol., 2015. 15: p. 192 [PMID:26253704] Kanai M,Mano S,Kondo M,Hayashi M,Nishimura M Extension of oil biosynthesis during the mid-phase of seed development enhances oil content in Arabidopsis seeds. Plant Biotechnol. J., 2016. 14(5): p. 1241-50 [PMID:26503031] Li Q, et al. Wrinkled1 Accelerates Flowering and Regulates Lipid Homeostasis between Oil Accumulation and Membrane Lipid Anabolism in Brassica napus. Front Plant Sci, 2015. 6: p. 1015 [PMID:26635841] Hofvander P, et al. Potato tuber expression of Arabidopsis WRINKLED1 increase triacylglycerol and membrane lipids while affecting central carbohydrate metabolism. Plant Biotechnol. J., 2016. 14(9): p. 1883-98 [PMID:26914183] Shen SL, et al. CitAP2.10 activation of the terpene synthase CsTPS1 is associated with the synthesis of (+)-valencene in 'Newhall' orange. J. Exp. Bot., 2016. 67(14): p. 4105-15 [PMID:27194737] Adhikari ND,Bates PD,Browse J WRINKLED1 Rescues Feedback Inhibition of Fatty Acid Synthesis in Hydroxylase-Expressing Seeds. Plant Physiol., 2016. 171(1): p. 179-91 [PMID:27208047] Kim MJ,Jang IC,Chua NH The Mediator Complex MED15 Subunit Mediates Activation of Downstream Lipid-Related Genes by the WRINKLED1 Transcription Factor. Plant Physiol., 2016. 171(3): p. 1951-64 [PMID:27246098] Bhattacharya S,Das N,Maiti MK Cumulative effect of heterologous AtWRI1 gene expression and endogenous BjAGPase gene silencing increases seed lipid content in Indian mustard Brassica juncea. Plant Physiol. Biochem., 2016. 107: p. 204-213 [PMID:27314514] Ma W, et al. 14-3-3 protein mediates plant seed oil biosynthesis through interaction with AtWRI1. Plant J., 2016. 88(2): p. 228-235 [PMID:27322486] Li D, et al. MYB89 Transcription Factor Represses Seed Oil Accumulation. Plant Physiol., 2017. 173(2): p. 1211-1225 [PMID:27932421] Ivarson E, et al. Effects of Overexpression of WRI1 and Hemoglobin Genes on the Seed Oil Content of Lepidium campestre. Front Plant Sci, 2016. 7: p. 2032 [PMID:28119714] An D, et al. Expression of Camelina WRINKLED1 Isoforms Rescue the Seed Phenotype of the Arabidopsis wri1 Mutant and Increase the Triacylglycerol Content in Tobacco Leaves. Front Plant Sci, 2017. 8: p. 34 [PMID:28174580] Zhai Z,Liu H,Shanklin J Phosphorylation of WRINKLED1 by KIN10 Results in Its Proteasomal Degradation, Providing a Link between Energy Homeostasis and Lipid Biosynthesis. Plant Cell, 2017. 29(4): p. 871-889 [PMID:28314829] Jin J, et al. Transcriptome and functional analysis reveals hybrid vigor for oil biosynthesis in oil palm. Sci Rep, 2017. 7(1): p. 439 [PMID:28348403] Kong Q, et al. The Arabidopsis WRINKLED1 transcription factor affects auxin homeostasis in roots. J. Exp. Bot., 2017. 68(16): p. 4627-4634 [PMID:28981783] Kang NK, et al. Increased lipid production by heterologous expression of AtWRI1 transcription factor in Nannochloropsis salina. Biotechnol Biofuels, 2017. 10: p. 231 [PMID:29046718] Pellaud S, et al. WRINKLED1 and ACYL-COA:DIACYLGLYCEROL ACYLTRANSFERASE1 regulate tocochromanol metabolism in Arabidopsis. New Phytol., 2018. 217(1): p. 245-260 [PMID:29105089] Hanano A,Almousally I,Shaban M,Murphy DJ Arabidopsis plants exposed to dioxin result in a WRINKLED seed phenotype due to 20S proteasomal degradation of WRI1. J. Exp. Bot., 2018. 69(7): p. 1781-1794 [PMID:29394403]