PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID CA11g05160
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Capsiceae; Capsicum
Family MYB
Protein Properties Length: 474aa    MW: 52903.1 Da    PI: 6.5136
Description MYB family protein
Gene Model
Gene Model ID Type Source Coding Sequence
CA11g05160genomePEPView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding44.63.4e-141761348
                     SS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS
  Myb_DNA-binding  3 rWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48
                     +W++eEd++l + ++ +G+++W+ Ia+++   +t  qc+ rw++yl
       CA11g05160 17 SWSQEEDDILREQIRIHGTDNWTIIASKFK-DKTTRQCRRRWFTYL 61
                     6****************************9.*************97 PP

2Myb_DNA-binding44.14.7e-1467110146
                      TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHH CS
  Myb_DNA-binding   1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqk 46 
                      +g W++eEd ll +a k +G++ W+ Ia+ +  gRt++ +k+r+ +
       CA11g05160  67 KGGWSPEEDILLCEAQKIFGNR-WTEIAKVVS-GRTDNAVKNRFTT 110
                      688*******************.*********.**********976 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5129416.1931061IPR017930Myb domain
Gene3DG3DSA:1.10.10.601.0E-161062IPR009057Homeodomain-like
SMARTSM007174.7E-131463IPR001005SANT/Myb domain
SuperFamilySSF466895.24E-2615108IPR009057Homeodomain-like
CDDcd001671.12E-121761No hitNo description
PfamPF139213.8E-151878No hitNo description
PROSITE profilePS5129420.62462116IPR017930Myb domain
Gene3DG3DSA:1.10.10.608.5E-2063115IPR009057Homeodomain-like
SMARTSM007177.3E-1566114IPR001005SANT/Myb domain
CDDcd001677.03E-1170111No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009553Biological Processembryo sac development
GO:0010052Biological Processguard cell differentiation
GO:0005634Cellular Componentnucleus
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 474 aa     Download sequence    Send to blast
MKRSVEAAKT KERHIVSWSQ EEDDILREQI RIHGTDNWTI IASKFKDKTT RQCRRRWFTY  60
LNSDFKKGGW SPEEDILLCE AQKIFGNRWT EIAKVVSGRT DNAVKNRFTT LCKKRAKHEA  120
LAKENSNSYI NLNNKRVIFP SGLNMDNITE ATAPIKKLRR SDISDVLPIG NEGEKSMGDC  180
GTTNPLLRHP FAVLAQNLHN AGENLASHQR TTGSAGSDNK TQGTFLKKDD PKVHVLMQQA  240
ELLSSLAMKV NTENTDQSLE NAWKILQDFL QQTKDGDMLK FQLPEMNFEP GDYKNLIADS  300
RSSNEGTQPS WRQPALSEDS AGSSEYSTGS TLLSHALADK TEESQAEVCA HHQDIESELR  360
TSQMSDQAGL HELENGISCR VSTTRDTLPV CDEEKVNNGP ATAECEFLNT DFSSPHQVTP  420
LFRSLAAEIP TPKFSESERQ FLLKTLGVES TSLHPGTNLS QPPSCKRALL HSL*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1a5j_A1e-261811610108B-MYB
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that binds to DNA in promoters cis-regulatory element 5'-GGCGCGC-3' of cell cycle genes, including cyclins, cyclin-dependent kinases (CDKs), and components of the pre-replication complex (PubMed:20675570, PubMed:24687979). Binds to DNA in promoters cis-regulatory element 5'-AGCCG-3' of auxin regulated genes (e.g. PIN3 and PIN7) (PubMed:26578169). Together with FAMA and MYB88, ensures that stomata contain just two guard cells (GCs) by enforcing a single symmetric precursor cell division before stomatal maturity (PubMed:24571519). Represses the expression of the mitosis-inducing factors CDKB1-1 and CDKA-1, specifically required for the last guard mother cells (GMC) symmetric divisions in the stomatal pathway (PubMed:20675570, PubMed:24687979). Represses CYCA2-3 in newly formed guard cells (PubMed:21772250). Together with MYB88, regulates stomata spacing by restricting divisions late in the stomatal cell lineage thus limiting the number of GMC divisions (PubMed:11536724, PubMed:9684356, PubMed:16155180, PubMed:24123248). In collaboration with CDKB1-1 and CDKB1-2, restrict the G1/S transition and chloroplast and nuclear number during stomatal formation, and normally maintain fate and developmental progression throughout the stomatal cell lineage (PubMed:24123248). Also involved in the shape regulation of pavement cells (PubMed:9684356). Involved in sensing and/or transducing abiotic stress (e.g. drought and salt), probably via the positive regulation of NAC019 (PubMed:21105921). Regulates female reproduction being required for entry into megasporogenesis, probably via the regulation of cell cycle genes (PubMed:22915737). Promotes histone H3K27me3 marks and represses stem cell gene expression (PubMed:24654956). Required for lateral roots (LRs) initiation via the regulation of PIN3 expression in an auxin-dependent manner (PubMed:26578065). Involved in responses to gravity stimulation in primary roots by regulating the transcription of PIN3 and PIN7 in gravity-sensing cells, thus modulating auxin asymmetric redistribution (PubMed:26578169). {ECO:0000269|PubMed:11536724, ECO:0000269|PubMed:16155180, ECO:0000269|PubMed:20675570, ECO:0000269|PubMed:21105921, ECO:0000269|PubMed:21772250, ECO:0000269|PubMed:22915737, ECO:0000269|PubMed:24123248, ECO:0000269|PubMed:24571519, ECO:0000269|PubMed:24654956, ECO:0000269|PubMed:24687979, ECO:0000269|PubMed:26578065, ECO:0000269|PubMed:26578169, ECO:0000269|PubMed:9684356}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Strongly induced by auxin in a IAA14/SLR1 and ARF7 dependent manner, especially in xylem pole pericycle cells, lateral roots initiating cells. {ECO:0000269|PubMed:26578065}.
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAC1451203e-99AC145120.1 Solanum demissum chromosome 5 clone PGEC446O19, complete sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_016547761.10.0PREDICTED: uncharacterized protein LOC107847790 isoform X1
RefseqXP_016547762.10.0PREDICTED: uncharacterized protein LOC107847790 isoform X1
RefseqXP_016547764.10.0PREDICTED: uncharacterized protein LOC107847790 isoform X1
SwissprotQ94FL61e-167MY124_ARATH; Transcription factor MYB124
TrEMBLA0A1U8EV390.0A0A1U8EV39_CAPAN; uncharacterized protein LOC107847790 isoform X1
STRINGSolyc05g007160.2.10.0(Solanum lycopersicum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA41242134
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G14350.21e-170MYB family protein
Publications ? help Back to Top
  1. Yang M,Sack FD
    The too many mouths and four lips mutations affect stomatal production in Arabidopsis.
    Plant Cell, 1995. 7(12): p. 2227-39
    [PMID:11536724]
  2. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  3. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  4. Yang K, et al.
    Requirement for A-type cyclin-dependent kinase and cyclins for the terminal division in the stomatal lineage of Arabidopsis.
    J. Exp. Bot., 2014. 65(9): p. 2449-61
    [PMID:24687979]
  5. Yang M
    The FOUR LIPS (FLP) and MYB88 genes conditionally suppress the production of nonstomatal epidermal cells in Arabidopsis cotyledons.
    Am. J. Bot., 2016. 103(9): p. 1559-66
    [PMID:27620181]
  6. Xie Y, et al.
    An atypical R2R3 MYB transcription factor increases cold hardiness by CBF-dependent and CBF-independent pathways in apple.
    New Phytol., 2018. 218(1): p. 201-218
    [PMID:29266327]