PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

CA07g17430

Organism

Capsicum annuum

Taxonomic ID

4072

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Capsiceae; Capsicum

Family

HD-ZIP

Protein Properties

Length: 448aa MW: 50964 Da PI: 6.3346

Description

HD-ZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
CA07g17430	genome	PEP	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Homeobox	54.7	1.8e-17	17	69	5	57
SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHHC CS Homeobox 5 ttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakekk 57 ++++eq++ Le+ F +++++ e++ +L+k+lg++ rq+++W+qNrRa++k+ CA07g17430 17 KRLNQEQVKLLEASFDSTKKLELEKKLQLSKELGVPPRQISIWYQNRRARWKN 69 5689***********************************************95 PP
2	HD-ZIP_I/II	97.8	1.1e-31	15	106	2	93
HD-ZIP_I/II 2 kkrrlskeqvklLEesFeeeekLeperKvelareLglqprqvavWFqnrRARtktkqlEkdyeaLkraydalkeenerLekeveeLreelke 93 +k+rl++eqvklLE sF++++kLe e+K +l++eLg+ prq+ +W+qnrRAR+k+++lE+dy+aL+ ++++ +e+ +Leke+e Lr el++ CA07g17430 15 NKKRLNQEQVKLLEASFDSTKKLELEKKLQLSKELGVPPRQISIWYQNRRARWKNQNLENDYNALQLKLENALSEKMQLEKETEFLRGELQR 106 69*************************************************************************************99986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50071	15.435	10	70	IPR001356	Homeobox domain
SMART	SM00389	4.8E-14	14	74	IPR001356	Homeobox domain
SuperFamily	SSF46689	5.56E-16	16	78	IPR009057	Homeodomain-like
Pfam	PF00046	8.1E-15	16	69	IPR001356	Homeobox domain
CDD	cd00086	3.04E-13	16	71	No hit	No description
Gene3D	G3DSA:1.10.10.60	1.6E-18	17	77	IPR009057	Homeodomain-like
PROSITE pattern	PS00027	0	45	68	IPR017970	Homeobox, conserved site
Pfam	PF11789	4.9E-13	341	403	IPR004181	Zinc finger, MIZ-type
Gene3D	G3DSA:3.30.40.10	2.4E-6	356	402	IPR013083	Zinc finger, RING/FYVE/PHD-type
SuperFamily	SSF57850	1.41E-6	356	404	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0006974	Biological Process	cellular response to DNA damage stimulus
GO:0008284	Biological Process	positive regulation of cell proliferation
GO:0010082	Biological Process	regulation of root meristem growth
GO:0016925	Biological Process	protein sumoylation
GO:0032876	Biological Process	negative regulation of DNA endoreduplication
GO:0045931	Biological Process	positive regulation of mitotic cell cycle
GO:0060250	Biological Process	germ-line stem-cell niche homeostasis
GO:0080038	Biological Process	positive regulation of cytokinin-activated signaling pathway
GO:0005634	Cellular Component	nucleus
GO:0008270	Molecular Function	zinc ion binding
GO:0019789	Molecular Function	SUMO transferase activity
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 448 aa Download sequence Send to blast
MNSSFNSQNL QKYPNKKRLN QEQVKLLEAS FDSTKKLELE KKLQLSKELG VPPRQISIWY 60 QNRRARWKNQ NLENDYNALQ LKLENALSEK MQLEKETEFL RGELQRANEM LIAINSGAQG 120 QIREFSLSSS CCDQDVVSYT STTWVHTDHE VNYNLQFDEL YAMIGVEEGS NKCYSTCKLK 180 LNNLRPNDAV KPSKWRRRPX XXGSGGVATG RIRSTTSALY SDSQSLLREI RKSIAMMKDI 240 AVELERDERK EMVKELEDGV VQLLAASDDC MHLSEAIQSI GDEIEPGPEP TNFKKKFDEE 300 IAKSKARSSS HAQNQSLLRQ FREAIWHVHH AGQPLPGDEQ EDIVMTSTQC NLLNVTCPLS 360 GKPVTELAEP VRSMDCKHIY EKKTIMQYLK SKTSRGQCPV AGCPKILKAQ RVLCDPFLLI 420 EIDELMSTSK QNRPDAIEDF TVLDDED*

Sequence ? help Back to Top

Protein Sequence Length: 448 aa Download sequence Send to blast

MNSSFNSQNL QKYPNKKRLN QEQVKLLEAS FDSTKKLELE KKLQLSKELG VPPRQISIWY  60
QNRRARWKNQ NLENDYNALQ LKLENALSEK MQLEKETEFL RGELQRANEM LIAINSGAQG  120
QIREFSLSSS CCDQDVVSYT STTWVHTDHE VNYNLQFDEL YAMIGVEEGS NKCYSTCKLK  180
LNNLRPNDAV KPSKWRRRPX XXGSGGVATG RIRSTTSALY SDSQSLLREI RKSIAMMKDI  240
AVELERDERK EMVKELEDGV VQLLAASDDC MHLSEAIQSI GDEIEPGPEP TNFKKKFDEE  300
IAKSKARSSS HAQNQSLLRQ FREAIWHVHH AGQPLPGDEQ EDIVMTSTQC NLLNVTCPLS  360
GKPVTELAEP VRSMDCKHIY EKKTIMQYLK SKTSRGQCPV AGCPKILKAQ RVLCDPFLLI  420
EIDELMSTSK QNRPDAIEDF TVLDDED*

Functional Description ? help Back to Top
Source	Description
UniProt	E3 SUMO-protein ligase that modulates cell cycle progression and functions as a repressor of endocycle onset in meristems. May function downstream of the meristem patterning transcription factors PLETHORA 1 and 2 (PLT1 and PLT2) in root meristem development. Modulates the expression of the mitotic cyclins CYCB1-1 and CYCB1-2 and cyclin-dependent kinases CDKB1-1 and CDKB2-1 in root meristem. Involved in cytokinin signaling in root development. {ECO:0000269\|PubMed:19666737, ECO:0000269\|PubMed:19682286}.

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	HG975446	1e-130	HG975446.1 Solanum pennellii chromosome ch07, complete genome.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_016579531.1	1e-180	PREDICTED: E3 SUMO-protein ligase MMS21
Swissprot	Q8GYH7	4e-89	NSE2_ARATH; E3 SUMO-protein ligase MMS21
TrEMBL	A0A1U8H7Q8	1e-179	A0A1U8H7Q8_CAPAN; E3 SUMO-protein ligase MMS21
STRING	PGSC0003DMT400032388	1e-156	(Solanum tuberosum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA10743	2	2

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G53980.1	5e-20	homeobox protein 52

Publications ? help Back to Top
Lee J, et al. Salicylic acid-mediated innate immunity in Arabidopsis is regulated by SIZ1 SUMO E3 ligase. Plant J., 2007. 49(1): p. 79-90 [PMID:17163880] Huang L, et al. The Arabidopsis SUMO E3 ligase AtMMS21, a homologue of NSE2/MMS21, regulates cell proliferation in the root. Plant J., 2009. 60(4): p. 666-78 [PMID:19682286] Zhang S,Qi Y,Yang C Arabidopsis SUMO E3 ligase AtMMS21 regulates root meristem development. Plant Signal Behav, 2010. 5(1): p. 53-5 [PMID:20592809] Ishida T,Yoshimura M,Miura K,Sugimoto K MMS21/HPY2 and SIZ1, two Arabidopsis SUMO E3 ligases, have distinct functions in development. PLoS ONE, 2012. 7(10): p. e46897 [PMID:23056518] Zhang S,Qi Y,Liu M,Yang C SUMO E3 ligase AtMMS21 regulates drought tolerance in Arabidopsis thaliana(F). J Integr Plant Biol, 2013. 55(1): p. 83-95 [PMID:23231763] Xu P, et al. AtMMS21, an SMC5/6 complex subunit, is involved in stem cell niche maintenance and DNA damage responses in Arabidopsis roots. Plant Physiol., 2013. 161(4): p. 1755-68 [PMID:23426194] Okushima Y,Shimizu K,Ishida T,Sugimoto K,Umeda M Differential regulation of B2-type CDK accumulation in Arabidopsis roots. Plant Cell Rep., 2014. 33(7): p. 1033-40 [PMID:24573537] Yuan D, et al. AtMMS21 regulates DNA damage response and homologous recombination repair in Arabidopsis. DNA Repair (Amst.), 2014. 21: p. 140-7 [PMID:24795278] Liu M, et al. SUMO E3 ligase AtMMS21 is required for normal meiosis and gametophyte development in Arabidopsis. BMC Plant Biol., 2014. 14: p. 153 [PMID:24893774] Kwak JS,Son GH,Kim SI,Song JT,Seo HS Arabidopsis HIGH PLOIDY2 Sumoylates and Stabilizes Flowering Locus C through Its E3 Ligase Activity. Front Plant Sci, 2016. 7: p. 530 [PMID:27148346] Liu Y, et al. The Arabidopsis SUMO E3 Ligase AtMMS21 Dissociates the E2Fa/DPa Complex in Cell Cycle Regulation. Plant Cell, 2016. 28(9): p. 2225-2237 [PMID:27492969] Liu L, et al. Transcriptional Gene Silencing Maintained by OTS1 SUMO Protease Requires a DNA-Dependent Polymerase V-Dependent Pathway. Plant Physiol., 2017. 173(1): p. 655-667 [PMID:27852949] Zhang J, et al. A SUMO Ligase AtMMS21 Regulates the Stability of the Chromatin Remodeler BRAHMA in Root Development. Plant Physiol., 2017. 173(3): p. 1574-1582 [PMID:28115583] Yu M, et al. A SUMO ligase AtMMS21 regulates activity of the 26S proteasome in root development. Plant Sci., 2019. 280: p. 314-320 [PMID:30824010]