PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID CA04g04240
Organism
Capsicum annuum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Capsiceae; Capsicum
Family ARF
Protein Properties Length: 806aa    MW: 90307.6 Da    PI: 6.5117
Description ARF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
CA04g04240genomePEPView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B360.52.9e-1977187199
                 EEEE-..-HHHHTT-EE--HHH.HTT......---..--SEEEEEETTS-EEEEEE...........EEETTEEEE-TTHHHHHHHHT--TT-EEEEEE CS
          B3   1 ffkvltpsdvlksgrlvlpkkfaeeh......ggkkeesktltledesgrsWevkliy.........rkksgryvltkGWkeFvkangLkegDfvvFkl 84 
                 f+k+lt sd++++g +++p++ ae+       ++ +++ ++l+ +d++  +W++++i+           +++r++lt+GW+ Fv+a++L +gD+v+F  
  CA04g04240  77 FCKTLTASDTSTHGGFSVPRRAAEKVfppldfSQTPPC-QELIARDLHDIEWKFRHIFrgklwrllsMLCPKRHLLTTGWSVFVSAKRLVAGDSVLFI- 173
                 99*****************************7555555.59***************99777755555445666*************************. PP

                 -SSSEE..EEEEE-S CS
          B3  85 dgrsefelvvkvfrk 99 
                  ++++ +l+++++r+
  CA04g04240 174 -WNEKNQLLLGIRRA 187
                 .8899999****997 PP
2Auxin_resp109.43.7e-36212296183
  Auxin_resp   1 aahaastksvFevvYnPr.astseFvvkvekvekalk.vkvsvGmRfkmafetedsserrlsGtvvgvsdldpvrWpnSkWrsLk 83 
                 aahaa+t+s F+v++nPr as+seFv++++k+ ka++ ++vsvGmRf+m fete+ss rr++Gt++g+ dldpvrW nS+Wrs+k
  CA04g04240 212 AAHAAATNSCFTVFFNPRwASPSEFVIPLSKYIKAVYhTRVSVGMRFRMLFETEESSVRRYMGTITGIGDLDPVRWANSHWRSVK 296
                 79***************85899**************9789******************************************985 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019363.4E-4661215IPR015300DNA-binding pseudobarrel domain
Gene3DG3DSA:2.40.330.102.1E-3770201IPR015300DNA-binding pseudobarrel domain
CDDcd100173.38E-1976186No hitNo description
PfamPF023622.2E-1777187IPR003340B3 DNA binding domain
PROSITE profilePS5086311.09677188IPR003340B3 DNA binding domain
SMARTSM010193.2E-1677188IPR003340B3 DNA binding domain
PfamPF065071.9E-31212296IPR010525Auxin response factor
PfamPF023093.3E-8671764IPR033389AUX/IAA domain
SuperFamilySSF542775.89E-7677752No hitNo description
PROSITE profilePS5174524.455678762IPR000270PB1 domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009733Biological Processresponse to auxin
GO:0009908Biological Processflower development
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0005515Molecular Functionprotein binding
Sequence ? help Back to Top
Protein Sequence    Length: 806 aa     Download sequence    Send to blast
MKVAATTNKE VDAHIPNYPN LPPQLICQLH NVTMHADVET DEVYAQMTLQ PLTPQEQKDT  60
YLPVELGIPS RQPTNYFCKT LTASDTSTHG GFSVPRRAAE KVFPPLDFSQ TPPCQELIAR  120
DLHDIEWKFR HIFRGKLWRL LSMLCPKRHL LTTGWSVFVS AKRLVAGDSV LFIWNEKNQL  180
LLGIRRATRP QTVMPSSVIS SDSMHIGLLA AAAHAAATNS CFTVFFNPRW ASPSEFVIPL  240
SKYIKAVYHT RVSVGMRFRM LFETEESSVR RYMGTITGIG DLDPVRWANS HWRSVKVGWD  300
ESTAGERQPR VSLWEIEPLT TFPMYPSLFP LRLKRPWYPG SSSFQDNSSE ALNGMAWLRG  360
ESGEQGPHLM NLQSFGGMLP WMQQRVDPTI LRNDLNQQYQ AMLASGLQNF GSGDLMKQQL  420
MQFQQPVQYV QHAGSHNPLL QQQQQQQQQA MQQAIHQHML PAQPQIDNLQ RQQQQHVSNQ  480
TEEQSHQHSY QEAYQIPNSQ LQQKQPSNVP SPSFSKPDIA DQSPKFSASV SPSGMPSALG  540
SLCSEGTSNF LNFNIIGQQP VIMEQPPQKS WMQKFSHTQL NTGSNSSSLS GYAKDTSNSQ  600
ETCSLDAQNQ TLFGANVDSS GLLLPTTVSN VATTSIDADM STIPLGTSGF QNSLYGYVQD  660
SSDLLHNVGQ VDAQTATRTF VKVYKSGSVG RSLDITRFNS YHELRQELGQ MFGIEGFLEN  720
PQRSGWQLVF VDRENDVLLL GDDPWEAFVN NVWYIKILSP EDVQKLGKEE VESLNRGALE  780
RMSNNNSADG RDFISGLPSI GSLEY*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4ldu_A1e-130231783388Auxin response factor 5
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtAuxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Seems to act as transcriptional activator. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. Regulates both stamen and gynoecium maturation. Promotes jasmonic acid production. Partially redundant with ARF6. Involved in fruit initiation. Acts as an inhibitor to stop further carpel development in the absence of fertilization and the generation of signals required to initiate fruit and seed development. {ECO:0000269|PubMed:12036261, ECO:0000269|PubMed:16107481, ECO:0000269|PubMed:16829592}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00033PBMTransfer from AT5G37020Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Repressed by miR167. {ECO:0000269|PubMed:17021043}.
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankHM5609790.0HM560979.1 Solanum lycopersicum auxin response factor 8-1 (ARF8-1) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_016570411.10.0PREDICTED: auxin response factor 8-like
SwissprotQ9FGV10.0ARFH_ARATH; Auxin response factor 8
TrEMBLA0A1U8GGH70.0A0A1U8GGH7_CAPAN; Auxin response factor
STRINGSolyc03g031970.2.10.0(Solanum lycopersicum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA38572339
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G37020.10.0auxin response factor 8
Publications ? help Back to Top
  1. Liu N, et al.
    Down-regulation of AUXIN RESPONSE FACTORS 6 and 8 by microRNA 167 leads to floral development defects and female sterility in tomato.
    J. Exp. Bot., 2014. 65(9): p. 2507-20
    [PMID:24723401]
  2. Minato N, et al.
    The phytoplasmal virulence factor TENGU causes plant sterility by downregulating of the jasmonic acid and auxin pathways.
    Sci Rep, 2014. 4: p. 7399
    [PMID:25492247]
  3. Ortega-Amaro MA, et al.
    Overexpression of AtGRDP2, a novel glycine-rich domain protein, accelerates plant growth and improves stress tolerance.
    Front Plant Sci, 2014. 5: p. 782
    [PMID:25653657]
  4. Wang Y, et al.
    MicroRNA167-Directed Regulation of the Auxin Response Factors GmARF8a and GmARF8b Is Required for Soybean Nodulation and Lateral Root Development.
    Plant Physiol., 2015. 168(3): p. 984-99
    [PMID:25941314]
  5. Barik S, et al.
    Coevolution Pattern and Functional Conservation or Divergence of miR167s and their targets across Diverse Plant Species.
    Sci Rep, 2015. 5: p. 14611
    [PMID:26459056]
  6. Pashkovskiy PP,Kartashov AV,Zlobin IE,Pogosyan SI,Kuznetsov VV
    Blue light alters miR167 expression and microRNA-targeted auxin response factor genes in Arabidopsis thaliana plants.
    Plant Physiol. Biochem., 2016. 104: p. 146-54
    [PMID:27031426]
  7. Mlotshwa S,Pruss GJ,MacArthur JL,Reed JW,Vance V
    Developmental Defects Mediated by the P1/HC-Pro Potyviral Silencing Suppressor Are Not Due to Misregulation of AUXIN RESPONSE FACTOR 8.
    Plant Physiol., 2016. 172(3): p. 1853-1861
    [PMID:27688620]
  8. Wójcikowska B,Gaj MD
    Expression profiling of AUXIN RESPONSE FACTOR genes during somatic embryogenesis induction in Arabidopsis.
    Plant Cell Rep., 2017. 36(6): p. 843-858
    [PMID:28255787]
  9. Zhang GZ, et al.
    Ectopic expression of UGT84A2 delayed flowering by indole-3-butyric acid-mediated transcriptional repression of ARF6 and ARF8 genes in Arabidopsis.
    Plant Cell Rep., 2017. 36(12): p. 1995-2006
    [PMID:29027578]
  10. Zheng K, et al.
    Involvement of PACLOBUTRAZOL RESISTANCE6/KIDARI, an Atypical bHLH Transcription Factor, in Auxin Responses in Arabidopsis.
    Front Plant Sci, 2017. 8: p. 1813
    [PMID:29114256]
  11. Liu Z, et al.
    ARF2-ARF4 and ARF5 are Essential for Female and Male Gametophyte Development in Arabidopsis.
    Plant Cell Physiol., 2018. 59(1): p. 179-189
    [PMID:29145642]
  12. Ghelli R, et al.
    A Newly Identified Flower-Specific Splice Variant of AUXIN RESPONSE FACTOR8 Regulates Stamen Elongation and Endothecium Lignification in Arabidopsis.
    Plant Cell, 2018. 30(3): p. 620-637
    [PMID:29514943]