PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

CA02g30090

Organism

Capsicum annuum

Taxonomic ID

4072

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Capsiceae; Capsicum

Family

NAC

Protein Properties

Length: 388aa MW: 43104 Da PI: 4.8098

Description

NAC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
CA02g30090	genome	PEP	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NAM	103.6	2.6e-32	55	197	1	128
NAM 1 lppGfrFhPtdeelvveyLkkkvegkk...lelee....vikevd....iykvePwdLpkkvkaeekewyfFskrdkkyatgkrknra........tks 80 lp+G++F+P+d elv e+L++k+ ++ + + +i+++d i++++P++Lp +k++ ++++fF + ++yatgkrk+r+ ++ CA02g30090 55 LPVGVKFDPSDAELV-EHLQAKCGMENseqH---KfideFIPTLDvyegICYTHPEKLP-GAKKDGSSIHFFYRITNAYATGKRKRRKihdennlmNEH 148 799**********.99988884442...322224666655555999***.556778899**************867777776669 PP NAM 81 gyWkatgkdkevlskkgelvglkktLvfy..kgrapkgektdWvmheyrl 128 +W++tgk+k +++ +g ++g+kk++v+y +++ +k ekt+Wvmh+y+l CA02g30090 149 VRWHKTGKTKIIVE-NGLQKGCKKVMVLYqtTKKGSKQEKTNWVMHQYHL 197 99**999999.999*******5435677888*******98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF101941	5.36E-37	40	216	IPR003441	NAC domain
PROSITE profile	PS51005	30.003	55	216	IPR003441	NAC domain
Pfam	PF02365	2.5E-14	56	197	IPR003441	NAC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 388 aa Download sequence Send to blast
MGRSWLIDGR GLASKVKNAG APAALQIKDC GAKRQCPNCH YCIDNNDVSP EWPGLPVGVK 60 FDPSDAELVE HLQAKCGMEN SEQHKFIDEF IPTLDVYEGI CYTHPEKLPG AKKDGSSIHF 120 FYRITNAYAT GKRKRRKIHD ENNLMNEHVR WHKTGKTKII VENGLQKGCK KVMVLYQTTK 180 KGSKQEKTNW VMHQYHLGTD EEEKEGEYVV SKIFYQQQKQ SVKANDSLDN EEASVGANQT 240 GPTTPKTVIP DPPRAGETPS CDDIVDDPFP SSPYQEVEVA NEPGQTSDAK IKCEMEYSTC 300 LAGESQAADD VDISLLCDEP NNYSFLDSLG PSSDYTHNPC HLPQGNGSTT CGIPELDNLE 360 LDTPPDFQLS DLPFGSQENI FSWLDRL*

Sequence ? help Back to Top

Protein Sequence Length: 388 aa Download sequence Send to blast

MGRSWLIDGR GLASKVKNAG APAALQIKDC GAKRQCPNCH YCIDNNDVSP EWPGLPVGVK  60
FDPSDAELVE HLQAKCGMEN SEQHKFIDEF IPTLDVYEGI CYTHPEKLPG AKKDGSSIHF  120
FYRITNAYAT GKRKRRKIHD ENNLMNEHVR WHKTGKTKII VENGLQKGCK KVMVLYQTTK  180
KGSKQEKTNW VMHQYHLGTD EEEKEGEYVV SKIFYQQQKQ SVKANDSLDN EEASVGANQT  240
GPTTPKTVIP DPPRAGETPS CDDIVDDPFP SSPYQEVEVA NEPGQTSDAK IKCEMEYSTC  300
LAGESQAADD VDISLLCDEP NNYSFLDSLG PSSDYTHNPC HLPQGNGSTT CGIPELDNLE  360
LDTPPDFQLS DLPFGSQENI FSWLDRL*

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	131	136	KRKRRK

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor regulating the transcriptional activation response to gamma irradiation (PubMed:19549833). Required for stem-cell death induced by UVB or by gamma irradiation (PubMed:20634150). Not required for ATM activation, but participates in pathways governed by both ATM and ATR sensor kinases (PubMed:19549833). Involved in DNA damage response (DDR) system that regulates cell cycle arrest (PubMed:24399300). Functional homolog of animal p53 (PubMed:24736489). Regulates SMR5 and SMR7 transcription (PubMed:24399300). Regulates DNA repair and cytokinin signaling separately and plays a key role in controlling lateral root formation under genotoxic stress. {ECO:0000269\|PubMed:19549833, ECO:0000269\|PubMed:20634150, ECO:0000269\|PubMed:24399300, ECO:0000305\|PubMed:24736489}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Not induced by zeocin or ionizing radiation treatment. {ECO:0000269\|PubMed:23907539}.

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AC215373	0.0	AC215373.2 Solanum lycopersicum cultivar Heinz 1706 chromosome 2 clone C02HBa0064B17, complete sequence.
GenBank	AC215453	0.0	AC215453.2 Solanum lycopersicum cultivar Heinz 1706 chromosome 2 clone C02SLe0034H10, complete sequence.
GenBank	HG975514	0.0	HG975514.1 Solanum lycopersicum chromosome ch02, complete genome.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_016561625.1	0.0	PREDICTED: NAC domain-containing protein 8 isoform X2
Swissprot	Q6NQK2	5e-87	NAC8_ARATH; SUPPRESSOR OF GAMMA RESPONSE 1
TrEMBL	A0A1U8FS79	0.0	A0A1U8FS79_CAPAN; NAC domain-containing protein 8 isoform X2
STRING	PGSC0003DMT400032829	0.0	(Solanum tuberosum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA8175	22	29

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G01600.1	3e-94	NAC domain containing protein 44

Publications ? help Back to Top
Yi D, et al. The Arabidopsis SIAMESE-RELATED cyclin-dependent kinase inhibitors SMR5 and SMR7 regulate the DNA damage checkpoint in response to reactive oxygen species. Plant Cell, 2014. 26(1): p. 296-309 [PMID:24399300] Biever JJ,Brinkman D,Gardner G UV-B inhibition of hypocotyl growth in etiolated Arabidopsis thaliana seedlings is a consequence of cell cycle arrest initiated by photodimer accumulation. J. Exp. Bot., 2014. 65(11): p. 2949-61 [PMID:24591052] Hu Z,Cools T,Kalhorzadeh P,Heyman J,De Veylder L Deficiency of the Arabidopsis helicase RTEL1 triggers a SOG1-dependent replication checkpoint in response to DNA cross-links. Plant Cell, 2015. 27(1): p. 149-61 [PMID:25595823] Chen P,Umeda M DNA double-strand breaks induce the expression of flavin-containing monooxygenase and reduce root meristem size in Arabidopsis thaliana. Genes Cells, 2015. 20(8): p. 636-46 [PMID:26033196] Sjogren CA,Bolaris SC,Larsen PB Aluminum-Dependent Terminal Differentiation of the Arabidopsis Root Tip Is Mediated through an ATR-, ALT2-, and SOG1-Regulated Transcriptional Response. Plant Cell, 2015. 27(9): p. 2501-15 [PMID:26320227] Yoshiyama KO SOG1: a master regulator of the DNA damage response in plants. Genes Genet. Syst., 2016. 90(4): p. 209-16 [PMID:26617076] Weimer AK, et al. The plant-specific CDKB1-CYCB1 complex mediates homologous recombination repair in Arabidopsis. EMBO J., 2016. 35(19): p. 2068-2086 [PMID:27497297] Davis OM,Ogita N,Inagaki S,Takahashi N,Umeda M DNA damage inhibits lateral root formation by up-regulating cytokinin biosynthesis genes in Arabidopsis thaliana. Genes Cells, 2016. 21(11): p. 1195-1208 [PMID:27658920] Pedroza-García JA, et al. Function of the Plant DNA Polymerase Epsilon in Replicative Stress Sensing, a Genetic Analysis. Plant Physiol., 2017. 173(3): p. 1735-1749 [PMID:28153919] Horvath BM, et al. Arabidopsis RETINOBLASTOMA RELATED directly regulates DNA damage responses through functions beyond cell cycle control. EMBO J., 2017. 36(9): p. 1261-1278 [PMID:28320736] Sjogren CA,Larsen PB SUV2, which encodes an ATR-related cell cycle checkpoint and putative plant ATRIP, is required for aluminium-dependent root growth inhibition in Arabidopsis. Plant Cell Environ., 2017. 40(9): p. 1849-1860 [PMID:28556304] Yoshiyama KO,Kaminoyama K,Sakamoto T,Kimura S Increased Phosphorylation of Ser-Gln Sites on SUPPRESSOR OF GAMMA RESPONSE1 Strengthens the DNA Damage Response in Arabidopsis thaliana. Plant Cell, 2017. 29(12): p. 3255-3268 [PMID:29208704] Johnson RA, et al. SUPPRESSOR OF GAMMA RESPONSE1 Links DNA Damage Response to Organ Regeneration. Plant Physiol., 2018. 176(2): p. 1665-1675 [PMID:29222192] Ogita N, et al. Identifying the target genes of SUPPRESSOR OF GAMMA RESPONSE 1, a master transcription factor controlling DNA damage response in Arabidopsis. Plant J., 2018. 94(3): p. 439-453 [PMID:29430765] Cao X, et al. Roles of MSH2 and MSH6 in cadmium-induced G2/M checkpoint arrest in Arabidopsis roots. Chemosphere, 2018. 201: p. 586-594 [PMID:29533809]