PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Bv8_184600_qgwa.t1
Organism
Beta vulgaris
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; Caryophyllales; Chenopodiaceae; Betoideae; Beta
Family MYB_related
Protein Properties Length: 518aa    MW: 58818.4 Da    PI: 6.035
Description MYB_related family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Bv8_184600_qgwa.t1genomeTBVRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding409.2e-13104146346
                         SS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHH CS
     Myb_DNA-binding   3 rWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqk 46 
                          W ++E+ ll+++ +++G g+W+ +a+++g ++  +qc++++++
  Bv8_184600_qgwa.t1 104 DWNADEEILLLEGLEMYGLGNWAEVAEHVG-TKNKEQCINHYRS 146
                         6*****************************.***********96 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PIRSFPIRSF0250241.3E-14732517IPR016827Transcriptional adaptor 2
SMARTSM002912.4E-114186IPR000433Zinc finger, ZZ-type
PfamPF005691.1E-94385IPR000433Zinc finger, ZZ-type
SuperFamilySSF578502.0E-1545108No hitNo description
PROSITE profilePS5013510.884588IPR000433Zinc finger, ZZ-type
CDDcd023351.02E-264593No hitNo description
PROSITE patternPS0135704774IPR000433Zinc finger, ZZ-type
SuperFamilySSF466892.17E-1397151IPR009057Homeodomain-like
PROSITE profilePS5129322.545100152IPR017884SANT domain
SMARTSM007176.3E-12101150IPR001005SANT/Myb domain
PfamPF002492.8E-12104146IPR001005SANT/Myb domain
Gene3DG3DSA:1.10.10.601.0E-8104147IPR009057Homeodomain-like
CDDcd001677.34E-6120147No hitNo description
PROSITE profilePS5093410.278432518IPR007526SWIRM domain
SuperFamilySSF466897.53E-17436515IPR009057Homeodomain-like
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006357Biological Processregulation of transcription from RNA polymerase II promoter
GO:0016573Biological Processhistone acetylation
GO:0003677Molecular FunctionDNA binding
GO:0005515Molecular Functionprotein binding
GO:0008270Molecular Functionzinc ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 518 aa     Download sequence    Send to blast
MGRSRAHFDE DPTQRSRRKK NASSGENIES ALGGQGTGDG KKALYHCNYC NKDISGRIRI  60
KCAMCPDFDL CIECFSVGAE VTPHKSNHTY RVMDSLSFPL ISPDWNADEE ILLLEGLEMY  120
GLGNWAEVAE HVGTKNKEQC INHYRSVYLN SPFFPLPDMS HVVGKNRNEL LAMAKENSED  180
RKGSTLFGDH IVKTEPTFSP SRIKVEELQK GGLSGSRLLS VQNSDSQVNP IGKKPPKEEE  240
SSLVSLSGFS LKRREFDPEY DIDAEQLLAE MEFKDADTED ERELKLRVLR IYSKRLDERN  300
RRKDFILERN LLYPSPFEKD LSPEEKTICR RYDPFMRFHS KEEHEDMLQS VIAEHRTRKR  360
ILELEEARAA GCRTSAEADK YFELKRKREA EAIARRANEA TQLGPASQMG QNTAMASEAG  420
KDPVSLIHGQ GQATFISAND LDIGRYPGEE LLSEAEKQLC HETKIPPHLY LKMQETISVK  480
IFSGNVTSNL DAHSLFDIEP EKIDRIYDML IRKGIAPP
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
6cw2_C5e-40451605120Transcriptional adapter 2
6cw3_E4e-40451605120Transcriptional adapter 2
6cw3_G4e-40451605120Transcriptional adapter 2
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtRequired for the function of some acidic activation domains, which activate transcription from a distant site. The exact mechanism of action is not yet known (By similarity). ADA2 stimulates the acetyltransferase activity of GCN5 on free histones or nucleosomes, probably by opening up the promoter region. Mediates auxin and cytokinin signals in the control of cell proliferation and might be involved in repression of a freezing tolerance pathway at warm temperature (PubMed:12615937, PubMed:12747832). Involved in the positive regulation of salt-induced gene expression by maintaining locus-specific acetylation of histones H4 and H3 (PubMed:21193996). {ECO:0000250, ECO:0000269|PubMed:12615937, ECO:0000269|PubMed:12747832, ECO:0000269|PubMed:21193996}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010686640.10.0PREDICTED: transcriptional adapter ADA2b
SwissprotQ9ATB40.0TAD2B_ARATH; Transcriptional adapter ADA2b
TrEMBLA0A0K9QN560.0A0A0K9QN56_SPIOL; Transcriptional adapter
STRINGXP_010686640.10.0(Beta vulgaris)
Publications ? help Back to Top
  1. Vlachonasios KE,Thomashow MF,Triezenberg SJ
    Disruption mutations of ADA2b and GCN5 transcriptional adaptor genes dramatically affect Arabidopsis growth, development, and gene expression.
    Plant Cell, 2003. 15(3): p. 626-38
    [PMID:12615937]
  2. Sieberer T,Hauser MT,Seifert GJ,Luschnig C
    PROPORZ1, a putative Arabidopsis transcriptional adaptor protein, mediates auxin and cytokinin signals in the control of cell proliferation.
    Curr. Biol., 2003. 13(10): p. 837-42
    [PMID:12747832]
  3. Kerschen A,Napoli CA,Jorgensen RA,Müller AE
    Effectiveness of RNA interference in transgenic plants.
    FEBS Lett., 2004. 566(1-3): p. 223-8
    [PMID:15147899]
  4. Hark AT, et al.
    Two Arabidopsis orthologs of the transcriptional coactivator ADA2 have distinct biological functions.
    Biochim. Biophys. Acta, 2009. 1789(2): p. 117-24
    [PMID:18929690]
  5. Anzola JM, et al.
    Putative Arabidopsis transcriptional adaptor protein (PROPORZ1) is required to modulate histone acetylation in response to auxin.
    Proc. Natl. Acad. Sci. U.S.A., 2010. 107(22): p. 10308-13
    [PMID:20479223]
  6. Kaldis A,Tsementzi D,Tanriverdi O,Vlachonasios KE
    Arabidopsis thaliana transcriptional co-activators ADA2b and SGF29a are implicated in salt stress responses.
    Planta, 2011. 233(4): p. 749-62
    [PMID:21193996]
  7. Vlachonasios KE,Kaldis A,Nikoloudi A,Tsementzi D
    The role of transcriptional coactivator ADA2b in Arabidopsis abiotic stress responses.
    Plant Signal Behav, 2011. 6(10): p. 1475-8
    [PMID:21897124]
  8. Heyndrickx KS,Vandepoele K
    Systematic identification of functional plant modules through the integration of complementary data sources.
    Plant Physiol., 2012. 159(3): p. 884-901
    [PMID:22589469]
  9. Kazama D,Kurusu T,Mitsuda N,Ohme-Takagi M,Tada Y
    Involvement of elevated proline accumulation in enhanced osmotic stress tolerance in Arabidopsis conferred by chimeric repressor gene silencing technology.
    Plant Signal Behav, 2014. 9(3): p. e28211
    [PMID:24614501]
  10. Kim JY,Oh JE,Noh YS,Noh B
    Epigenetic control of juvenile-to-adult phase transition by the Arabidopsis SAGA-like complex.
    Plant J., 2015. 83(3): p. 537-45
    [PMID:26095998]
  11. Kazama D, et al.
    Identification of Chimeric Repressors that Confer Salt and Osmotic Stress Tolerance in Arabidopsis.
    Plants (Basel), 2013. 2(4): p. 769-85
    [PMID:27137403]
  12. Simon MK,Skinner DJ,Gallagher TL,Gasser CS
    Integument Development in Arabidopsis Depends on Interaction of YABBY Protein INNER NO OUTER with Coactivators and Corepressors.
    Genetics, 2017. 207(4): p. 1489-1500
    [PMID:28971961]
  13. Lai J, et al.
    The Transcriptional Coactivator ADA2b Recruits a Structural Maintenance Protein to Double-Strand Breaks during DNA Repair in Plants.
    Plant Physiol., 2018. 176(4): p. 2613-2622
    [PMID:29463775]
  14. Kotak J, et al.
    The histone acetyltransferase GCN5 and the transcriptional coactivator ADA2b affect leaf development and trichome morphogenesis in Arabidopsis.
    Planta, 2018. 248(3): p. 613-628
    [PMID:29846775]