PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Bostr.26326s0040.1.p

Organism

Boechera stricta

Taxonomic ID

72658

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Boechereae; Boechera

Family

HSF

Protein Properties

Length: 350aa MW: 39247.1 Da PI: 4.8912

Description

HSF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Bostr.26326s0040.1.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HSF_DNA-bind	116.2	2e-36	45	136	2	102
HHHHHHHHHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE---SSBTTTTXTTSEEEEESXXXXXX CS HSF_DNA-bind 2 FlkklyeiledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYgFkkvkdeekkskskekiweFkhksFkkgk 90 Fl+k+ye++ed+++++++sws+ nsfvv+d+++f++++Lp+yFkhsnf+SF+RQLn+YgF+kv+ ++ weF+++ F +g+ Bostr.26326s0040.1.p 45 FLTKTYEMVEDPATDTVVSWSNGRNSFVVWDSHKFSTTLLPRYFKHSNFSSFIRQLNTYGFRKVDPDR---------WEFANEGFLAGQ 124 9**************************************************************999.........******** PP XXXXXXXXXXXX CS HSF_DNA-bind 91 kellekikrkks 102 k+ll++ikr+++ Bostr.26326s0040.1.p 125 KHLLKNIKRRRN 136 *******986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF46785	6.67E-36	41	134	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM00415	6.7E-61	41	134	IPR000232	Heat shock factor (HSF)-type, DNA-binding
Gene3D	G3DSA:1.10.10.10	3.8E-39	41	134	IPR011991	Winged helix-turn-helix DNA-binding domain
PRINTS	PR00056	2.6E-19	45	68	IPR000232	Heat shock factor (HSF)-type, DNA-binding
Pfam	PF00447	3.9E-32	45	134	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	2.6E-19	83	95	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PROSITE pattern	PS00434	0	84	108	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	2.6E-19	96	108	IPR000232	Heat shock factor (HSF)-type, DNA-binding

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009644	Biological Process	response to high light intensity
GO:0010200	Biological Process	response to chitin
GO:0010286	Biological Process	heat acclimation
GO:0034605	Biological Process	cellular response to heat
GO:0034620	Biological Process	cellular response to unfolded protein
GO:0042542	Biological Process	response to hydrogen peroxide
GO:0045893	Biological Process	positive regulation of transcription, DNA-templated
GO:0071456	Biological Process	cellular response to hypoxia
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding
GO:0044212	Molecular Function	transcription regulatory region DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 350 aa Download sequence Send to blast
MEQQKVEIEE ETVTFAGSAA ASSSVGSSLS PRPMEGLNET GPPPFLTKTY EMVEDPATDT 60 VVSWSNGRNS FVVWDSHKFS TTLLPRYFKH SNFSSFIRQL NTYGFRKVDP DRWEFANEGF 120 LAGQKHLLKN IKRRRNMGLQ NVNQQGSGSG SGMSCVEVGQ YGFDGEVERL KRDHGVLVAE 180 VVRLRQQQHS SKSQVAAMEQ RLLTTEKRQQ QMMTFLAKAL NNPNFVQQFA LMSKEKKSLF 240 GLGVGRKRRL TSTPSLGTME ENLLHDQGFD RMRDDMETLL AAAIDDESSN LIPTKEEQCL 300 EAMNSMMEDS IIEAELDVKV EDLVGSPLDW DSQDLHDMVD QMGFLGSEP*

Sequence ? help Back to Top

Protein Sequence Length: 350 aa Download sequence Send to blast

MEQQKVEIEE ETVTFAGSAA ASSSVGSSLS PRPMEGLNET GPPPFLTKTY EMVEDPATDT  60
VVSWSNGRNS FVVWDSHKFS TTLLPRYFKH SNFSSFIRQL NTYGFRKVDP DRWEFANEGF  120
LAGQKHLLKN IKRRRNMGLQ NVNQQGSGSG SGMSCVEVGQ YGFDGEVERL KRDHGVLVAE  180
VVRLRQQQHS SKSQVAAMEQ RLLTTEKRQQ QMMTFLAKAL NNPNFVQQFA LMSKEKKSLF  240
GLGVGRKRRL TSTPSLGTME ENLLHDQGFD RMRDDMETLL AAAIDDESSN LIPTKEEQCL  300
EAMNSMMEDS IIEAELDVKV EDLVGSPLDW DSQDLHDMVD QMGFLGSEP*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5d5u_B	6e-26	36	134	17	129	Heat shock factor protein 1
5d5v_B	6e-26	36	134	17	129	Heat shock factor protein 1
5d5v_D	6e-26	36	134	17	129	Heat shock factor protein 1
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Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	127	133	LKNIKRR

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional activator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE). Involved in heat stress responses. Seems to be involved in other environmental stress responses. Activates ascorbate peroxidase 2 (APX2) in addition to several heat shock protein (HSPs). {ECO:0000269\|PubMed:16649111, ECO:0000269\|PubMed:17059409, ECO:0000269\|PubMed:17085506}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Bostr.26326s0040.1.p

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By heat stress, high light and hydrogen peroxide (H(2)O(2)). {ECO:0000269\|PubMed:16649111, ECO:0000269\|PubMed:17059409, ECO:0000269\|PubMed:17085506}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AK118744	0.0	AK118744.1 Arabidopsis thaliana At2g26150 mRNA for putative heat shock transcription factor, complete cds, clone: RAFL21-09-G23.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_010472641.1	0.0	PREDICTED: heat stress transcription factor A-2 isoform X1
Swissprot	O80982	0.0	HSFA2_ARATH; Heat stress transcription factor A-2
TrEMBL	R0HI88	0.0	R0HI88_9BRAS; Uncharacterized protein
STRING	Bostr.26326s0040.1.p	0.0	(Boechera stricta)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM11672	27	32

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G26150.1	0.0	heat shock transcription factor A2

Link Out ? help Back to Top
Phytozome	Bostr.26326s0040.1.p

Publications ? help Back to Top
Liu HC,Charng YY Common and distinct functions of Arabidopsis class A1 and A2 heat shock factors in diverse abiotic stress responses and development. Plant Physiol., 2013. 163(1): p. 276-90 [PMID:23832625] Jung HS, et al. Subset of heat-shock transcription factors required for the early response of Arabidopsis to excess light. Proc. Natl. Acad. Sci. U.S.A., 2013. 110(35): p. 14474-9 [PMID:23918368] Chauhan H,Khurana N,Agarwal P,Khurana JP,Khurana P A seed preferential heat shock transcription factor from wheat provides abiotic stress tolerance and yield enhancement in transgenic Arabidopsis under heat stress environment. PLoS ONE, 2013. 8(11): p. e79577 [PMID:24265778] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Weng M, et al. Histone chaperone ASF1 is involved in gene transcription activation in response to heat stress in Arabidopsis thaliana. Plant Cell Environ., 2014. 37(9): p. 2128-38 [PMID:24548003] Jang YH, et al. A homolog of splicing factor SF1 is essential for development and is involved in the alternative splicing of pre-mRNA in Arabidopsis thaliana. Plant J., 2014. 78(4): p. 591-603 [PMID:24580679] Stief A, et al. Arabidopsis miR156 Regulates Tolerance to Recurring Environmental Stress through SPL Transcription Factors. Plant Cell, 2014. 26(4): p. 1792-1807 [PMID:24769482] Dobrá J, et al. The impact of heat stress targeting on the hormonal and transcriptomic response in Arabidopsis. Plant Sci., 2015. 231: p. 52-61 [PMID:25575991] Yamauchi Y,Kunishima M,Mizutani M,Sugimoto Y Reactive short-chain leaf volatiles act as powerful inducers of abiotic stress-related gene expression. Sci Rep, 2015. 5: p. 8030 [PMID:25619826] Shi H, et al. Melatonin induces class A1 heat-shock factors (HSFA1s) and their possible involvement of thermotolerance in Arabidopsis. J. Pineal Res., 2015. 58(3): p. 335-42 [PMID:25711624] Mueller SP,Krause DM,Mueller MJ,Fekete A Accumulation of extra-chloroplastic triacylglycerols in Arabidopsis seedlings during heat acclimation. J. Exp. Bot., 2015. 66(15): p. 4517-26 [PMID:25977236] Nie S,Yue H,Xing D A Potential Role for Mitochondrial Produced Reactive Oxygen Species in Salicylic Acid-Mediated Plant Acquired Thermotolerance. Plant Physiol., 2016. [PMID:26099269] Nguyen AH, et al. Loss of Arabidopsis 5'-3' Exoribonuclease AtXRN4 Function Enhances Heat Stress Tolerance of Plants Subjected to Severe Heat Stress. Plant Cell Physiol., 2015. 56(9): p. 1762-72 [PMID:26136597] Hu Z, et al. Histone acetyltransferase GCN5 is essential for heat stress-responsive gene activation and thermotolerance in Arabidopsis. Plant J., 2015. 84(6): p. 1178-91 [PMID:26576681] Lämke J,Brzezinka K,Bäurle I HSFA2 orchestrates transcriptional dynamics after heat stress in Arabidopsis thaliana. Transcription, 2016. 7(4): p. 111-4 [PMID:27383578] Wang X,Huang W,Liu J,Yang Z,Huang B Molecular regulation and physiological functions of a novel FaHsfA2c cloned from tall fescue conferring plant tolerance to heat stress. Plant Biotechnol. J., 2017. 15(2): p. 237-248 [PMID:27500592] Chen ST,He NY,Chen JH,Guo FQ Identification of core subunits of photosystem II as action sites of HSP21, which is activated by the GUN5-mediated retrograde pathway in Arabidopsis. Plant J., 2017. 89(6): p. 1106-1118 [PMID:27943531] Kataoka R,Takahashi M,Suzuki N Coordination between bZIP28 and HSFA2 in the regulation of heat response signals in Arabidopsis. Plant Signal Behav, 2017. 12(11): p. e1376159 [PMID:28873003] Wang X,Zhuang L,Shi Y,Huang B Up-Regulation of HSFA2c and HSPs by ABA Contributing to Improved Heat Tolerance in Tall Fescue and Arabidopsis. Int J Mol Sci, 2018. [PMID:28914758] Llamas E,Pulido P,Rodriguez-Concepcion M Interference with plastome gene expression and Clp protease activity in Arabidopsis triggers a chloroplast unfolded protein response to restore protein homeostasis. PLoS Genet., 2017. 13(9): p. e1007022 [PMID:28937985] Li X, et al. Plastid Translation Elongation Factor Tu Is Prone to Heat-Induced Aggregation Despite Its Critical Role in Plant Heat Tolerance. Plant Physiol., 2018. 176(4): p. 3027-3045 [PMID:29444814]