PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Bostr.13671s0164.1.p
Organism
Boechera stricta
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Boechereae; Boechera
Family bHLH
Protein Properties Length: 461aa    MW: 50819.9 Da    PI: 6.5117
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Bostr.13671s0164.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH361.3e-11280322754
                           HHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHH CS
                   HLH   7 erErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksL 54 
                           ++ErrRR+++N+++  Lr+++Pk +      K++ a+iL  A++Y+k+L
  Bostr.13671s0164.1.p 280 MAERRRRKKLNDRLYMLRSVVPKiS------KMDRASILGDAIDYLKEL 322
                           79*********************66......****************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5088815.866273322IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474591.96E-16276346IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003534.2E-14279328IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000103.0E-9279322IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000836.72E-13280326No hitNo description
Gene3DG3DSA:4.10.280.103.2E-15280336IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profilePS516718.512388460IPR002912ACT domain
CDDcd048738.89E-7389430No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0008152Biological Processmetabolic process
GO:0010444Biological Processguard mother cell differentiation
GO:0050826Biological Processresponse to freezing
GO:0016597Molecular Functionamino acid binding
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 461 aa     Download sequence    Send to blast
MNGDGVWLDG AGERSSEVDN GEAASWVRNP DEDWFNNPPP PSQHLQDSQI LHSNNQNDFR  60
FNGGFPLNPS ENLLLLLQQS IDSSSSAPLH PFTLDAASQQ HQHQQQQEQS FLATKACIAS  120
LLNVPTSNNN TFDEFGFDSG FLGQQFHGHQ TPKSMNFAGL NHSGPDFLTF RSIPAPENST  180
GSCGLSPLFS NRAKVLKPLE VLASSGSQPT LFQKRAAMRQ SSSSKICNSE SSSEIKKSSY  240
QREIDDTSTG IIDISGLNYE SDELNNNKGK KKGMPAKNLM AERRRRKKLN DRLYMLRSVV  300
PKISKMDRAS ILGDAIDYLK ELLQRINDIH TELESTPPSS SSLHPITPTP QTLSYRVKEE  360
LCPSSSLPSP KGQQPRVEVR LREGKAVNIH MFCGRRPGLL LSTMRALDNL GLDVQQAVIS  420
CFNGFALDVF RAEQCQEDHD VLPEQIKAVL LDTAGYAGLI *
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1269287KKKGMPAKNLMAERRRRKK
2281288ERRRRKKL
Functional Description ? help Back to Top
Source Description
UniProtMediates stomatal differentiation in the epidermis probably by controlling successive roles of SPCH, MUTE, and FAMA (PubMed:18641265). Functions as a dimer with SPCH during stomatal initiation (PubMed:18641265, PubMed:28507175). {ECO:0000269|PubMed:18641265, ECO:0000269|PubMed:28507175}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapBostr.13671s0164.1.p
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAK1180110.0AK118011.1 Arabidopsis thaliana At1g12860 mRNA for putative bHLH transcription factor (bHLH033), complete cds, clone: RAFL19-21-N13.
GenBankBT0053770.0BT005377.1 Arabidopsis thaliana At1g12860 mRNA, complete cds.
GenBankEU3696700.0EU369670.1 Arabidopsis thaliana bHLH protein (SCREAM2) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006307455.10.0transcription factor SCREAM2
SwissprotQ9LPW30.0SCRM2_ARATH; Transcription factor SCREAM2
TrEMBLR0ISL00.0R0ISL0_9BRAS; Uncharacterized protein
STRINGBostr.13671s0164.1.p0.0(Boechera stricta)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM19522782
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G12860.10.0bHLH family protein
Publications ? help Back to Top
  1. Tarasov VA,Khadeeva NV,Mel'nik VA,Ezhova TA,Shestakov SV
    The Atlg12860 gene of Arabidopsis thaliana determines cathelicidin-like antimicrobial activity.
    Dokl. Biol. Sci., 2009.
    [PMID:19760875]
  2. Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH
    Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature.
    Differentiation, 2010. 80(1): p. 1-8
    [PMID:20219281]
  3. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  4. Emmerstorfer A, et al.
    Over-expression of ICE2 stabilizes cytochrome P450 reductase in Saccharomyces cerevisiae and Pichia pastoris.
    Biotechnol J, 2015. 10(4): p. 623-35
    [PMID:25641738]
  5. Lee HG,Seo PJ
    The MYB96-HHP module integrates cold and abscisic acid signaling to activate the CBF-COR pathway in Arabidopsis.
    Plant J., 2015. 82(6): p. 962-77
    [PMID:25912720]
  6. Raissig MT,Abrash E,Bettadapur A,Vogel JP,Bergmann DC
    Grasses use an alternatively wired bHLH transcription factor network to establish stomatal identity.
    Proc. Natl. Acad. Sci. U.S.A., 2016. 113(29): p. 8326-31
    [PMID:27382177]
  7. Fu ZW,Wang YL,Lu YT,Yuan TT
    Nitric oxide is involved in stomatal development by modulating the expression of stomatal regulator genes in Arabidopsis.
    Plant Sci., 2016. 252: p. 282-289
    [PMID:27717464]
  8. de Marcos A, et al.
    A Mutation in the bHLH Domain of the SPCH Transcription Factor Uncovers a BR-Dependent Mechanism for Stomatal Development.
    Plant Physiol., 2017. 174(2): p. 823-842
    [PMID:28507175]