PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Brast09G075600.1.p
Organism
Brachypodium stacei
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Pooideae; Brachypodieae; Brachypodium
Family E2F/DP
Protein Properties Length: 440aa    MW: 48045.5 Da    PI: 6.6384
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Brast09G075600.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP85.54e-27128193171
             E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                         r+++sL+llt+kf++ll+++e+giv+ln++a+ L   dv  ++RRiYDi+NVLe+++liekk kn+i+wkg
  Brast09G075600.1.p 128 RYDNSLGLLTRKFINLLKQAEDGIVDLNSAAEIL---DV--QKRRIYDITNVLEGIGLIEKKIKNRIHWKG 193
                         689*******************************...**..****************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.102.7E-28125195IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013727.7E-35128193IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467851.22E-17128191IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023199.2E-24130193IPR003316E2F/DP family, winged-helix DNA-binding domain
CDDcd146608.44E-42203309No hitNo description
SuperFamilySSF1440741.31E-29205309No hitNo description
PfamPF164219.4E-29208307IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005667Cellular Componenttranscription factor complex
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 440 aa     Download sequence    Send to blast
MSGGGRPQVA RKVVHSVQRR VPLAPGRPPI AVPSEYHRFP VPLPSAAAAA ASRGRVRGDI  60
EVGIVTMKPL KRKAPCRERL GSPLMTPVSG KASRTYKSKA KCSKSGPQTP ISNAGSPGNP  120
LTPAGSCRYD NSLGLLTRKF INLLKQAEDG IVDLNSAAEI LDVQKRRIYD ITNVLEGIGL  180
IEKKIKNRIH WKGLNDSGSN SDNTISVLQT EVENLNLQEE VLDEHISEIH EKIREFTEEE  240
SNQRWLYLTE DDIKGLPCFQ NGTLIAIKAP HGTTLEVPDP DEAGDYIKRM YRIVIRSTRG  300
SIDLYLVSKS DEKIEEVDVA TPPRQADLAT PTSVKGFGAI EAGQSSRAND MLPNIQYIRK  360
TPDLNAQDFG GVAITPEVDT DADYWLLTDG DDVSITDMWK TAPEVQWDQF LAKEETTPCA  420
LKQQAAVVGK PTVVGPTHG*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A1e-23123194274PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapBrast09G075600.1.p
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_003581217.10.0transcription factor E2FA isoform X1
SwissprotQ9FNY01e-110E2FA_ARATH; Transcription factor E2FA
TrEMBLA0A0Q3E4020.0A0A0Q3E402_BRADI; Uncharacterized protein
STRINGTraes_2DL_BD8048C15.10.0(Triticum aestivum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP62537148
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G36010.11e-105E2F transcription factor 3
Publications ? help Back to Top
  1. Magyar Z, et al.
    Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes.
    EMBO J., 2012. 31(6): p. 1480-93
    [PMID:22307083]