PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | XP_009150868.1 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica
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Family | E2F/DP | ||||||||
Protein Properties | Length: 413aa MW: 46560.2 Da PI: 7.7804 | ||||||||
Description | E2F/DP family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | E2F_TDP | 66.6 | 3.3e-21 | 32 | 121 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....................dvknkrRRiYDilNVLealnliekkekneirwkg 71 rk+ksL+ll+++fl+l+++ +++ l++++++L v +rRRiYDi+NVLe+++++++++kn+++wkg XP_009150868.1 32 RKQKSLGLLCTNFLALYNRHGIETIGLDDASSKLGFSpltsffcallgfefrfwnlvaGV--ERRRIYDIVNVLESVGVLTRRAKNQYTWKG 121 79*****************999************6669******************9888..****************************98 PP | |||||||
2 | E2F_TDP | 79.3 | 3.5e-25 | 188 | 268 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 r+eksL+lltq+f+kl+ +s+++i++l+e+ak L+ + +++k+RR+YDi+NVL+++nliek ++k++++w g XP_009150868.1 188 RREKSLGLLTQNFIKLFICSQATIISLDEAAKLLLGDahntsIMRTKVRRLYDIANVLSSMNLIEKthtldSRKPAFKWLG 268 689**************************************999************************9999*******87 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Gene3D | G3DSA:1.10.10.10 | 3.6E-23 | 28 | 122 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SuperFamily | SSF46785 | 1.27E-12 | 31 | 119 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 1.4E-21 | 32 | 121 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Pfam | PF02319 | 2.1E-18 | 33 | 121 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Gene3D | G3DSA:1.10.10.10 | 2.4E-23 | 185 | 269 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 3.2E-32 | 188 | 268 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Pfam | PF02319 | 5.7E-20 | 190 | 268 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
SuperFamily | SSF46785 | 1.72E-13 | 190 | 269 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0006355 | Biological Process | regulation of transcription, DNA-templated | ||||
GO:0032876 | Biological Process | negative regulation of DNA endoreduplication | ||||
GO:0005634 | Cellular Component | nucleus | ||||
GO:0005667 | Cellular Component | transcription factor complex | ||||
GO:0003677 | Molecular Function | DNA binding | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 413 aa Download sequence Send to blast |
MSDLPPEKTN MELSSSSSMP GSSSSLHHSY SRKQKSLGLL CTNFLALYNR HGIETIGLDD 60 ASSKLGFSPL TSFFCALLGF EFRFWNLVAG VERRRIYDIV NVLESVGVLT RRAKNQYTWK 120 GFAAIPAALK ELQEEGAKDT FHRFYVNENV KGSDDEDDEE ESSSQPLSTS QTDTSKPSLP 180 DSSKIDNRRE KSLGLLTQNF IKLFICSQAT IISLDEAAKL LLGDAHNTSI MRTKVRRLYD 240 IANVLSSMNL IEKTHTLDSR KPAFKWLGYN GEPTFTLSSD LMMQAESKKR VFGTDLSNVS 300 VKRSKTHDSA TERSLKMKHH AIAESSYNRI FDAHESRHGS RGYEFGPFAP ATGTYPTAPL 360 EDSSKRAFDV ENLVSDYRPS YQNQVLKDLF GHYMDAWKSW YSEVTQKNPS QHH |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
4yo2_A | 3e-36 | 31 | 260 | 3 | 228 | Transcription factor E2F8 |
Search in ModeBase |
Expression -- Description ? help Back to Top | ||||||
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Source | Description | |||||
Uniprot | DEVELOPMENTAL STAGE: Expressed in a cell cycle-dependent manner. Not detected during early S phase. Expressed at both the G1/S and S/G2 transitions, with a peak during G2. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:18787127}. | |||||
Uniprot | TISSUE SPECIFICITY: Expressed exclusively in mitotically dividing cells. Highly expressed in young leaves and mature flowers. Lower expression in young stalk and in young and mature flowers. {ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366}. |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Inhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}. |
Binding Motif ? help Back to Top | |||
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Motif ID | Method | Source | Motif file |
MP00397 | DAP | Transfer from AT3G48160 | Download |
Cis-element ? help Back to Top | |
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Source | Link |
PlantRegMap | XP_009150868.1 |
Regulation -- PlantRegMap ? help Back to Top | ||||||
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Source | Upstream Regulator | Target Gene | ||||
PlantRegMap | Retrieve | Retrieve |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_009150874.1 | 0.0 | PREDICTED: E2F transcription factor-like E2FE | ||||
Refseq | XP_013716161.1 | 0.0 | E2F transcription factor-like E2FE | ||||
Swissprot | Q8LSZ4 | 0.0 | E2FE_ARATH; E2F transcription factor-like E2FE | ||||
TrEMBL | A0A398AWG1 | 0.0 | A0A398AWG1_BRACM; Uncharacterized protein | ||||
STRING | Bo1g074680.1 | 0.0 | (Brassica oleracea) |
Orthologous Group ? help Back to Top | |||
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Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Malvids | OGEM6304 | 27 | 43 |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT3G48160.2 | 0.0 | DP-E2F-like 1 |
Publications ? help Back to Top | |||
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