PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

XP_009149418.1

Organism

Brassica rapa

Taxonomic ID

3711

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica

Family

BES1

Protein Properties

Length: 331aa MW: 36176.2 Da PI: 9.8295

Description

BES1 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_009149418.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	DUF822	199.3	1.3e-61	18	148	2	141
DUF822 2 gsgrkptwkErEnnkrRERrRRaiaakiyaGLRaqGnyklpkraDnneVlkALcreAGwvvedDGttyrkgskpleeaeaagssasaspesslqs 96 +++rkp+w+ErEnn+rRERrRRa+aakiy GLRaqGny+lpk++DnneVlkALc eAGwvve+DGttyrkg kpl ++agss++a+p ss+ XP_009149418.1 18 ATRRKPSWRERENNRRRERRRRAVAAKIYNGLRAQGNYNLPKHCDNNEVLKALCSEAGWVVEEDGTTYRKGHKPL-PGDMAGSSSRATPYSSSY- 110 689**********************************************************************.9******9999966. PP DUF822 97 slkssalaspvesysaspksssfpspssldsislasaasllpvls 141 + s ++sp+ sy+ sp+sssfpsps+ d+is+ ++p+l+ XP_009149418.1 111 --NQSPFESPILSYQVSPSSSSFPSPSRGDNIST-----IFPFLR 148 ..899***********************9954.....455555 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF05687	1.4E-58	19	142	IPR008540	BES1/BZR1 plant transcription factor, N-terminal

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009742	Biological Process	brassinosteroid mediated signaling pathway
GO:0042742	Biological Process	defense response to bacterium
GO:0045892	Biological Process	negative regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0005829	Cellular Component	cytosol
GO:0001046	Molecular Function	core promoter sequence-specific DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 331 aa Download sequence Send to blast
MTSDGATSTS AAAAAALATR RKPSWREREN NRRRERRRRA VAAKIYNGLR AQGNYNLPKH 60 CDNNEVLKAL CSEAGWVVEE DGTTYRKGHK PLPGDMAGSS SRATPYSSSY NQSPFESPIL 120 SYQVSPSSSS FPSPSRGDNI STIFPFLRNG GIPSSLPPLR ISNSAPVTPP VSSPTSKHPK 180 PLPTWESFTK QSMAIAAKQS MSSFNYPFYA VSAPASPTHH RQFNAPATIP ECDESDASTV 240 DSGHWISFQK FSQQQQPFHG VSSAVPASPT FNLVKPPVPQ RLSPNTAGIQ EIGQSSEFKF 300 ENRQVTPWEG ERIHDVAMED LELTLGNTKG R

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5zd4_A	3e-35	20	102	371	453	Maltose-binding periplasmic protein,Protein BRASSINAZOLE-RESISTANT 1
5zd4_B	3e-35	20	102	371	453	Maltose-binding periplasmic protein,Protein BRASSINAZOLE-RESISTANT 1
5zd4_C	3e-35	20	102	371	453	Maltose-binding periplasmic protein,Protein BRASSINAZOLE-RESISTANT 1
5zd4_D	3e-35	20	102	371	453	Maltose-binding periplasmic protein,Protein BRASSINAZOLE-RESISTANT 1
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Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	19	38	RRKPSWRERENNRRRERRRR

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
Bra.6561	0.0	flower\| leaf\| root

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Ubiquitously expressed in cotyledons, leaves, hypocotyls and roots. {ECO:0000269\|PubMed:12007405}.

Functional Description ? help Back to Top
Source	Description
UniProt	Positive regulator of brassinosteroid (BR) signaling. Transcription factor that activates target gene expression by binding specifically to the DNA sequence 5'-CANNTG-3'(E box) through its N-terminal domain. Can bind individually to the promoter as a homodimer or synergistically as a heterodimer with BIM1, BIM2 or BIM3. The C-terminal domain is probably involved in transcriptional activation (PubMed:12007405, PubMed:15680330, PubMed:18467490, PubMed:19170933). Recruits the transcription elongation factor IWS1 to control BR-regulated gene expression (PubMed:20139304). Forms a trimeric complex with IWS1 and ASHH2/SDG8 to regulate BR-regulated gene expression (PubMed:24838002). Promotes quiescent center (QC) self-renewal by cell divisions in the primary root. Binds to the E-boxes of the BRAVO promoter to repress its expression (PubMed:24981610). {ECO:0000269\|PubMed:12007405, ECO:0000269\|PubMed:15680330, ECO:0000269\|PubMed:18467490, ECO:0000269\|PubMed:19170933, ECO:0000269\|PubMed:20139304, ECO:0000269\|PubMed:24838002, ECO:0000269\|PubMed:24981610}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00073	ChIP-chip	Transfer from AT1G19350	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	XP_009149418.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AC189356	0.0	AC189356.2 Brassica rapa subsp. pekinensis cultivar Inbred line 'Chiifu' clone KBrB043O20, complete sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009149416.1	0.0	PREDICTED: protein BRASSINAZOLE-RESISTANT 2
Refseq	XP_009149417.1	0.0	PREDICTED: protein BRASSINAZOLE-RESISTANT 2
Refseq	XP_009149418.1	0.0	PREDICTED: protein BRASSINAZOLE-RESISTANT 2
Refseq	XP_013641895.1	0.0	protein BRASSINAZOLE-RESISTANT 2
Swissprot	Q9LN63	1e-180	BZR2_ARATH; Protein BRASSINAZOLE-RESISTANT 2
TrEMBL	A0A078IMH1	0.0	A0A078IMH1_BRANA; BnaA06g13620D protein
TrEMBL	A0A397Z6X3	0.0	A0A397Z6X3_BRACM; Uncharacterized protein
TrEMBL	M4EAC5	0.0	M4EAC5_BRARP; Uncharacterized protein
STRING	Bra025733.1-P	0.0	(Brassica rapa)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G19350.3	1e-143	BES1 family protein

Publications ? help Back to Top
Salazar-Henao JE,Lehner R,Betegón-Putze I,Vilarrasa-Blasi J,Caño-Delgado AI BES1 regulates the localization of the brassinosteroid receptor BRL3 within the provascular tissue of the Arabidopsis primary root. J. Exp. Bot., 2016. 67(17): p. 4951-61 [PMID:27511026] Nolan T, et al. Identification of Brassinosteroid Target Genes by Chromatin Immunoprecipitation Followed by High-Throughput Sequencing (ChIP-seq) and RNA-Sequencing. Methods Mol. Biol., 2017. 1564: p. 63-79 [PMID:28124247] Ye H, et al. RD26 mediates crosstalk between drought and brassinosteroid signalling pathways. Nat Commun, 2017. 8: p. 14573 [PMID:28233777] Nolan TM, et al. Selective Autophagy of BES1 Mediated by DSK2 Balances Plant Growth and Survival. Dev. Cell, 2017. 41(1): p. 33-46.e7 [PMID:28399398] Yang M, et al. SINAT E3 Ligases Control the Light-Mediated Stability of the Brassinosteroid-Activated Transcription Factor BES1 in Arabidopsis. Dev. Cell, 2017. 41(1): p. 47-58.e4 [PMID:28399399] Chen J, et al. Arabidopsis WRKY46, WRKY54, and WRKY70 Transcription Factors Are Involved in Brassinosteroid-Regulated Plant Growth and Drought Responses. Plant Cell, 2017. 29(6): p. 1425-1439 [PMID:28576847] Yang M,Wang X Multiple Ways of BES1/BZR1 Degradation to Decode Distinct Developmental and Environmental Cues in Plants. Mol Plant, 2017. 10(7): p. 915-917 [PMID:28629641] Saito M,Kondo Y,Fukuda H BES1 and BZR1 Redundantly Promote Phloem and Xylem Differentiation. Plant Cell Physiol., 2018. 59(3): p. 590-600 [PMID:29385529] Liang T, et al. UVR8 Interacts with BES1 and BIM1 to Regulate Transcription and Photomorphogenesis in Arabidopsis. Dev. Cell, 2018. 44(4): p. 512-523.e5 [PMID:29398622]