PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

XP_009117546.1

Organism

Brassica rapa

Taxonomic ID

3711

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica

Family

BES1

Protein Properties

Length: 319aa MW: 34918.8 Da PI: 9.9081

Description

BES1 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_009117546.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	DUF822	193.6	7.1e-60	15	154	2	149
DUF822 2 gsgrkptwkErEnnkrRERrRRaiaakiyaGLRaqGnyklpkraDnneVlkALcreAGwvvedDGttyrkgskpleeaeaagssasaspesslqs 96 +++rkp+w+ErEnn+rRER+RRa+aakiy GLRaqGn++lp ++DnneVlkALc eAGwvve+DGttyrkg kpl ++agss++a+ ss++ XP_009117546.1 15 ATRRKPSWRERENNRRRERKRRAVAAKIYNGLRAQGNFNLPRHCDNNEVLKALCSEAGWVVEEDGTTYRKGHKPL-PDDMAGSSSRATAYSSYN- 107 689**********************************************************************.999*********99. PP DUF822 97 slkssalaspvesysaspksssfpspssldsislasaasllpvlsvlslvsss 149 s ++sp+ sy+asp+sssfpsp d+ +++ +++p+l++ + +ss XP_009117546.1 108 ---QSPFESPILSYQASPSSSSFPSPRGGDTHNIS---TIFPFLRNGGINPSS 154 ...889***********************9995...899999988876665 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF05687	3.6E-57	16	140	IPR008540	BES1/BZR1 plant transcription factor, N-terminal

Sequence ? help Back to Top
Protein Sequence Length: 319 aa Download sequence Send to blast
MTSEGAMLTS AAAMATRRKP SWRERENNRR RERKRRAVAA KIYNGLRAQG NFNLPRHCDN 60 NEVLKALCSE AGWVVEEDGT TYRKGHKPLP DDMAGSSSRA TAYSSYNQSP FESPILSYQA 120 SPSSSSFPSP RGGDTHNIST IFPFLRNGGI NPSSLPPLRI SNSAPVTPPV SSPTSRNPKP 180 LPTWESLTKQ AMANAARQSV SSFNYPFYAV SAPTSPTHHR QFNAPATIPE CDESDSSTTD 240 SGHWISFQKF SQQQFRGGFA VPPSPTFNLV KPPLPQQLSS NIAAAQEIGS QVKPWEGERI 300 HDVAMEDLEL TLGNSKGRS

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5zd4_A	2e-33	17	99	371	453	Maltose-binding periplasmic protein,Protein BRASSINAZOLE-RESISTANT 1
5zd4_B	2e-33	17	99	371	453	Maltose-binding periplasmic protein,Protein BRASSINAZOLE-RESISTANT 1
5zd4_C	2e-33	17	99	371	453	Maltose-binding periplasmic protein,Protein BRASSINAZOLE-RESISTANT 1
5zd4_D	2e-33	17	99	371	453	Maltose-binding periplasmic protein,Protein BRASSINAZOLE-RESISTANT 1
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Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	16	35	RRKPSWRERENNRRRERKRR

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Ubiquitously expressed in cotyledons, leaves, hypocotyls and roots. {ECO:0000269\|PubMed:12007405}.

Functional Description ? help Back to Top
Source	Description
UniProt	Positive regulator of brassinosteroid (BR) signaling. Transcription factor that activates target gene expression by binding specifically to the DNA sequence 5'-CANNTG-3'(E box) through its N-terminal domain. Can bind individually to the promoter as a homodimer or synergistically as a heterodimer with BIM1, BIM2 or BIM3. The C-terminal domain is probably involved in transcriptional activation (PubMed:12007405, PubMed:15680330, PubMed:18467490, PubMed:19170933). Recruits the transcription elongation factor IWS1 to control BR-regulated gene expression (PubMed:20139304). Forms a trimeric complex with IWS1 and ASHH2/SDG8 to regulate BR-regulated gene expression (PubMed:24838002). Promotes quiescent center (QC) self-renewal by cell divisions in the primary root. Binds to the E-boxes of the BRAVO promoter to repress its expression (PubMed:24981610). {ECO:0000269\|PubMed:12007405, ECO:0000269\|PubMed:15680330, ECO:0000269\|PubMed:18467490, ECO:0000269\|PubMed:19170933, ECO:0000269\|PubMed:20139304, ECO:0000269\|PubMed:24838002, ECO:0000269\|PubMed:24981610}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	XP_009117546.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009117543.1	0.0	PREDICTED: protein BRASSINAZOLE-RESISTANT 2-like
Refseq	XP_009117544.1	0.0	PREDICTED: protein BRASSINAZOLE-RESISTANT 2-like
Refseq	XP_009117545.1	0.0	PREDICTED: protein BRASSINAZOLE-RESISTANT 2-like
Refseq	XP_013664647.1	0.0	protein BRASSINAZOLE-RESISTANT 2-like
Swissprot	Q9LN63	1e-165	BZR2_ARATH; Protein BRASSINAZOLE-RESISTANT 2
TrEMBL	A0A078G5C8	0.0	A0A078G5C8_BRANA; BnaA09g44210D protein
TrEMBL	A0A397YB44	0.0	A0A397YB44_BRACM; Uncharacterized protein
TrEMBL	A0A3P5Y899	0.0	A0A3P5Y899_BRACM; Uncharacterized protein
TrEMBL	M4EQK6	0.0	M4EQK6_BRARP; Uncharacterized protein
STRING	Bra031077.1-P	0.0	(Brassica rapa)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G19350.6	1e-140	BES1 family protein

Publications ? help Back to Top
Salazar-Henao JE,Lehner R,Betegón-Putze I,Vilarrasa-Blasi J,Caño-Delgado AI BES1 regulates the localization of the brassinosteroid receptor BRL3 within the provascular tissue of the Arabidopsis primary root. J. Exp. Bot., 2016. 67(17): p. 4951-61 [PMID:27511026] Nolan T, et al. Identification of Brassinosteroid Target Genes by Chromatin Immunoprecipitation Followed by High-Throughput Sequencing (ChIP-seq) and RNA-Sequencing. Methods Mol. Biol., 2017. 1564: p. 63-79 [PMID:28124247] Ye H, et al. RD26 mediates crosstalk between drought and brassinosteroid signalling pathways. Nat Commun, 2017. 8: p. 14573 [PMID:28233777] Nolan TM, et al. Selective Autophagy of BES1 Mediated by DSK2 Balances Plant Growth and Survival. Dev. Cell, 2017. 41(1): p. 33-46.e7 [PMID:28399398] Yang M, et al. SINAT E3 Ligases Control the Light-Mediated Stability of the Brassinosteroid-Activated Transcription Factor BES1 in Arabidopsis. Dev. Cell, 2017. 41(1): p. 47-58.e4 [PMID:28399399] Chen J, et al. Arabidopsis WRKY46, WRKY54, and WRKY70 Transcription Factors Are Involved in Brassinosteroid-Regulated Plant Growth and Drought Responses. Plant Cell, 2017. 29(6): p. 1425-1439 [PMID:28576847] Yang M,Wang X Multiple Ways of BES1/BZR1 Degradation to Decode Distinct Developmental and Environmental Cues in Plants. Mol Plant, 2017. 10(7): p. 915-917 [PMID:28629641] Saito M,Kondo Y,Fukuda H BES1 and BZR1 Redundantly Promote Phloem and Xylem Differentiation. Plant Cell Physiol., 2018. 59(3): p. 590-600 [PMID:29385529] Liang T, et al. UVR8 Interacts with BES1 and BIM1 to Regulate Transcription and Photomorphogenesis in Arabidopsis. Dev. Cell, 2018. 44(4): p. 512-523.e5 [PMID:29398622]