PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_013626087.1
Organism
Brassica oleracea
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica
Family MIKC_MADS
Protein Properties Length: 305aa    MW: 34778.4 Da    PI: 10.0234
Description MIKC_MADS family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_013626087.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1SRF-TF99.41.4e-3175125151
                     S---SHHHHHHHHHHHHHHHHHHHHHHHHHHT-EEEEEEE-TTSEEEEEE- CS
          SRF-TF   1 krienksnrqvtfskRrngilKKAeELSvLCdaevaviifsstgklyeyss 51 
                     krien++nrqvtf+kRrng+lKKA+ELSvLCdaeva+i+fss+g+lyeys+
  XP_013626087.1  75 KRIENTTNRQVTFCKRRNGLLKKAYELSVLCDAEVALIVFSSRGRLYEYSN 125
                     79***********************************************95 PP
2K-box97.61.9e-321422423100
           K-box   3 kssgksleeakaeslqqelakLkkeienLqreqRhllGedLesLslkeLqqLeqqLekslkkiRskKnellleqieelqkk...ekelqeenkaL 94 
                     +s++ s++e +a+++qqe+akL+++i ++q+++R+l+Ge ++s+s keL++Le +L++s+++iRskKnell+++i+++qk+   e +l+++n+ L
  XP_013626087.1 142 NSNTGSVAEINAQYYQQESAKLRQQIISIQNSNRQLMGETIGSMSPKELRNLEGRLDRSINRIRSKKNELLFAEIDYMQKRfeqEVDLHSDNQLL 236
                     45555699***********************************************************************985446689******* PP

           K-box  95 rkklee 100
                     r+k++e
  XP_013626087.1 237 RAKIAE 242
                     ***986 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM004328.1E-4167126IPR002100Transcription factor, MADS-box
PROSITE profilePS5006633.31967127IPR002100Transcription factor, MADS-box
CDDcd002652.08E-4568141No hitNo description
SuperFamilySSF554554.58E-3368140IPR002100Transcription factor, MADS-box
PROSITE patternPS00350069123IPR002100Transcription factor, MADS-box
PRINTSPR004041.1E-326989IPR002100Transcription factor, MADS-box
PfamPF003191.3E-2676123IPR002100Transcription factor, MADS-box
PRINTSPR004041.1E-3289104IPR002100Transcription factor, MADS-box
PRINTSPR004041.1E-32104125IPR002100Transcription factor, MADS-box
PfamPF014861.1E-24152240IPR002487Transcription factor, K-box
PROSITE profilePS5129714.757153246IPR002487Transcription factor, K-box
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0048366Biological Processleaf development
GO:0048440Biological Processcarpel development
GO:0048443Biological Processstamen development
GO:0048497Biological Processmaintenance of floral organ identity
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 305 aa     Download sequence    Send to blast
MYIPNLFTST TLPSIFCKFS KSHTFHKIIF PRNNPFLFAH LPLSPTAANT AYQMELGGDS  60
SPQRKTAGRG KIEIKRIENT TNRQVTFCKR RNGLLKKAYE LSVLCDAEVA LIVFSSRGRL  120
YEYSNNSVKG TIERYKKAIS DNSNTGSVAE INAQYYQQES AKLRQQIISI QNSNRQLMGE  180
TIGSMSPKEL RNLEGRLDRS INRIRSKKNE LLFAEIDYMQ KRFEQEVDLH SDNQLLRAKI  240
AENERNNPSM NLMPGGSNYE QIIPPPQTNS QPFDSRNYFQ VAALQPNNQH YSSAGRQDLT  300
ALQLV
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1egw_A2e-1968135168MADS BOX TRANSCRIPTION ENHANCER FACTOR 2, POLYPEPTIDE A
1egw_B2e-1968135168MADS BOX TRANSCRIPTION ENHANCER FACTOR 2, POLYPEPTIDE A
1egw_C2e-1968135168MADS BOX TRANSCRIPTION ENHANCER FACTOR 2, POLYPEPTIDE A
1egw_D2e-1968135168MADS BOX TRANSCRIPTION ENHANCER FACTOR 2, POLYPEPTIDE A
3kov_A3e-1968135168Myocyte-specific enhancer factor 2A
3kov_B3e-1968135168Myocyte-specific enhancer factor 2A
3kov_I3e-1968135168Myocyte-specific enhancer factor 2A
3kov_J3e-1968135168Myocyte-specific enhancer factor 2A
3mu6_A2e-1968135168Myocyte-specific enhancer factor 2A
3mu6_B2e-1968135168Myocyte-specific enhancer factor 2A
3mu6_C2e-1968135168Myocyte-specific enhancer factor 2A
3mu6_D2e-1968135168Myocyte-specific enhancer factor 2A
3p57_A3e-1968135168Myocyte-specific enhancer factor 2A
3p57_B3e-1968135168Myocyte-specific enhancer factor 2A
3p57_C3e-1968135168Myocyte-specific enhancer factor 2A
3p57_D3e-1968135168Myocyte-specific enhancer factor 2A
3p57_I3e-1968135168Myocyte-specific enhancer factor 2A
3p57_J3e-1968135168Myocyte-specific enhancer factor 2A
6c9l_E3e-1968135269Myocyte-specific enhancer factor 2B
6c9l_F3e-1968135269Myocyte-specific enhancer factor 2B
Search in ModeBase
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Detected early in the floral meristem but mostly expressed in stamen and carpel primordia. {ECO:0000269|PubMed:1675158}.
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor involved in the control of organ identity during the early development of flowers. Is required for normal development of stamens and carpels in the wild-type flower. Plays a role in maintaining the determinacy of the floral meristem. Acts as C class cadastral protein by repressing the A class floral homeotic genes like APETALA1. Forms a heterodimer via the K-box domain with either SEPALATTA1/AGL2, SEPALATTA2/AGL4, SEPALLATA3/AGL9 or AGL6 that could be involved in genes regulation during floral meristem development. Controls AHL21/GIK, a multifunctional chromatin modifier in reproductive organ patterning and differentiation (PubMed:19956801). Induces microsporogenesis through the activation of SPL/NZZ (PubMed:15254538). {ECO:0000269|PubMed:15254538, ECO:0000269|PubMed:19956801}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00609ChIP-seqTransfer from AT4G18960Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapXP_013626087.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Negatively regulated by the A class floral homeotic protein APETALA2 and by other repressors like LEUNIG, SEUSS, SAP or CURLY LEAF. Positively regulated by both LEAFY and APETALA1. Repressed by silencing mediated by polycomb group (PcG) protein complex containing EMF1 and EMF2. Up-regulated by HUA2. {ECO:0000269|PubMed:10198637, ECO:0000269|PubMed:11058164, ECO:0000269|PubMed:1675158, ECO:0000269|PubMed:17794879, ECO:0000269|PubMed:18281509, ECO:0000269|PubMed:19783648, ECO:0000269|PubMed:9783581}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankKC9843000.0KC984300.2 Brassica oleracea var. viridis AG mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_013626087.10.0PREDICTED: floral homeotic protein AGAMOUS-like isoform X1
RefseqXP_013626089.10.0PREDICTED: floral homeotic protein AGAMOUS-like isoform X2
RefseqXP_013715948.20.0floral homeotic protein AGAMOUS-like isoform X1
RefseqXP_022563502.10.0floral homeotic protein AGAMOUS-like isoform X2
SwissprotP178391e-171AG_ARATH; Floral homeotic protein AGAMOUS
TrEMBLA0A3P6BA730.0A0A3P6BA73_BRAOL; Uncharacterized protein
STRINGXP_010436489.10.0(Camelina sativa)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM61812237
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G18960.11e-161MIKC_MADS family protein
Publications ? help Back to Top
  1. Huang Z, et al.
    APETALA2 antagonizes the transcriptional activity of AGAMOUS in regulating floral stem cells in Arabidopsis thaliana.
    New Phytol., 2017. 215(3): p. 1197-1209
    [PMID:27604611]
  2. Rong XF, et al.
    Type-B ARRs Control Carpel Regeneration Through Mediating AGAMOUS Expression in Arabidopsis.
    Plant Cell Physiol., 2018. 59(4): p. 756-764
    [PMID:29186581]
  3. Uemura A, et al.
    Regulation of floral meristem activity through the interaction of AGAMOUS, SUPERMAN, and CLAVATA3 in Arabidopsis.
    Plant Reprod, 2018. 31(1): p. 89-105
    [PMID:29218596]