PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

XP_013599323.1

Organism

Brassica oleracea

Taxonomic ID

3712

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica

Family

C2H2

Protein Properties

Length: 464aa MW: 51271.6 Da PI: 6.6055

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_013599323.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	14.1	0.00014	125	147	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++Cp+Cg +F++ ++ +H ++ XP_013599323.1 125 FECPICGNPFKTEEEVSVHVESC 147 89*****************9876 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50157	8.725	125	152	IPR007087	Zinc finger, C2H2
CDD	cd09212	4.65E-21	178	267	No hit	No description
SuperFamily	SSF143503	5.49E-18	182	246	IPR018997	PUB domain
SMART	SM00580	2.6E-23	184	251	IPR018997	PUB domain
Pfam	PF09409	1.5E-17	184	250	IPR018997	PUB domain
SuperFamily	SSF54236	2.84E-12	330	439	IPR029071	Ubiquitin-related domain
PROSITE profile	PS50033	10.161	355	439	IPR001012	UBX domain
Gene3D	G3DSA:3.10.20.90	1.5E-7	355	438	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0050832	Biological Process	defense response to fungus
GO:0005515	Molecular Function	protein binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 464 aa Download sequence Send to blast
MDDVKDKLKG FMKKVNLSSS SGKFKGSGRV LGSSSSAPVN PIQNRFNPPQ SSKPKPNPNQ 60 TPRPAKPSPS PSPSAALPEK PVSSGSQKKP DPDPVRAPPQ DGFDPFGAFI TSSNRSQNGY 120 SLNMFECPIC GNPFKTEEEV SVHVESCLGE DTTTNGDEAS SEEKDKSEVE KLVVVYLSGK 180 PSESSVDVLL RLLKNIVKEP ENGKFRKIRM SNAKIKEAIG DVAGGVELLE LVGFELKEEN 240 DEIWAVMDVP GGDQTQLINE VVGMLEKRKI EMSRKDEVLP VEPVAAAPKK IDREIRVFFS 300 VAENVASKIE VPDSFYSLSA DEIKREADLR RKKIAESQLL IPRSYKEKQA KAARKRYKRS 360 MIRVQFPDGV VLQGVFAPWE PTFALYEFVS SALKEPSLQF ELLDPVLVKR RVIPHTPAPG 420 QKPRTLEDEE LVPSALIKFR PIETASLVYT GLCNELLEIS EPLT

Sequence ? help Back to Top

Protein Sequence Length: 464 aa Download sequence Send to blast

MDDVKDKLKG FMKKVNLSSS SGKFKGSGRV LGSSSSAPVN PIQNRFNPPQ SSKPKPNPNQ  60
TPRPAKPSPS PSPSAALPEK PVSSGSQKKP DPDPVRAPPQ DGFDPFGAFI TSSNRSQNGY  120
SLNMFECPIC GNPFKTEEEV SVHVESCLGE DTTTNGDEAS SEEKDKSEVE KLVVVYLSGK  180
PSESSVDVLL RLLKNIVKEP ENGKFRKIRM SNAKIKEAIG DVAGGVELLE LVGFELKEEN  240
DEIWAVMDVP GGDQTQLINE VVGMLEKRKI EMSRKDEVLP VEPVAAAPKK IDREIRVFFS  300
VAENVASKIE VPDSFYSLSA DEIKREADLR RKKIAESQLL IPRSYKEKQA KAARKRYKRS  360
MIRVQFPDGV VLQGVFAPWE PTFALYEFVS SALKEPSLQF ELLDPVLVKR RVIPHTPAPG  420
QKPRTLEDEE LVPSALIKFR PIETASLVYT GLCNELLEIS EPLT

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5ifw_A	2e-12	310	439	23	146	Tether containing UBX domain for GLUT4
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	352	360	ARKRYKRSM

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
Bol.14037	0.0	leaf

Functional Description ? help Back to Top
Source	Description
UniProt	Facilitates the interaction of SYP31 and CDC48A, thereby regulating an CDC48A membrane-associated function (Ref.8). Appears to act as a negative regulator mediating the powdery mildew-plant interaction (PubMed:19176722, PubMed:23301616). {ECO:0000269\|PubMed:19176722, ECO:0000269\|PubMed:23301616, ECO:0000269\|Ref.8}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	XP_013599323.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced in response to powdery mildew and by benzothiadiazole (BTH) treatment. {ECO:0000269\|PubMed:19176722}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AK118911	1e-173	AK118911.1 Arabidopsis thaliana At2g01650 mRNA for unknown protein, complete cds, clone: RAFL21-25-I03.
GenBank	AY572782	1e-173	AY572782.1 Arabidopsis thaliana CDC48-interacting UBX-domain protein (PUX2) mRNA, complete cds.
GenBank	BT005408	1e-173	BT005408.1 Arabidopsis thaliana clone U51117 unknown protein (At2g01650) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_013599323.1	0.0	PREDICTED: plant UBX domain-containing protein 2
Swissprot	Q9ZU93	0.0	PUX2_ARATH; Plant UBX domain-containing protein 2
TrEMBL	A0A0D3DA54	0.0	A0A0D3DA54_BRAOL; Uncharacterized protein
TrEMBL	A0A3P6EXP1	0.0	A0A3P6EXP1_BRAOL; Uncharacterized protein
STRING	Bo7g078630.1	0.0	(Brassica oleracea)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM9835	16	18

Publications ? help Back to Top
Suzuki T,Park H,Till EA,Lennarz WJ The PUB domain: a putative protein-protein interaction domain implicated in the ubiquitin-proteasome pathway. Biochem. Biophys. Res. Commun., 2001. 287(5): p. 1083-7 [PMID:11587532] Rancour DM,Park S,Knight SD,Bednarek SY Plant UBX domain-containing protein 1, PUX1, regulates the oligomeric structure and activity of arabidopsis CDC48. J. Biol. Chem., 2004. 279(52): p. 54264-74 [PMID:15498773] Chandran D,Rickert J,Cherk C,Dotson BR,Wildermuth MC Host cell ploidy underlying the fungal feeding site is a determinant of powdery mildew growth and reproduction. Mol. Plant Microbe Interact., 2013. 26(5): p. 537-45 [PMID:23301616]