PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_013588523.1
Organism
Brassica oleracea
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica
Family HD-ZIP
Protein Properties Length: 710aa    MW: 77502.4 Da    PI: 6.8126
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_013588523.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox59.55.3e-193590156
                    TT--SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS
        Homeobox  1 rrkRttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56
                    +++ +++t++q+++Le+ F+++++p+ ++r  L+k+lgL  rq+k+WFqNrR++ k
  XP_013588523.1 35 KKRYHRHTAQQIQRLESSFRECPHPDDKQRNLLSKELGLAPRQIKFWFQNRRTQLK 90
                    688999**********************************************9877 PP
2START160.61.2e-502244452206
                     HHHHHHHHHHHHHHHC-TT-EEEE...EXCCTTEEEEEEESSS.......SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-S....EEEEEE CS
           START   2 laeeaaqelvkkalaeepgWvkss...esengdevlqkfeeskv......dsgealrasgvvdmvlallveellddkeqWdetla....kaetle 83 
                     +a++a+qel++++  +ep+W++s    e +n   +   f++s +       ++ea+r sg+v+m+++ lv  ++d + +W e ++    + +tl+
  XP_013588523.1 224 IALTAMQELLRLVHTNEPLWSRSDgcgEVLNLGSYENVFPRSSNrgknhnVRIEASRSSGIVFMNAMSLVDMFMDCA-KWAELFPsivaASKTLA 317
                     6899**********************9677777776667666667778989**************************.*******99999***** PP

                     EECTT.......EEEEEEEEXXTTXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--.-TTSEE-EESSEEEEEEEECTCEEEEEEEE-E CS
           START  84 vissg.......galqlmvaelqalsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppesssvvRaellpSgiliepksnghskvtwvehv 170
                     v+ssg       gal+lm+ e+ +lsplv+ R+f  +Ry++q ++g+w++v vS   +q+++ +s++ R   +pSg+li++++ng+skvtwveh+
  XP_013588523.1 318 VVSSGmgggtheGALHLMYEEMEVLSPLVAtREFCELRYCQQIEQGSWIVVNVSYHLPQFVS-HSHSYR---FPSGCLIQDMPNGYSKVTWVEHT 408
                     **************************************************************.999999...*********************** PP

                     E--SSXX.HHHHHHHHHHHHHHHHHHHHHHTXXXXXX CS
           START 171 dlkgrlp.hwllrslvksglaegaktwvatlqrqcek 206
                     + +++ p h+++r +v++g+a+ga +wv tlqr ce+
  XP_013588523.1 409 ETEEKEPvHEMYRDMVHKGIAFGAERWVTTLQRMCER 445
                     ***********************************97 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.601.8E-202394IPR009057Homeodomain-like
SuperFamilySSF466897.94E-192996IPR009057Homeodomain-like
PROSITE profilePS5007117.5243292IPR001356Homeobox domain
SMARTSM003891.2E-173396IPR001356Homeobox domain
PfamPF000461.8E-163590IPR001356Homeobox domain
CDDcd000861.69E-183593No hitNo description
PROSITE patternPS0002706790IPR017970Homeobox, conserved site
PROSITE profilePS5084848.274214448IPR002913START domain
SuperFamilySSF559614.53E-33215447No hitNo description
CDDcd088753.91E-103218444No hitNo description
SMARTSM002341.4E-40223445IPR002913START domain
PfamPF018528.1E-44224445IPR002913START domain
Gene3DG3DSA:3.30.530.201.8E-7275444IPR023393START-like domain
SuperFamilySSF559613.71E-18464697No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009828Biological Processplant-type cell wall loosening
GO:0010091Biological Processtrichome branching
GO:0005634Cellular Componentnucleus
GO:0000976Molecular Functiontranscription regulatory region sequence-specific DNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0008289Molecular Functionlipid binding
Sequence ? help Back to Top
Protein Sequence    Length: 710 aa     Download sequence    Send to blast
MSFVVGGSGS GGGDGGDGGG GGRQRHDASE TDRKKKRYHR HTAQQIQRLE SSFRECPHPD  60
DKQRNLLSKE LGLAPRQIKF WFQNRRTQLK AQHERADNSA LKAENDKIRC ENIAIREALK  120
HAICPNCGGP PVSEDPYLDE QKLRMENAHL REELERMSTV ASKYMGRPIS SHISTLHPMH  180
ISPLDLSMTS LAGGPSLDFD LLPGSSMSSN FAVSDMDKPI MNDIALTAMQ ELLRLVHTNE  240
PLWSRSDGCG EVLNLGSYEN VFPRSSNRGK NHNVRIEASR SSGIVFMNAM SLVDMFMDCA  300
KWAELFPSIV AASKTLAVVS SGMGGGTHEG ALHLMYEEME VLSPLVATRE FCELRYCQQI  360
EQGSWIVVNV SYHLPQFVSH SHSYRFPSGC LIQDMPNGYS KVTWVEHTET EEKEPVHEMY  420
RDMVHKGIAF GAERWVTTLQ RMCERFASLL APAASSLGGV IPSPEGKRSM MRLAHRMVSN  480
YCISVSRSNN TRSTVVAELN EVGVRVTAHK SPEPNGTILS AATTFWLPNS PQNVFNFLKD  540
ERTRPQWDVL SNSNAVQEVA HIANGSHPGC CISVLRASSA SQSNNMLILQ ETSIDSSGAL  600
VVYSPVDLSA LNIAMNGDDT SYIPILSSGF AISPDGNRNS PSAEQGGASS SSGYGGGGSL  660
ITVGFQIMVS NLPSAKLNME SVETVNNLIG TTVHQIKTGL NNCPSASTTA
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: During embryo development, expressed in all cells at the 4- and 16-cell embryo stages. Expression is restricted to the protoderm from the globular stage onward. {ECO:0000269|PubMed:25564655}.
UniprotTISSUE SPECIFICITY: Expressed in apical meristems and young epidermal tissue including trichomes and stipules. Expressed in lateral root tips, the L1 layer of apical inflorescence meristems and early flower primordia, carpel and petal epidermis, stigma papillae, ovule primordia, nucellus and embryo. {ECO:0000269|PubMed:16778018}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor which acts as positive regulator of drought stress tolerance. Can transactivate CIPK3, NCED3 and ERECTA (PubMed:18451323). Transactivates several cell-wall-loosening protein genes by directly binding to HD motifs in their promoters. These target genes play important roles in coordinating cell-wall extensibility with root development and growth (PubMed:24821957). Transactivates CYP74A/AOS, AOC3, OPR3 and 4CLL5/OPCL1 genes by directly binding to HD motifs in their promoters. These target genes are involved in jasmonate (JA) biosynthesis, and JA signaling affects root architecture by activating auxin signaling, which promotes lateral root formation (PubMed:25752924). Acts as negative regulator of trichome branching (PubMed:16778018, PubMed:24824485). Required for the establishment of giant cell identity on the abaxial side of sepals (PubMed:23095885). May regulate cell differentiation and proliferation during root and shoot meristem development (PubMed:25564655). {ECO:0000269|PubMed:16778018, ECO:0000269|PubMed:18451323, ECO:0000269|PubMed:23095885, ECO:0000269|PubMed:24821957, ECO:0000269|PubMed:24824485, ECO:0000269|PubMed:25564655, ECO:0000269|PubMed:25752924}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00232DAPTransfer from AT1G73360Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapXP_013588523.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_013588523.10.0PREDICTED: homeobox-leucine zipper protein HDG11-like
SwissprotQ9FX310.0HDG11_ARATH; Homeobox-leucine zipper protein HDG11
TrEMBLA0A0D3CWW80.0A0A0D3CWW8_BRAOL; Uncharacterized protein
STRINGBo6g087810.10.0(Brassica oleracea)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM30042665
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G73360.10.0homeodomain GLABROUS 11
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Khosla A, et al.
    HD-Zip Proteins GL2 and HDG11 Have Redundant Functions in Arabidopsis Trichomes, and GL2 Activates a Positive Feedback Loop via MYB23.
    Plant Cell, 2014. 26(5): p. 2184-2200
    [PMID:24824485]
  3. Horstman A, et al.
    AIL and HDG proteins act antagonistically to control cell proliferation.
    Development, 2015. 142(3): p. 454-64
    [PMID:25564655]
  4. Cai XT,Xu P,Wang Y,Xiang CB
    Activated expression of AtEDT1/HDG11 promotes lateral root formation in Arabidopsis mutant edt1 by upregulating jasmonate biosynthesis.
    J Integr Plant Biol, 2015. 57(12): p. 1017-30
    [PMID:25752924]
  5. Yu LH, et al.
    Arabidopsis EDT1/HDG11 improves drought and salt tolerance in cotton and poplar and increases cotton yield in the field.
    Plant Biotechnol. J., 2016. 14(1): p. 72-84
    [PMID:25879154]
  6. Zhu Z, et al.
    Overexpression of AtEDT1/HDG11 in Chinese Kale (Brassica oleracea var. alboglabra) Enhances Drought and Osmotic Stress Tolerance.
    Front Plant Sci, 2016. 7: p. 1285
    [PMID:27625663]
  7. Liu Y, et al.
    Overexpression of AtEDT1 promotes root elongation and affects medicinal secondary metabolite biosynthesis in roots of transgenic Salvia miltiorrhiza.
    Protoplasma, 2017. 254(4): p. 1617-1625
    [PMID:27915455]
  8. Ueda M, et al.
    Transcriptional integration of paternal and maternal factors in the Arabidopsis zygote.
    Genes Dev., 2017. 31(6): p. 617-627
    [PMID:28404632]
  9. Lung SC, et al.
    Arabidopsis ACYL-COA-BINDING PROTEIN1 interacts with STEROL C4-METHYL OXIDASE1-2 to modulate gene expression of homeodomain-leucine zipper IV transcription factors.
    New Phytol., 2018. 218(1): p. 183-200
    [PMID:29288621]
  10. Zheng G, et al.
    Over-Expression of Arabidopsis EDT1 Gene Confers Drought Tolerance in Alfalfa (Medicago sativa L.).
    Front Plant Sci, 2017. 8: p. 2125
    [PMID:29326737]