PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

XP_013588419.1

Organism

Brassica oleracea

Taxonomic ID

3712

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica

Family

ERF

Protein Properties

Length: 210aa MW: 23842.3 Da PI: 4.7024

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_013588419.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	59.8	6.3e-19	73	123	2	55
AP2 2 gykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 y+GVr+++ +g+++AeIrd + ng r++lg+f +aeeAa a+++a+ +++g XP_013588419.1 73 SYRGVRRRP-WGKFAAEIRDSTRNG--IRVWLGTFESAEEAALAYDQAAFSMRG 123 69*****.******44465..***********************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
CDD	cd00018	1.44E-29	72	132	No hit	No description
Pfam	PF00847	1.1E-13	73	123	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	2.22E-22	73	132	IPR016177	DNA-binding domain
SMART	SM00380	2.0E-37	73	137	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	23.156	73	131	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	1.1E-30	73	132	IPR001471	AP2/ERF domain
PRINTS	PR00367	1.8E-10	74	85	IPR001471	AP2/ERF domain
PRINTS	PR00367	1.8E-10	97	113	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0006952	Biological Process	defense response
GO:0009873	Biological Process	ethylene-activated signaling pathway
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 210 aa Download sequence Send to blast
MDPYFVQSSF SAFSPEYSPE SFSSSSSNNY SLPFNENDSE EMLLYGLIEQ STQQNLPVKT 60 EEEAGTSRKP EKSYRGVRRR PWGKFAAEIR DSTRNGIRVW LGTFESAEEA ALAYDQAAFS 120 MRGSSAILNF PAERVKESLS EIMYSYEDGC SPVVALKRKH SMRRRMTNRK TKDTDFDHSS 180 VKLDNVVVFE DLGEQYLEEL LGSSENSGAW

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2gcc_A	2e-29	72	131	4	63	ATERF1
3gcc_A	2e-29	72	131	4	63	ATERF1
5wx9_A	7e-29	74	133	15	74	Ethylene-responsive transcription factor ERF096
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Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Ubiquitously expressed, mostly in flowers and rosettes after ethylene treatment. {ECO:0000269\|PubMed:11950980}.

Functional Description ? help Back to Top
Source	Description
UniProt	Acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. Involved in the regulation of gene expression during the plant development, and/or mediated by stress factors and by components of stress signal transduction pathways. Seems to be a key integrator of ethylene and jasmonate signals in the regulation of ethylene/jasmonate-dependent defenses. Can mediate resistance to necrotizing fungi (Botrytis cinerea and Plectosphaerella cucumerina) and to soil borne fungi (Fusarium oxysporum conglutinans and Fusiarium oxysporum lycopersici), but probably not to necrotizing bacteria (Pseudomonas syringae tomato). {ECO:0000269\|PubMed:11950980, ECO:0000269\|PubMed:12060224, ECO:0000269\|PubMed:12509529, ECO:0000269\|PubMed:15242170, ECO:0000269\|PubMed:9851977}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00374	DAP	Transfer from AT3G23240	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	XP_013588419.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by Pseudomonas syringae tomato (both virulent and avirulent avrRpt2 strains), independently of PAD4. Ethylene induction is completely dependent on functional ETHYLENE-INSENSITIVE2 (EIN2), ETHYLENE-INSENSITIVE3 (EIN3), which is itself a transcription factor and CORONATIVE-INSENSITIVE1 (COI1) proteins. Induction by jasmonate, B.cinerea or F.oxysporum as well as the synergistic induction by ethylene and jasmonate requires EIN2 and COI1. Induction by methyl jasmonate (MeJA) is independent of JAR1. Induction by salicylic acid (SA) is dependent on NPR1 but not on PAD4. Seems not to be induced by Alternaria brassicicola. {ECO:0000269\|PubMed:11950980, ECO:0000269\|PubMed:12060224, ECO:0000269\|PubMed:12509529, ECO:0000269\|PubMed:12805630, ECO:0000269\|PubMed:15242170, ECO:0000269\|PubMed:9851977}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AB025608	1e-146	AB025608.1 Arabidopsis thaliana genomic DNA, chromosome 3, TAC clone:K14B15.
GenBank	AF076277	1e-146	AF076277.1 Arabidopsis thaliana ethylene response factor 1 (ERF1) mRNA, complete cds.
GenBank	AF076278	1e-146	AF076278.1 Arabidopsis thaliana ethylene response factor 1 (ERF1) gene, complete cds.
GenBank	AF428390	1e-146	AF428390.1 Arabidopsis thaliana AT3g23240/K14B15_13 mRNA, complete cds.
GenBank	AY133629	1e-146	AY133629.1 Arabidopsis thaliana AT3g23240/K14B15_13 mRNA, complete cds.
GenBank	CP002686	1e-146	CP002686.1 Arabidopsis thaliana chromosome 3, complete sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_013588419.1	1e-155	PREDICTED: ethylene-responsive transcription factor 1B
Refseq	XP_013746854.1	1e-155	ethylene-responsive transcription factor 1B-like
Swissprot	Q8LDC8	1e-120	ERF92_ARATH; Ethylene-responsive transcription factor 1B
TrEMBL	A0A0D3ABA8	1e-152	A0A0D3ABA8_BRAOL; Uncharacterized protein
TrEMBL	A0A3N6US88	1e-153	A0A3N6US88_BRACR; Uncharacterized protein
TrEMBL	A0A3P6FSM8	1e-153	A0A3P6FSM8_BRAOL; Uncharacterized protein
STRING	Bo1g102210.1	1e-153	(Brassica oleracea)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM2275	28	76

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G23240.1	1e-104	ethylene response factor 1

Publications ? help Back to Top
Zarate SI,Kempema LA,Walling LL Silverleaf whitefly induces salicylic acid defenses and suppresses effectual jasmonic acid defenses. Plant Physiol., 2007. 143(2): p. 866-75 [PMID:17189328] Vahabi K,Camehl I,Sherameti I,Oelmüller R Growth of Arabidopsis seedlings on high fungal doses of Piriformospora indica has little effect on plant performance, stress, and defense gene expression in spite of elevated jasmonic acid and jasmonic acid-isoleucine levels in the roots. Plant Signal Behav, 2013. 8(11): p. e26301 [PMID:24047645] Kim HG, et al. GDSL LIPASE1 modulates plant immunity through feedback regulation of ethylene signaling. Plant Physiol., 2013. 163(4): p. 1776-91 [PMID:24170202] Li J,Jia H,Wang J cGMP and ethylene are involved in maintaining ion homeostasis under salt stress in Arabidopsis roots. Plant Cell Rep., 2014. 33(3): p. 447-59 [PMID:24306353] Zhong S, et al. Ethylene-orchestrated circuitry coordinates a seedling's response to soil cover and etiolated growth. Proc. Natl. Acad. Sci. U.S.A., 2014. 111(11): p. 3913-20 [PMID:24599595] Kim HG, et al. GDSL lipase 1 regulates ethylene signaling and ethylene-associated systemic immunity in Arabidopsis. FEBS Lett., 2014. 588(9): p. 1652-8 [PMID:24631536] Schellingen K, et al. Cadmium-induced ethylene production and responses in Arabidopsis thaliana rely on ACS2 and ACS6 gene expression. BMC Plant Biol., 2014. 14: p. 214 [PMID:25082369] Ellouzi H, et al. A comparative study of the early osmotic, ionic, redox and hormonal signaling response in leaves and roots of two halophytes and a glycophyte to salinity. Planta, 2014. 240(6): p. 1299-317 [PMID:25156490] Nguyen AH, et al. Loss of Arabidopsis 5'-3' Exoribonuclease AtXRN4 Function Enhances Heat Stress Tolerance of Plants Subjected to Severe Heat Stress. Plant Cell Physiol., 2015. 56(9): p. 1762-72 [PMID:26136597] Cheng MC,Kuo WC,Wang YM,Chen HY,Lin TP UBC18 mediates ERF1 degradation under light-dark cycles. New Phytol., 2017. 213(3): p. 1156-1167 [PMID:27787902] Timmermann T, et al. Paraburkholderia phytofirmans PsJN Protects Arabidopsis thaliana Against a Virulent Strain of Pseudomonas syringae Through the Activation of Induced Resistance. Mol. Plant Microbe Interact., 2017. 30(3): p. 215-230 [PMID:28118091] Yu Y,Huang R Integration of Ethylene and Light Signaling Affects Hypocotyl Growth in Arabidopsis. Front Plant Sci, 2017. 8: p. 57 [PMID:28174592] Lestari R, et al. Overexpression of Hevea brasiliensis ethylene response factor HbERF-IXc5 enhances growth and tolerance to abiotic stress and affects laticifer differentiation. Plant Biotechnol. J., 2018. 16(1): p. 322-336 [PMID:28626940] Dinolfo MI,Castañares E,Stenglein SA Resistance of Fusarium poae in Arabidopsis leaves requires mainly functional JA and ET signaling pathways. Fungal Biol, 2017. 121(10): p. 841-848 [PMID:28889908]