PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID GSBRNA2T00145752001
Common NameGSBRNA2T00145752001
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica
Family ARF
Protein Properties Length: 851aa    MW: 94678.2 Da    PI: 6.8767
Description ARF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
GSBRNA2T00145752001genomeGenoscopeView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B370.62.1e-22159260199
                          EEEE-..-HHHHTT-EE--HHH.HTT......---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHHHHHHT--TT-EEEEEE CS
                   B3   1 ffkvltpsdvlksgrlvlpkkfaeeh......ggkkeesktltledesgrsWevkliyrkksgryvltkGWkeFvkangLkegDfvvFkl 84 
                          f+k+lt sd++++g +++ +++a+e+      + + + +++l+ +d++  +W++++i+r++++r++l++GW+ Fv++++L +gD ++F  
  GSBRNA2T00145752001 159 FCKTLTASDTSTHGGFSVLRRHADEClppldmSRQ-PPTQELVAKDLHASEWRFRHIFRGQPRRHLLQSGWSVFVSSKRLVAGDAFIFL- 246
                          99*****************************7333.34459************************************************. PP

                          -SSSEE..EEEEE-S CS
                   B3  85 dgrsefelvvkvfrk 99 
                           + +++el+v+v+r+
  GSBRNA2T00145752001 247 -RGENGELRVGVRRA 260
                          .449999*****996 PP

2Auxin_resp120.31.5e-39285367183
           Auxin_resp   1 aahaastksvFevvYnPrastseFvvkvekvekalkvkvsvGmRfkmafetedsserrlsGtvvgvsdldpvrWpnSkWrsLk 83 
                          a+ha+st+++F+v+Y+Pr+s+seF+v+++++ +++k+++s+GmRfkm+fe+e+++e+r++Gt+vg++d+dp+rW +SkWrsLk
  GSBRNA2T00145752001 285 AWHAISTGTMFTVYYKPRTSPSEFIVPFDQYTESVKNNYSIGMRFKMRFEGEEAPEQRFTGTIVGIEDSDPTRWAKSKWRSLK 367
                          89*******************************************************************************96 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:2.40.330.102.6E-40155274IPR015300DNA-binding pseudobarrel domain
SuperFamilySSF1019367.06E-40156288IPR015300DNA-binding pseudobarrel domain
CDDcd100174.71E-20157259No hitNo description
SMARTSM010191.3E-21159261IPR003340B3 DNA binding domain
PROSITE profilePS5086311.35159261IPR003340B3 DNA binding domain
PfamPF023623.0E-20159260IPR003340B3 DNA binding domain
PfamPF065079.3E-37285367IPR010525Auxin response factor
PfamPF023095.4E-5714760IPR033389AUX/IAA domain
PROSITE profilePS5174524.219724808IPR000270PB1 domain
SuperFamilySSF542772.85E-11726801No hitNo description
PfamPF023097.2E-6770809IPR033389AUX/IAA domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009734Biological Processauxin-activated signaling pathway
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0005515Molecular Functionprotein binding
Sequence ? help Back to Top
Protein Sequence    Length: 851 aa     Download sequence    Send to blast
MASSEVSMKG NRGRGENFSS AGYSDPTVAG EAQKTQSNRS VAAERVVDPE AALYRELWHA  60
CAGPLVTVPR QDDRVFYFPQ GHIEQVEAST NQAAEQQMPL YDLPSKILCR VINVDLKAEA  120
DTDEVYAQIT LLPEPVQDEN SIEKEAPPPP PPRFQVHSFC KTLTASDTST HGGFSVLRRH  180
ADECLPPLDM SRQPPTQELV AKDLHASEWR FRHIFRGQPR RHLLQSGWSV FVSSKRLVAG  240
DAFIFLRGEN GELRVGVRRA MRQQGNVPSS VISSHSMHLG VLATAWHAIS TGTMFTVYYK  300
PRTSPSEFIV PFDQYTESVK NNYSIGMRFK MRFEGEEAPE QRFTGTIVGI EDSDPTRWAK  360
SKWRSLKACV RWDETTSIPR PDRVSPWKIE PALSPPALSP VPMPRPKRPR SNLASSTPDS  420
SMRIREGSSK ANMDPLPASG LSRVLQGQEY PTLRTKHVES VECDAPENSV VWQSSTDDDK  480
VDVISASRRY ENWISSGRHG PTCTDLLSGF GTNIEPPHGH QIPFYDRLSS PPSVAARKIL  540
SDQDGKFEYL ANQWMMHSGL SLKLHESPKV PAASDASFQG IGNPNYGEYA LPRAVTTENA  600
AGNWPIRPRA LNYFEEAVHA QAREHVTKRP AVVQEEAAKP RDGNCRLFGI PLVNNVNGTD  660
TTLSQRNNLN DPAGPTQMAS PKVQDLSDQS KGSKSTNDHR EQGRPFPVSK PHPKDVQTKT  720
NSCRSCTKVQ KQGIALGRSV DLSKFQNYEE LVTELDRLFE FNGELMAPKK DWLIVYTDDE  780
NDMMLVGDDP WQEFCCMVRK IFIYTKEEVR KMNPGTLCCR NEEEPVVGEG SDAKDAKSAS  840
NPSLSSAGNS *
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4ldv_A1e-1785239118354Auxin response factor 1
4ldw_A1e-1785239118354Auxin response factor 1
4ldw_B1e-1785239118354Auxin response factor 1
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Bna.23130.0root| seed
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Expressed in the sepals and carpels of young flower buds. At stage 10 of flower development, expression in the carpels becomes restricted to the style. Also expressed in anthers and filaments. At stage 13, expressed in the region at the top of the pedicel, including the abscission zone. Expressed in developing siliques. {ECO:0000269|PubMed:15960614, ECO:0000269|PubMed:16176952}.
UniprotTISSUE SPECIFICITY: Expressed in the whole plant. {ECO:0000269|PubMed:10476078, ECO:0000269|PubMed:15960614}.
Functional Description ? help Back to Top
Source Description
UniProtAuxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Could act as transcriptional activator or repressor. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. Promotes flowering, stamen development, floral organ abscission and fruit dehiscence. Functions independently of ethylene and cytokinin response pathways. May act as a repressor of cell division and organ growth. {ECO:0000269|PubMed:12036261, ECO:0000269|PubMed:15960614, ECO:0000269|PubMed:16176952, ECO:0000269|PubMed:16339187}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapGSBRNA2T00145752001
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAJ7162270.0AJ716227.1 Brassica napus mRNA for putative auxin response factor (ARF2 gene).
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_013718200.10.0auxin response factor 2-like isoform X1
RefseqXP_022553069.10.0auxin response factor 2-like isoform X2
SwissprotQ94JM30.0ARFB_ARATH; Auxin response factor 2
TrEMBLA0A3P6AXS60.0A0A3P6AXS6_BRAOL; Auxin response factor
STRINGBo3g108130.10.0(Brassica oleracea)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM53482647
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G62000.30.0auxin response factor 2
Publications ? help Back to Top
  1. Chao WS,Doğramaci M,Foley ME,Horvath DP,Anderson JV
    Selection and validation of endogenous reference genes for qRT-PCR analysis in leafy spurge (Euphorbia esula).
    PLoS ONE, 2012. 7(8): p. e42839
    [PMID:22916167]
  2. Ozerova LV,Krasnikova MS,Troitsky AV,Solovyev AG,Morozov SY
    TAS3 Genes for small ta-siARF RNAs in plants belonging to subtribe Senecioninae: occurrence of prematurely terminated RNA precursors.
    Mol. Gen. Mikrobiol. Virusol., 2013.
    [PMID:24003511]
  3. Li C, et al.
    Ectopic expression of a maize hybrid down-regulated gene ZmARF25 decreases organ size by affecting cellular proliferation in Arabidopsis.
    PLoS ONE, 2014. 9(4): p. e94830
    [PMID:24756087]
  4. Chalhoub B, et al.
    Plant genetics. Early allopolyploid evolution in the post-Neolithic Brassica napus oilseed genome.
    Science, 2014. 345(6199): p. 950-3
    [PMID:25146293]
  5. Lyons R, et al.
    Fusarium oxysporum triggers tissue-specific transcriptional reprogramming in Arabidopsis thaliana.
    PLoS ONE, 2015. 10(4): p. e0121902
    [PMID:25849296]
  6. Roodbarkelari F,Du F,Truernit E,Laux T
    ZLL/AGO10 maintains shoot meristem stem cells during Arabidopsis embryogenesis by down-regulating ARF2-mediated auxin response.
    BMC Biol., 2015. 13: p. 74
    [PMID:26358077]
  7. Meng LS,Wang ZB,Yao SQ,Liu A
    The ARF2-ANT-COR15A gene cascade regulates ABA-signaling-mediated resistance of large seeds to drought in Arabidopsis.
    J. Cell. Sci., 2015. 128(21): p. 3922-32
    [PMID:26395398]
  8. Zhao S,Zhang ML,Ma TL,Wang Y
    Phosphorylation of ARF2 Relieves Its Repression of Transcription of the K+ Transporter Gene HAK5 in Response to Low Potassium Stress.
    Plant Cell, 2016. 28(12): p. 3005-3019
    [PMID:27895227]
  9. Promchuea S,Zhu Y,Chen Z,Zhang J,Gong Z
    ARF2 coordinates with PLETHORAs and PINs to orchestrate ABA-mediated root meristem activity in Arabidopsis .
    J Integr Plant Biol, 2017. 59(1): p. 30-43
    [PMID:28074634]
  10. Wójcikowska B,Gaj MD
    Expression profiling of AUXIN RESPONSE FACTOR genes during somatic embryogenesis induction in Arabidopsis.
    Plant Cell Rep., 2017. 36(6): p. 843-858
    [PMID:28255787]
  11. Sanz-Fernández M, et al.
    Screening Arabidopsis mutants in genes useful for phytoremediation.
    J. Hazard. Mater., 2017. 335: p. 143-151
    [PMID:28441590]
  12. Zhang M,Hu X,Zhu M,Xu M,Wang L
    Transcription factors NF-YA2 and NF-YA10 regulate leaf growth via auxin signaling in Arabidopsis.
    Sci Rep, 2017. 7(1): p. 1395
    [PMID:28469131]
  13. Guan C, et al.
    Spatial Auxin Signaling Controls Leaf Flattening in Arabidopsis.
    Curr. Biol., 2017. 27(19): p. 2940-2950.e4
    [PMID:28943086]
  14. Liu Z, et al.
    ARF2-ARF4 and ARF5 are Essential for Female and Male Gametophyte Development in Arabidopsis.
    Plant Cell Physiol., 2018. 59(1): p. 179-189
    [PMID:29145642]
  15. Sarkar Das S, et al.
    Expression dynamics of miRNAs and their targets in seed germination conditions reveals miRNA-ta-siRNA crosstalk as regulator of seed germination.
    Sci Rep, 2018. 8(1): p. 1233
    [PMID:29352229]