PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

GSBRNA2T00131278001

Common Name

GSBRNA2T00131278001

Organism

Brassica napus

Taxonomic ID

3708

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica

Family

bHLH

Protein Properties

Length: 580aa MW: 63349.5 Da PI: 5.0408

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
GSBRNA2T00131278001	genome	Genoscope	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	39.5	1e-12	408	453	4	54
HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 +h e+Er+RR+++N++f Lr ++P+ K++Ka+ L A+ YI++L GSBRNA2T00131278001 408 NHVEAERQRREKLNQRFYSLRAVVPNV-----SKMDKASLLGDAISYINEL 453 799*********************6.....5*************998 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF14215	1.3E-56	62	249	IPR025610	Transcription factor MYC/MYB N-terminal
PROSITE profile	PS50888	17.282	404	453	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	2.60E-14	407	458	No hit	No description
SuperFamily	SSF47459	1.27E-18	407	474	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	4.0E-19	408	473	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	3.7E-10	408	453	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	8.3E-17	410	459	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 580 aa Download sequence Send to blast
MSSTNVQLTD HHLNQSTNGT NLWSTTEDNA SVMEPLIGSE HSSLWPQPPL TPPPPHVTED 60 TLQQRLQALI EGARESWTYA VFWQLSHDFA GEDISNTAAL LSWGDGYYKG EEERKSRKRK 120 PNPVSAAEQE HRKRVIRELN SLISGGGGGG GTAGDEDVSD TEWFFLVSMT QSFANGSGLP 180 GRAFSSSRTI WLSGSNALAG SSCERARQGQ VYGLETMVCI PTQNGVVELG SLEIIHQSSE 240 LVDKVNSFFS FNGGGGGGES GSWAFNLNPD QGENDPATWI NEPNVTGIEP VLGAPATSNS 300 DSQTASKLCN GSSVEHPKQQ QNPQISSSGF VEGDSNKKKR CLVSDKEEEM LSFTSVLPLP 360 TKSNDSNRSD LEASVVKEAE SGRIAAEPEK KPRKRGRKPA NGREEPLNHV EAERQRREKL 420 NQRFYSLRAV VPNVSKMDKA SLLGDAISYI NELKAKLQKA EADKEELQKQ IDGMSKEVGD 480 GNVKSSVKDQ KCLEQDSGVS VEVEIDVKII GWDAMIRIQC GKKDHPGAKF MEALKELELE 540 VNHASLSVVN EFMIQQATVK MGNQFFTQDQ LKAALMERV*

Sequence ? help Back to Top

Protein Sequence Length: 580 aa Download sequence Send to blast

MSSTNVQLTD HHLNQSTNGT NLWSTTEDNA SVMEPLIGSE HSSLWPQPPL TPPPPHVTED  60
TLQQRLQALI EGARESWTYA VFWQLSHDFA GEDISNTAAL LSWGDGYYKG EEERKSRKRK  120
PNPVSAAEQE HRKRVIRELN SLISGGGGGG GTAGDEDVSD TEWFFLVSMT QSFANGSGLP  180
GRAFSSSRTI WLSGSNALAG SSCERARQGQ VYGLETMVCI PTQNGVVELG SLEIIHQSSE  240
LVDKVNSFFS FNGGGGGGES GSWAFNLNPD QGENDPATWI NEPNVTGIEP VLGAPATSNS  300
DSQTASKLCN GSSVEHPKQQ QNPQISSSGF VEGDSNKKKR CLVSDKEEEM LSFTSVLPLP  360
TKSNDSNRSD LEASVVKEAE SGRIAAEPEK KPRKRGRKPA NGREEPLNHV EAERQRREKL  420
NQRFYSLRAV VPNVSKMDKA SLLGDAISYI NELKAKLQKA EADKEELQKQ IDGMSKEVGD  480
GNVKSSVKDQ KCLEQDSGVS VEVEIDVKII GWDAMIRIQC GKKDHPGAKF MEALKELELE  540
VNHASLSVVN EFMIQQATVK MGNQFFTQDQ LKAALMERV*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
4rqw_A	7e-85	55	252	2	195	Transcription factor MYC3
4rqw_B	7e-85	55	252	2	195	Transcription factor MYC3
4rru_A	8e-85	25	245	8	227	Transcription factor MYC3
4rs9_A	7e-85	55	252	2	195	Transcription factor MYC3
4ywc_A	8e-85	25	245	8	227	Transcription factor MYC3
4ywc_B	8e-85	25	245	8	227	Transcription factor MYC3
4yz6_A	7e-85	55	252	2	195	Transcription factor MYC3
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Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	389	397	KKPRKRGRK

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Expressed constitutively at low levels. Preferentially expressed in vascular tissues. {ECO:0000269\|PubMed:12509522, ECO:0000269\|PubMed:21335373}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor involved in jasmonic acid (JA) gene regulation. With MYC2 and MYC3, controls additively subsets of JA-dependent responses. Can form complexes with all known glucosinolate-related MYBs to regulate glucosinolate biosynthesis. Binds to the G-box (5'-CACGTG-3') of promoters. Activates multiple TIFY/JAZ promoters. {ECO:0000269\|PubMed:21321051, ECO:0000269\|PubMed:21335373, ECO:0000269\|PubMed:23943862}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	GSBRNA2T00131278001

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By UV treatment. Not induced by jasmonic acid. {ECO:0000269\|PubMed:12679534, ECO:0000269\|PubMed:21335373}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AC183492	0.0	AC183492.1 Brassica oleracea Contig G, complete sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_013723448.1	0.0	transcription factor MYC4
Swissprot	O49687	0.0	MYC4_ARATH; Transcription factor MYC4
TrEMBL	A0A078I392	0.0	A0A078I392_BRANA; BnaC01g10420D protein
STRING	Bo1g017990.1	0.0	(Brassica oleracea)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM1265	28	96

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G17880.1	0.0	bHLH family protein

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Chico JM, et al. Repression of Jasmonate-Dependent Defenses by Shade Involves Differential Regulation of Protein Stability of MYC Transcription Factors and Their JAZ Repressors in Arabidopsis. Plant Cell, 2014. 26(5): p. 1967-1980 [PMID:24824488] Chalhoub B, et al. Plant genetics. Early allopolyploid evolution in the post-Neolithic Brassica napus oilseed genome. Science, 2014. 345(6199): p. 950-3 [PMID:25146293] Gasperini D, et al. Multilayered Organization of Jasmonate Signalling in the Regulation of Root Growth. PLoS Genet., 2015. 11(6): p. e1005300 [PMID:26070206] Qi T, et al. Regulation of Jasmonate-Induced Leaf Senescence by Antagonism between bHLH Subgroup IIIe and IIId Factors in Arabidopsis. Plant Cell, 2015. 27(6): p. 1634-49 [PMID:26071420] de Torres Zabala M, et al. Novel JAZ co-operativity and unexpected JA dynamics underpin Arabidopsis defence responses to Pseudomonas syringae infection. New Phytol., 2016. 209(3): p. 1120-34 [PMID:26428397] Yu J, et al. JAZ7 negatively regulates dark-induced leaf senescence in Arabidopsis. J. Exp. Bot., 2016. 67(3): p. 751-62 [PMID:26547795] Chen X,Huang H,Qi T,Liu B,Song S New perspective of the bHLH-MYB complex in jasmonate-regulated plant fertility in arabidopsis. Plant Signal Behav, 2016. 11(2): p. e1135280 [PMID:26829586] Schmiesing A,Emonet A,Gouhier-Darimont C,Reymond P Arabidopsis MYC Transcription Factors Are the Target of Hormonal Salicylic Acid/Jasmonic Acid Cross Talk in Response to Pieris brassicae Egg Extract. Plant Physiol., 2016. 170(4): p. 2432-43 [PMID:26884488] Thatcher LF, et al. Characterization of a JAZ7 activation-tagged Arabidopsis mutant with increased susceptibility to the fungal pathogen Fusarium oxysporum. J. Exp. Bot., 2016. 67(8): p. 2367-86 [PMID:26896849] Gao C, et al. MYC2, MYC3, and MYC4 function redundantly in seed storage protein accumulation in Arabidopsis. Plant Physiol. Biochem., 2016. 108: p. 63-70 [PMID:27415132] Gimenez-Ibanez S, et al. JAZ2 controls stomata dynamics during bacterial invasion. New Phytol., 2017. 213(3): p. 1378-1392 [PMID:28005270] Lian TF,Xu YP,Li LF,Su XD Crystal Structure of Tetrameric Arabidopsis MYC2 Reveals the Mechanism of Enhanced Interaction with DNA. Cell Rep, 2017. 19(7): p. 1334-1342 [PMID:28514654] Wang H, et al. The bHLH Transcription Factors MYC2, MYC3, and MYC4 Are Required for Jasmonate-Mediated Inhibition of Flowering in Arabidopsis. Mol Plant, 2017. 10(11): p. 1461-1464 [PMID:28827172] Song S, et al. MYC5 is Involved in Jasmonate-Regulated Plant Growth, Leaf Senescence and Defense Responses. Plant Cell Physiol., 2017. 58(10): p. 1752-1763 [PMID:29017003] Li B, et al. Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis. Plant Cell, 2018. 30(1): p. 178-195 [PMID:29317470] Han X, et al. Jasmonate Negatively Regulates Stomatal Development in Arabidopsis Cotyledons. Plant Physiol., 2018. 176(4): p. 2871-2885 [PMID:29496884]