PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | GSBRNA2T00077252001 | ||||||||
Common Name | GSBRNA2T00077252001 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica
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Family | E2F/DP | ||||||||
Protein Properties | Length: 490aa MW: 53132 Da PI: 4.611 | ||||||||
Description | E2F/DP family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | E2F_TDP | 82.4 | 3.7e-26 | 168 | 233 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL+llt+kf++l++++++g+++ln++a++L +v ++RRiYDi+NVLe+++liek kn+i wkg GSBRNA2T00077252001 168 RYDSSLGLLTRKFVNLIKQAKDGMLDLNKAAETL---EV--QKRRIYDITNVLEGIDLIEKPFKNQILWKG 233 6899******************************...99..****************************98 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Gene3D | G3DSA:1.10.10.10 | 7.0E-28 | 164 | 235 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 2.7E-32 | 168 | 233 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
SuperFamily | SSF46785 | 2.31E-16 | 168 | 231 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
Pfam | PF02319 | 1.0E-22 | 170 | 233 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
CDD | cd14660 | 8.55E-47 | 246 | 350 | No hit | No description |
SuperFamily | SSF144074 | 1.99E-31 | 246 | 350 | No hit | No description |
Pfam | PF16421 | 1.1E-31 | 249 | 348 | IPR032198 | E2F transcription factor, CC-MB domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0006355 | Biological Process | regulation of transcription, DNA-templated | ||||
GO:0005634 | Cellular Component | nucleus | ||||
GO:0005667 | Cellular Component | transcription factor complex | ||||
GO:0003677 | Molecular Function | DNA binding | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 490 aa Download sequence Send to blast |
MSGGARSSPG PSQPPPPHHP PSSPSPSSSL PVVPPIRRNL AFASTKPPFS PSDYHRFAPS 60 HLTDNDKSLV NVCELVDRED DDVVVHRSPS RKRKTTTDVV AATSDSNGLT SSGFSTLSNS 120 PCKTPVSAKG GRVNTKSKAK GSQSIPQTPI SNAVVGSPAT LTPSGSCRYD SSLGLLTRKF 180 VNLIKQAKDG MLDLNKAAET LEVQKRRIYD ITNVLEGIDL IEKPFKNQIL WKGLDTSGPG 240 DVDADVSVLQ AEIENFSLEE QALDNEIRET EERLRELSEN EKNQKWLFVT EEDIKSLPGF 300 QNQTLIAVKA PHGTTLEVPD PDEAVDIPQR RYRIILRSTM GPIDVYLVSE FEKKFEDTNG 360 TATPPPPACL PIASCSGSSE NHEIEALTVD NKGTANEHQA SQDHAHAQPG DTSDLNHLQE 420 QVGGMLKITP SDVENDDTDY WLLSNADISM TDIWKTDSGI DWDYEIADVS TPPPVMGEIA 480 PTGIDSTPR* |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
1cf7_A | 7e-23 | 163 | 234 | 2 | 74 | PROTEIN (TRANSCRIPTION FACTOR E2F-4) |
Search in ModeBase |
Nucleic Localization Signal ? help Back to Top | |||
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No. | Start | End | Sequence |
1 | 89 | 94 | SRKRKT |
Expression -- Description ? help Back to Top | ||||||
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Source | Description | |||||
Uniprot | DEVELOPMENTAL STAGE: Expressed in a cell cycle-dependent manner. Most abundant in early S phase. Decreased expression during the passage into G2. {ECO:0000269|PubMed:11108847, ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543}. | |||||
Uniprot | TISSUE SPECIFICITY: Highly expressed in the shoot apical meristem, emerging leaf primordia, and vascular tissues of young leaf primordia. Expressed in flowers, in epidermis and cortex of hypocotyls, and at lower levels in leaves. {ECO:0000269|PubMed:11108847, ECO:0000269|PubMed:11889041}. |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}. |
Cis-element ? help Back to Top | |
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Source | Link |
PlantRegMap | GSBRNA2T00077252001 |
Regulation -- PlantRegMap ? help Back to Top | ||||||
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Source | Upstream Regulator | Target Gene | ||||
PlantRegMap | Retrieve | - |
Annotation -- Nucleotide ? help Back to Top | ||||||
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Source | Hit ID | E-value | Description | |||
GenBank | JN942984 | 0.0 | JN942984.1 Brassica juncea E2F transcription factor (E2Fa) mRNA, partial cds. |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_009141554.1 | 0.0 | PREDICTED: transcription factor E2FA | ||||
Refseq | XP_022574291.1 | 0.0 | transcription factor E2FA-like isoform X1 | ||||
Swissprot | Q9FNY0 | 0.0 | E2FA_ARATH; Transcription factor E2FA | ||||
TrEMBL | A0A078HYU5 | 0.0 | A0A078HYU5_BRANA; BnaAnng07700D protein | ||||
TrEMBL | A0A3P6CQQ4 | 0.0 | A0A3P6CQQ4_BRACM; Uncharacterized protein | ||||
STRING | Bra017268.1-P | 0.0 | (Brassica rapa) |
Orthologous Group ? help Back to Top | |||
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Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Malvids | OGEM808 | 28 | 121 |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT2G36010.1 | 0.0 | E2F transcription factor 3 |
Publications ? help Back to Top | |||
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