PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID GSBRNA2T00057746001
Common NameGSBRNA2T00057746001
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica
Family MYB
Protein Properties Length: 201aa    MW: 22927.8 Da    PI: 10.0697
Description MYB family protein
Gene Model
Gene Model ID Type Source Coding Sequence
GSBRNA2T00057746001genomeGenoscopeView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding521.6e-161764148
                         TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS
      Myb_DNA-binding  1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48
                         +g WT eEd +l d+v  +G+g+W++I r+ g++R++k+c++rw +yl
  GSBRNA2T00057746001 17 KGLWTVEEDSILRDYVLTHGKGQWNRIVRKTGLKRCGKSCRLRWINYL 64
                         678*******************************************97 PP

2Myb_DNA-binding60.14.8e-1970115148
                          TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS
      Myb_DNA-binding   1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 
                          +g++T++E++l+++++k+lG++ W++Ia++++ gRt++q+k++w ++l
  GSBRNA2T00057746001  70 KGNFTEQEEDLIIRLHKLLGNR-WSLIAKRVP-GRTDNQVKNHWSTHL 115
                          79********************.*********.***********9886 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5129416.4021264IPR017930Myb domain
SuperFamilySSF466892.13E-3015111IPR009057Homeodomain-like
SMARTSM007172.8E-131666IPR001005SANT/Myb domain
PfamPF002494.6E-141764IPR001005SANT/Myb domain
Gene3DG3DSA:1.10.10.601.9E-231871IPR009057Homeodomain-like
CDDcd001673.22E-102064No hitNo description
PROSITE profilePS5129427.18365119IPR017930Myb domain
SMARTSM007175.2E-1869117IPR001005SANT/Myb domain
PfamPF002498.5E-1870115IPR001005SANT/Myb domain
Gene3DG3DSA:1.10.10.606.5E-2672118IPR009057Homeodomain-like
CDDcd001675.55E-1372115No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 201 aa     Download sequence    Send to blast
MRTRRRTEEE NHQEYKKGLW TVEEDSILRD YVLTHGKGQW NRIVRKTGLK RCGKSCRLRW  60
INYLSPNVNK GNFTEQEEDL IIRLHKLLGN RWSLIAKRVP GRTDNQVKNH WSTHLSKKNR  120
RGLSSAVKTT GEENYPPSLL ITAATASGHH QQDKICDKSF EGLVSASNGN KQKADLTHTN  180
DLNESFAMMD FASGDTGYCL *
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1a5j_A1e-26171187107B-MYB
Search in ModeBase
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Ubiquitous in young leaves primordia. Becomes more prominent in developing trichome cells but disappears progressively when trichomes begin to initiate branches. {ECO:0000269|PubMed:15728674}.
UniprotTISSUE SPECIFICITY: Expressed in leaves, stems and flowers (PubMed:11437443). Expressed in trichome cells and in leaf primordia (PubMed:9625690). {ECO:0000269|PubMed:11437443, ECO:0000269|PubMed:9625690}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator, when associated with BHLH2/EGL3/MYC146 or BHLH12/MYC1. Involved in epidermal cell fate specification in leaves. Together with TTG1 and GL3, promotes trichome formation and endoreplication. Regulates the production of a signal that induces hair (trichome) precursor cells on leaf primordia to differentiate. Binds to the WER-binding sites (WBS) promoter regions and activates the transcription of target genes (By similarity). {ECO:0000250, ECO:0000269|PubMed:11063707, ECO:0000269|PubMed:12356720, ECO:0000269|PubMed:15361138, ECO:0000269|PubMed:15728674, ECO:0000269|PubMed:9625690}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapGSBRNA2T00057746001
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated by gibberellins (PubMed:9625690). May be regulated by GEBP and GEBP-like proteins (PubMed:12535344). {ECO:0000269|PubMed:12535344, ECO:0000269|PubMed:9625690}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankKF1882090.0KF188209.1 Brassica villosa BVGL1 (BVGL1) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_013597086.11e-133PREDICTED: trichome differentiation protein GL1
SwissprotP279003e-98GL1_ARATH; Trichome differentiation protein GL1
TrEMBLA0A078JNM21e-148A0A078JNM2_BRANA; BnaCnng52970D protein
STRINGBo7g090950.11e-133(Brassica oleracea)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM4282646
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G27920.11e-100myb domain protein 0
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Nayidu NK, et al.
    Comparison of five major trichome regulatory genes in Brassica villosa with orthologues within the Brassicaceae.
    PLoS ONE, 2014. 9(4): p. e95877
    [PMID:24755905]
  3. Chalhoub B, et al.
    Plant genetics. Early allopolyploid evolution in the post-Neolithic Brassica napus oilseed genome.
    Science, 2014. 345(6199): p. 950-3
    [PMID:25146293]
  4. Sun L, et al.
    GLABROUS INFLORESCENCE STEMS3 (GIS3) regulates trichome initiation and development in Arabidopsis.
    New Phytol., 2015. 206(1): p. 220-30
    [PMID:25640859]
  5. Yu D, et al.
    RPN1a, a subunit of the 26S proteasome, controls trichome development in Arabidopsis.
    Plant Physiol. Biochem., 2015. 88: p. 82-8
    [PMID:25676129]
  6. Huang M,Hu Y,Liu X,Li Y,Hou X
    Arabidopsis LEAFY COTYLEDON1 controls cell fate determination during post-embryonic development.
    Front Plant Sci, 2015. 6: p. 955
    [PMID:26579186]
  7. Dai X, et al.
    A single amino acid substitution in the R3 domain of GLABRA1 leads to inhibition of trichome formation in Arabidopsis without affecting its interaction with GLABRA3.
    Plant Cell Environ., 2016. 39(4): p. 897-907
    [PMID:26667588]
  8. Zheng K, et al.
    Ectopic expression of R3 MYB transcription factor gene OsTCL1 in Arabidopsis, but not rice, affects trichome and root hair formation.
    Sci Rep, 2016. 6: p. 19254
    [PMID:26758286]
  9. Li Y, et al.
    Two IIIf Clade-bHLHs from Freesia hybrida Play Divergent Roles in Flavonoid Biosynthesis and Trichome Formation when Ectopically Expressed in Arabidopsis.
    Sci Rep, 2016. 6: p. 30514
    [PMID:27465838]
  10. Hegebarth D,Buschhaus C,Wu M,Bird D,Jetter R
    The composition of surface wax on trichomes of Arabidopsis thaliana differs from wax on other epidermal cells.
    Plant J., 2016. 88(5): p. 762-774
    [PMID:27496682]
  11. Busta L,Hegebarth D,Kroc E,Jetter R
    Changes in cuticular wax coverage and composition on developing Arabidopsis leaves are influenced by wax biosynthesis gene expression levels and trichome density.
    Planta, 2017. 245(2): p. 297-311
    [PMID:27730411]
  12. Maxwell DJ,Partridge JC,Roberts NW,Boonham N,Foster GD
    The effects of surface structure mutations in Arabidopsis thaliana on the polarization of reflections from virus-infected leaves.
    PLoS ONE, 2017. 12(3): p. e0174014
    [PMID:28346494]
  13. GarcĂ­a-Cano E,Hak H,Magori S,Lazarowitz SG,Citovsky V
    The Agrobacterium F-Box Protein Effector VirF Destabilizes the Arabidopsis GLABROUS1 Enhancer/Binding Protein-Like Transcription Factor VFP4, a Transcriptional Activator of Defense Response Genes.
    Mol. Plant Microbe Interact., 2018. 31(5): p. 576-586
    [PMID:29264953]
  14. Kim SY,Hyoung S,So WM,Shin JS
    The novel transcription factor TRP interacts with ZFP5, a trichome initiation-related transcription factor, and negatively regulates trichome initiation through gibberellic acid signaling.
    Plant Mol. Biol., 2018. 96(3): p. 315-326
    [PMID:29335898]