PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID GSBRNA2T00049089001
Common NameGSBRNA2T00049089001
Organism
Brassica napus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica
Family HD-ZIP
Protein Properties Length: 711aa    MW: 77592.4 Da    PI: 6.6459
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
GSBRNA2T00049089001genomeGenoscopeView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox59.55.3e-193590156
                         TT--SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS
             Homeobox  1 rrkRttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56
                         +++ +++t++q+++Le+ F+++++p+ ++r  L+k+lgL  rq+k+WFqNrR++ k
  GSBRNA2T00049089001 35 KKRYHRHTAQQIQRLESSFRECPHPDDKQRNLLSKELGLAPRQIKFWFQNRRTQLK 90
                         688999**********************************************9877 PP
2START158.64.7e-502244452206
                          HHHHHHHHHHHHHHHC-TT-EEEE...EXCCTTEEEEEEESSS.......SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-S....E CS
                START   2 laeeaaqelvkkalaeepgWvkss...esengdevlqkfeeskv......dsgealrasgvvdmvlallveellddkeqWdetla....k 78 
                          +a++a+qel++++  +ep+W+ s    e +n   +   f++s +       ++ea+r sg+v+m+++ lv  ++d++ +W e ++    +
  GSBRNA2T00049089001 224 IALTAMQELLRLVHTNEPLWSGSDgcgEVLNLGSYENVFPRSSNrgknhnVRIEASRSSGIVFMNAMSLVDMFMDSA-KWAELFPsivaA 312
                          6899**********************9667777666667666667778889**************************.*******99999 PP

                          EEEEEEECTT.......EEEEEEEEXXTTXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--.-TTSEE-EESSEEEEEEEECTC CS
                START  79 aetlevissg.......galqlmvaelqalsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppesssvvRaellpSgiliepksng 160
                           +tl+v+ssg       gal+lm+ e+ +lsplv+ R+f  +Ry++q ++g+w++v vS   +q+++ +s++ R   +pSg+li++++ng
  GSBRNA2T00049089001 313 SKTLAVVSSGmgggtheGALHLMYEEMEVLSPLVAtREFCELRYCQQIEQGSWIVVNVSYHLPQFVS-HSHSYR---FPSGCLIQDMPNG 398
                          *******************************************************************.999999...************* PP

                          EEEEEEEE-EE--SSXX.HHHHHHHHHHHHHHHHHHHHHHTXXXXXX CS
                START 161 hskvtwvehvdlkgrlp.hwllrslvksglaegaktwvatlqrqcek 206
                          +skvtwveh++ +++ p  +++r +v++g+a+ga +wv tlqr ce+
  GSBRNA2T00049089001 399 YSKVTWVEHTETEEKEPvNEMYREMVHKGIAFGAERWVTTLQRMCER 445
                          *********************************************97 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.602.7E-202394IPR009057Homeodomain-like
SuperFamilySSF466897.94E-192996IPR009057Homeodomain-like
PROSITE profilePS5007117.5243292IPR001356Homeobox domain
SMARTSM003891.2E-173396IPR001356Homeobox domain
PfamPF000461.8E-163590IPR001356Homeobox domain
CDDcd000861.90E-183593No hitNo description
PROSITE patternPS0002706790IPR017970Homeobox, conserved site
PROSITE profilePS5084848.543214448IPR002913START domain
SuperFamilySSF559611.1E-32215447No hitNo description
CDDcd088752.29E-101218444No hitNo description
SMARTSM002341.5E-39223445IPR002913START domain
PfamPF018522.8E-43224445IPR002913START domain
Gene3DG3DSA:3.30.530.201.1E-7276445IPR023393START-like domain
SuperFamilySSF559619.67E-19464697No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0008289Molecular Functionlipid binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 711 aa     Download sequence    Send to blast
MSFVVGGSGS GGGDGGDGDG GGRQRHDASE TDRKKKRYHR HTAQQIQRLE SSFRECPHPD  60
DKQRNLLSKE LGLAPRQIKF WFQNRRTQLK AQHERADNSA LKAENDKIRC ENIAIREALK  120
HAICPNCGGP PVSEDPYLDE QKLRMENAHL REELERMSTV ASKYMGRPIS SHISTLHPMH  180
ISPLDLSMTS LAGGPSLDFD LLPGSSMSSN FAVSDMDKPI MNDIALTAMQ ELLRLVHTNE  240
PLWSGSDGCG EVLNLGSYEN VFPRSSNRGK NHNVRIEASR SSGIVFMNAM SLVDMFMDSA  300
KWAELFPSIV AASKTLAVVS SGMGGGTHEG ALHLMYEEME VLSPLVATRE FCELRYCQQI  360
EQGSWIVVNV SYHLPQFVSH SHSYRFPSGC LIQDMPNGYS KVTWVEHTET EEKEPVNEMY  420
REMVHKGIAF GAERWVTTLQ RMCERYASLL APAASSLVLV IPSPEGKRSM MRLAHRMVSN  480
YCISVSRSNN TRSTVVAELN EVGVRVTAHK SPEPNGTILS AATTFWLPNS PQNVFNFLKD  540
ERTRPQWDVL SNSNAVQEVA HIANGSHPGC CISVLRASSA SQSNNMLILQ ETSIDSSGAL  600
VVYSPVDLSA LNIAMNGDDT SYIPILSSGF AISPDGNRNS PSAEQGGASS SSGYGGGGSL  660
ITVGFQITVS NLPSAKLNME SVETVNNLIG TTVHQIKTGL NNFPSASTTV *
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: During embryo development, expressed in all cells at the 4- and 16-cell embryo stages. Expression is restricted to the protoderm from the globular stage onward. {ECO:0000269|PubMed:25564655}.
UniprotTISSUE SPECIFICITY: Expressed in apical meristems and young epidermal tissue including trichomes and stipules. Expressed in lateral root tips, the L1 layer of apical inflorescence meristems and early flower primordia, carpel and petal epidermis, stigma papillae, ovule primordia, nucellus and embryo. {ECO:0000269|PubMed:16778018}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor which acts as positive regulator of drought stress tolerance. Can transactivate CIPK3, NCED3 and ERECTA (PubMed:18451323). Transactivates several cell-wall-loosening protein genes by directly binding to HD motifs in their promoters. These target genes play important roles in coordinating cell-wall extensibility with root development and growth (PubMed:24821957). Transactivates CYP74A/AOS, AOC3, OPR3 and 4CLL5/OPCL1 genes by directly binding to HD motifs in their promoters. These target genes are involved in jasmonate (JA) biosynthesis, and JA signaling affects root architecture by activating auxin signaling, which promotes lateral root formation (PubMed:25752924). Acts as negative regulator of trichome branching (PubMed:16778018, PubMed:24824485). Required for the establishment of giant cell identity on the abaxial side of sepals (PubMed:23095885). May regulate cell differentiation and proliferation during root and shoot meristem development (PubMed:25564655). {ECO:0000269|PubMed:16778018, ECO:0000269|PubMed:18451323, ECO:0000269|PubMed:23095885, ECO:0000269|PubMed:24821957, ECO:0000269|PubMed:24824485, ECO:0000269|PubMed:25564655, ECO:0000269|PubMed:25752924}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapGSBRNA2T00049089001
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_013699248.10.0homeobox-leucine zipper protein HDG11-like
SwissprotQ9FX310.0HDG11_ARATH; Homeobox-leucine zipper protein HDG11
TrEMBLA0A078FDU60.0A0A078FDU6_BRANA; BnaC06g23610D protein
STRINGBo6g087810.10.0(Brassica oleracea)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM30042665
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G73360.10.0homeodomain GLABROUS 11
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Khosla A, et al.
    HD-Zip Proteins GL2 and HDG11 Have Redundant Functions in Arabidopsis Trichomes, and GL2 Activates a Positive Feedback Loop via MYB23.
    Plant Cell, 2014. 26(5): p. 2184-2200
    [PMID:24824485]
  3. Chalhoub B, et al.
    Plant genetics. Early allopolyploid evolution in the post-Neolithic Brassica napus oilseed genome.
    Science, 2014. 345(6199): p. 950-3
    [PMID:25146293]
  4. Horstman A, et al.
    AIL and HDG proteins act antagonistically to control cell proliferation.
    Development, 2015. 142(3): p. 454-64
    [PMID:25564655]
  5. Cai XT,Xu P,Wang Y,Xiang CB
    Activated expression of AtEDT1/HDG11 promotes lateral root formation in Arabidopsis mutant edt1 by upregulating jasmonate biosynthesis.
    J Integr Plant Biol, 2015. 57(12): p. 1017-30
    [PMID:25752924]
  6. Yu LH, et al.
    Arabidopsis EDT1/HDG11 improves drought and salt tolerance in cotton and poplar and increases cotton yield in the field.
    Plant Biotechnol. J., 2016. 14(1): p. 72-84
    [PMID:25879154]
  7. Zhu Z, et al.
    Overexpression of AtEDT1/HDG11 in Chinese Kale (Brassica oleracea var. alboglabra) Enhances Drought and Osmotic Stress Tolerance.
    Front Plant Sci, 2016. 7: p. 1285
    [PMID:27625663]
  8. Liu Y, et al.
    Overexpression of AtEDT1 promotes root elongation and affects medicinal secondary metabolite biosynthesis in roots of transgenic Salvia miltiorrhiza.
    Protoplasma, 2017. 254(4): p. 1617-1625
    [PMID:27915455]
  9. Ueda M, et al.
    Transcriptional integration of paternal and maternal factors in the Arabidopsis zygote.
    Genes Dev., 2017. 31(6): p. 617-627
    [PMID:28404632]
  10. Lung SC, et al.
    Arabidopsis ACYL-COA-BINDING PROTEIN1 interacts with STEROL C4-METHYL OXIDASE1-2 to modulate gene expression of homeodomain-leucine zipper IV transcription factors.
    New Phytol., 2018. 218(1): p. 183-200
    [PMID:29288621]
  11. Zheng G, et al.
    Over-Expression of Arabidopsis EDT1 Gene Confers Drought Tolerance in Alfalfa (Medicago sativa L.).
    Front Plant Sci, 2017. 8: p. 2125
    [PMID:29326737]