PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

GSBRNA2T00016157001

Common Name

GSBRNA2T00016157001

Organism

Brassica napus

Taxonomic ID

3708

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica

Family

BES1

Protein Properties

Length: 387aa MW: 42525.5 Da PI: 9.8471

Description

BES1 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
GSBRNA2T00016157001	genome	Genoscope	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	DUF822	193	1.1e-59	82	221	2	149
DUF822 2 gsgrkptwkErEnnkrRERrRRaiaakiyaGLRaqGnyklpkraDnneVlkALcreAGwvvedDGttyrkgskpleeaeaagssasaspe 91 +++rkp+w+ErEnn+rRER+RRa+aakiy GLRaqGn++lp ++DnneVlkALc eAGwvve+DGttyrkg kpl ++agss++a+ GSBRNA2T00016157001 82 ATRRKPSWRERENNRRRERKRRAVAAKIYNGLRAQGNFNLPRHCDNNEVLKALCSEAGWVVEEDGTTYRKGHKPL-PDDMAGSSSRATAY 170 689**********************************************************************.999******* PP DUF822 92 sslqsslkssalaspvesysaspksssfpspssldsislasaasllpvlsvlslvsss 149 ss++ s ++sp+ sy+asp+sssfpsp d+ +++ +++p+l++ + +ss GSBRNA2T00016157001 171 SSYN----QSPFESPILSYQASPSSSSFPSPRGGDTHNIS---TIFPFLRNGGINPSS 221 99....889*************************9995...899999988776665 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF05687	6.1E-57	83	207	IPR008540	BES1/BZR1 plant transcription factor, N-terminal

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated

Sequence ? help Back to Top
Protein Sequence Length: 387 aa Download sequence Send to blast
MKHVTGAQPA QWLEVFAKEM EAGWIRDTSY KTSGVHQYVL AKRILGPNFM VGSEDSEETF 60 GKHQKKNMTS EGAMLTSAAA MATRRKPSWR ERENNRRRER KRRAVAAKIY NGLRAQGNFN 120 LPRHCDNNEV LKALCSEAGW VVEEDGTTYR KGHKPLPDDM AGSSSRATAY SSYNQSPFES 180 PILSYQASPS SSSFPSPRGG DTHNISTIFP FLRNGGINPS SLPPLRISNS APVTPPVSSP 240 TSRNPKPLPT WESLTKQAMA NAARQSVSSF NYPFYAVSAP TSPTHHRQFN APATIPECDE 300 SDSSTTDSGH WISFQKFSQQ QFRGGFAVPP SPTFNLVKPP LPQQLSSNIA AAQEIGSQVK 360 PWEGERIHDV AMEDLELTLG NSKGRS*

Sequence ? help Back to Top

Protein Sequence Length: 387 aa Download sequence Send to blast

MKHVTGAQPA QWLEVFAKEM EAGWIRDTSY KTSGVHQYVL AKRILGPNFM VGSEDSEETF  60
GKHQKKNMTS EGAMLTSAAA MATRRKPSWR ERENNRRRER KRRAVAAKIY NGLRAQGNFN  120
LPRHCDNNEV LKALCSEAGW VVEEDGTTYR KGHKPLPDDM AGSSSRATAY SSYNQSPFES  180
PILSYQASPS SSSFPSPRGG DTHNISTIFP FLRNGGINPS SLPPLRISNS APVTPPVSSP  240
TSRNPKPLPT WESLTKQAMA NAARQSVSSF NYPFYAVSAP TSPTHHRQFN APATIPECDE  300
SDSSTTDSGH WISFQKFSQQ QFRGGFAVPP SPTFNLVKPP LPQQLSSNIA AAQEIGSQVK  360
PWEGERIHDV AMEDLELTLG NSKGRS*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5zd4_A	8e-33	84	166	371	453	Maltose-binding periplasmic protein,Protein BRASSINAZOLE-RESISTANT 1
5zd4_B	8e-33	84	166	371	453	Maltose-binding periplasmic protein,Protein BRASSINAZOLE-RESISTANT 1
5zd4_C	8e-33	84	166	371	453	Maltose-binding periplasmic protein,Protein BRASSINAZOLE-RESISTANT 1
5zd4_D	8e-33	84	166	371	453	Maltose-binding periplasmic protein,Protein BRASSINAZOLE-RESISTANT 1
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	83	102	RRKPSWRERENNRRRERKRR

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
Bna.24085	0.0	leaf

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Ubiquitously expressed in cotyledons, leaves, hypocotyls and roots. {ECO:0000269\|PubMed:12007405}.

Functional Description ? help Back to Top
Source	Description
UniProt	Positive regulator of brassinosteroid (BR) signaling. Transcription factor that activates target gene expression by binding specifically to the DNA sequence 5'-CANNTG-3'(E box) through its N-terminal domain. Can bind individually to the promoter as a homodimer or synergistically as a heterodimer with BIM1, BIM2 or BIM3. The C-terminal domain is probably involved in transcriptional activation (PubMed:12007405, PubMed:15680330, PubMed:18467490, PubMed:19170933). Recruits the transcription elongation factor IWS1 to control BR-regulated gene expression (PubMed:20139304). Forms a trimeric complex with IWS1 and ASHH2/SDG8 to regulate BR-regulated gene expression (PubMed:24838002). Promotes quiescent center (QC) self-renewal by cell divisions in the primary root. Binds to the E-boxes of the BRAVO promoter to repress its expression (PubMed:24981610). {ECO:0000269\|PubMed:12007405, ECO:0000269\|PubMed:15680330, ECO:0000269\|PubMed:18467490, ECO:0000269\|PubMed:19170933, ECO:0000269\|PubMed:20139304, ECO:0000269\|PubMed:24838002, ECO:0000269\|PubMed:24981610}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	GSBRNA2T00016157001

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009117543.1	0.0	PREDICTED: protein BRASSINAZOLE-RESISTANT 2-like
Refseq	XP_009117544.1	0.0	PREDICTED: protein BRASSINAZOLE-RESISTANT 2-like
Refseq	XP_009117545.1	0.0	PREDICTED: protein BRASSINAZOLE-RESISTANT 2-like
Refseq	XP_013664647.1	0.0	protein BRASSINAZOLE-RESISTANT 2-like
Swissprot	Q9LN63	1e-164	BZR2_ARATH; Protein BRASSINAZOLE-RESISTANT 2
TrEMBL	A0A078G5C8	0.0	A0A078G5C8_BRANA; BnaA09g44210D protein
TrEMBL	A0A3P5Y899	0.0	A0A3P5Y899_BRACM; Uncharacterized protein
TrEMBL	M4EQK6	0.0	M4EQK6_BRARP; Uncharacterized protein
STRING	Bra031077.1-P	0.0	(Brassica rapa)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM2472	27	72

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G19350.3	1e-141	BES1 family protein

Publications ? help Back to Top
Chalhoub B, et al. Plant genetics. Early allopolyploid evolution in the post-Neolithic Brassica napus oilseed genome. Science, 2014. 345(6199): p. 950-3 [PMID:25146293] Salazar-Henao JE,Lehner R,Betegón-Putze I,Vilarrasa-Blasi J,Caño-Delgado AI BES1 regulates the localization of the brassinosteroid receptor BRL3 within the provascular tissue of the Arabidopsis primary root. J. Exp. Bot., 2016. 67(17): p. 4951-61 [PMID:27511026] Nolan T, et al. Identification of Brassinosteroid Target Genes by Chromatin Immunoprecipitation Followed by High-Throughput Sequencing (ChIP-seq) and RNA-Sequencing. Methods Mol. Biol., 2017. 1564: p. 63-79 [PMID:28124247] Ye H, et al. RD26 mediates crosstalk between drought and brassinosteroid signalling pathways. Nat Commun, 2017. 8: p. 14573 [PMID:28233777] Nolan TM, et al. Selective Autophagy of BES1 Mediated by DSK2 Balances Plant Growth and Survival. Dev. Cell, 2017. 41(1): p. 33-46.e7 [PMID:28399398] Yang M, et al. SINAT E3 Ligases Control the Light-Mediated Stability of the Brassinosteroid-Activated Transcription Factor BES1 in Arabidopsis. Dev. Cell, 2017. 41(1): p. 47-58.e4 [PMID:28399399] Chen J, et al. Arabidopsis WRKY46, WRKY54, and WRKY70 Transcription Factors Are Involved in Brassinosteroid-Regulated Plant Growth and Drought Responses. Plant Cell, 2017. 29(6): p. 1425-1439 [PMID:28576847] Yang M,Wang X Multiple Ways of BES1/BZR1 Degradation to Decode Distinct Developmental and Environmental Cues in Plants. Mol Plant, 2017. 10(7): p. 915-917 [PMID:28629641] Saito M,Kondo Y,Fukuda H BES1 and BZR1 Redundantly Promote Phloem and Xylem Differentiation. Plant Cell Physiol., 2018. 59(3): p. 590-600 [PMID:29385529] Liang T, et al. UVR8 Interacts with BES1 and BIM1 to Regulate Transcription and Photomorphogenesis in Arabidopsis. Dev. Cell, 2018. 44(4): p. 512-523.e5 [PMID:29398622]