PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | GSBRNA2T00002070001 | ||||||||
Common Name | GSBRNA2T00002070001 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica
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Family | E2F/DP | ||||||||
Protein Properties | Length: 378aa MW: 42468.7 Da PI: 5.5071 | ||||||||
Description | E2F/DP family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | E2F_TDP | 83.6 | 1.5e-26 | 145 | 210 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL+llt+kf++l++++e+g ++ln +a+ L +v ++RRiYDi+NVLe+++liek+ kn+irwkg GSBRNA2T00002070001 145 RYDSSLGLLTKKFVNLIREAEDGSLDLNYCADVL---EV--QKRRIYDITNVLEGVGLIEKTTKNHIRWKG 210 6899******************************...99..****************************98 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Gene3D | G3DSA:1.10.10.10 | 3.4E-28 | 141 | 212 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SuperFamily | SSF46785 | 7.35E-17 | 145 | 208 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 7.3E-33 | 145 | 210 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Pfam | PF02319 | 3.3E-24 | 147 | 210 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
CDD | cd14660 | 1.01E-40 | 221 | 328 | No hit | No description |
SuperFamily | SSF144074 | 1.86E-28 | 222 | 327 | No hit | No description |
Pfam | PF16421 | 7.1E-27 | 226 | 325 | IPR032198 | E2F transcription factor, CC-MB domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0000902 | Biological Process | cell morphogenesis | ||||
GO:0006355 | Biological Process | regulation of transcription, DNA-templated | ||||
GO:0042023 | Biological Process | DNA endoreduplication | ||||
GO:0051782 | Biological Process | negative regulation of cell division | ||||
GO:0005667 | Cellular Component | transcription factor complex | ||||
GO:0005730 | Cellular Component | nucleolus | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding | ||||
GO:0044212 | Molecular Function | transcription regulatory region DNA binding | ||||
GO:0046982 | Molecular Function | protein heterodimerization activity |
Sequence ? help Back to Top |
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Protein Sequence Length: 378 aa Download sequence Send to blast |
MAATSKSGED PSLSYNHRSP FRFELIHSPS PTDPLQSSSS TPSSTNRPLS VPQPLPNAQS 60 PQIQAHWDES FSPITQKLQK SRKNHSISSS SMPGETIDIA KVIVKQESPQ DNIKRGTKSK 120 VTKLSKAVKR EGLQLSGPNG SNNCRYDSSL GLLTKKFVNL IREAEDGSLD LNYCADVLEV 180 QKRRIYDITN VLEGVGLIEK TTKNHIRWKG ADNLGQLELG NQISRLKLEV ESMQSEENRL 240 DDLIRERQEA LRSLEEDEHC KRYMFMTEED ITSLPCFHNQ TLLAIKAPTA SCIEVPDPDE 300 VMSFPQRQYR MVIRSRMGPI DVFLLSKHKG DSSMETDESA VDTSSLKIVT SDTDLKTDYW 360 FESGEEVTLT DLWNNFC* |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
1cf7_A | 4e-24 | 145 | 211 | 7 | 74 | PROTEIN (TRANSCRIPTION FACTOR E2F-4) |
Search in ModeBase |
Expression -- Description ? help Back to Top | ||||||
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Source | Description | |||||
Uniprot | DEVELOPMENTAL STAGE: Expressed in a cell cycle-dependent manner. Not detected at the G1/S transition, but increases during the progression into S phase and peaks after the passage into G2. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:12468727}. | |||||
Uniprot | TISSUE SPECIFICITY: Expressed in meristematic areas, vascular tissues, apical part of the roots, cotyledons, upper region of the hypocotyls, trichomes, young flower buds and pollen grains. {ECO:0000269|PubMed:12468727, ECO:0000269|PubMed:16920782}. |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Involved in transcriptional repression. May act by repressing E2F-regulated genes in mature differentiated cells, but is not an antagonist of E2FA. Restricts cell division and is involved in the coordination between cell proliferation and endoreduplication during development. May play a role during the transition from skotomorphogenesis to photomorphogenesis. Regulated by phosphorylation-dependent proteolysis via the protein-ubiquitin ligase SCF(SKP2A) complex. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12468727, ECO:0000269|PubMed:16920782, ECO:0000269|PubMed:19662336}. |
Binding Motif ? help Back to Top | |||
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Motif ID | Method | Source | Motif file |
MP00190 | DAP | Transfer from AT1G47870 | Download |
Cis-element ? help Back to Top | |
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Source | Link |
PlantRegMap | GSBRNA2T00002070001 |
Regulation -- Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | INDUCTION: Down-regulated by light. {ECO:0000269|PubMed:12468727, ECO:0000269|PubMed:18424613}. |
Regulation -- PlantRegMap ? help Back to Top | ||||||
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Source | Upstream Regulator | Target Gene | ||||
PlantRegMap | Retrieve | Retrieve |
Annotation -- Nucleotide ? help Back to Top | ||||||
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Source | Hit ID | E-value | Description | |||
GenBank | JN942973 | 0.0 | JN942973.1 Brassica juncea E2F transcription factor (E2Fc) mRNA, partial cds. |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_013665644.1 | 0.0 | transcription factor E2FC isoform X1 | ||||
Swissprot | Q9FV70 | 0.0 | E2FC_ARATH; Transcription factor E2FC | ||||
TrEMBL | A0A078FYB3 | 0.0 | A0A078FYB3_BRANA; BnaC08g04110D protein | ||||
STRING | Bo8g016640.1 | 0.0 | (Brassica oleracea) |
Orthologous Group ? help Back to Top | |||
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Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Malvids | OGEM808 | 28 | 121 |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT1G47870.1 | 0.0 | E2F/DP family protein |
Publications ? help Back to Top | |||
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