PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Bradi3g45130.8.p
Common NameBRADI_3g45130, LOC100823596
Organism
Brachypodium distachyon
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Pooideae; Brachypodieae; Brachypodium
Family E2F/DP
Protein Properties Length: 374aa    MW: 41324.1 Da    PI: 4.6497
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Bradi3g45130.8.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP85.15.4e-2755120171
           E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                       r+++sL+llt+kf++ll+++++gi++ln++a++L   +v  ++RRiYDi+NVLe+++liek+ kn+irwkg
  Bradi3g45130.8.p  55 RYDSSLGLLTKKFITLLKQADDGILDLNNAAETL---EV--QKRRIYDITNVLEGIGLIEKTLKNRIRWKG 120
                       6899******************************...99..****************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.102.0E-2853122IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013726.0E-3455120IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467856.61E-1855118IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023193.4E-2457120IPR003316E2F/DP family, winged-helix DNA-binding domain
CDDcd146602.48E-49130236No hitNo description
SuperFamilySSF1440744.18E-34133236No hitNo description
PfamPF164212.0E-33135234IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0008284Biological Processpositive regulation of cell proliferation
GO:0009733Biological Processresponse to auxin
GO:0010090Biological Processtrichome morphogenesis
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0051302Biological Processregulation of cell division
GO:0051446Biological Processpositive regulation of meiotic cell cycle
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0005737Cellular Componentcytoplasm
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 374 aa     Download sequence    Send to blast
MIISPGFTGN KLLTPVSGKA VKTSKSKAKN NKAGPQTPTQ NVGSPLNPAT PGTCRYDSSL  60
GLLTKKFITL LKQADDGILD LNNAAETLEV QKRRIYDITN VLEGIGLIEK TLKNRIRWKG  120
LDDSGVELDN GLSALQAEVE DLNLQEQALD ERISDMREKL RGLTEDENSQ RWLYVTEDDI  180
KGLPCFQNET LIAIKAPHGT TLEVPDPDEA GDYLQRRYRI VLRSTMGPID VYLVSQFDEG  240
FEDLGGAATP PRHTNVPTHR PPEDLHTTNA AQSSKSMDVE HNIQYSQNTP HDPSSAHDFG  300
GMTRIIPSDV NTDADYWLLT EGDVSITDIW KTAQVQWDSD VFLPEDVSTP RAHNQHPVAV  360
GESRMQVQSM DQP*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A1e-2448121274PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapBradi3g45130.8.p
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAJ2385900.0AJ238590.1 Triticum sp. mRNA for E2F protein.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_014755532.10.0transcription factor E2FA isoform X2
SwissprotQ9FNY01e-119E2FA_ARATH; Transcription factor E2FA
TrEMBLA0A0Q3FKI20.0A0A0Q3FKI2_BRADI; Uncharacterized protein
TrEMBLA0A2K2D3B90.0A0A2K2D3B9_BRADI; Uncharacterized protein
STRINGBRADI3G45130.10.0(Brachypodium distachyon)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G36010.11e-117E2F transcription factor 3
Publications ? help Back to Top
  1. Magyar Z, et al.
    Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes.
    EMBO J., 2012. 31(6): p. 1480-93
    [PMID:22307083]