PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Bradi2g23520.1.p

Common Name

BRADI_2g23520, LOC100822537

Organism

Brachypodium distachyon

Taxonomic ID

15368

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Pooideae; Brachypodieae; Brachypodium

Family

bHLH

Protein Properties

Length: 237aa MW: 25706.2 Da PI: 8.4641

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Bradi2g23520.1.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	28.9	2.1e-09	72	119	4	54
HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 ++ rE+ RRdr+N++f+eL +l + + +K +K++iL A + +++L Bradi2g23520.1.p 72 TKACREKLRRDRLNERFNELCAVLEPG---KPPKADKVAILGDAARLLNQL 119 5678********************9...99***********999998 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF47459	2.75E-12	62	134	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profile	PS50888	11.719	68	119	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	8.0E-7	72	119	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	2.62E-7	72	124	No hit	No description
SMART	SM00353	4.9E-7	74	125	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	3.6E-11	75	141	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 237 aa Download sequence Send to blast
MSCGGGQNGW LLDYGLVDEE IQGSDFIYMV DDPAVSSVIL GFDAPRKEDG GGLDNSGAKK 60 RSRPESSAPP GTKACREKLR RDRLNERFNE LCAVLEPGKP PKADKVAILG DAARLLNQLR 120 AEAQKLKKSN ESLQDNIKSL KSEKSELRDE KTKLKAERER LEQMLKGATA AVAAPPQFVP 180 HPAAPPHFHP TAAFAQAGKF VPAYTASYPP PAAFWQWIPP TSLDTSKDPA HWPPVA*

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor. Plays a role in resistance to amide-linked indole-3-acetic acid (IAA) conjugates such as IAA-Leu and IAA-Phe. May regulate gene expression in response to metal homeostasis changes. {ECO:0000269\|PubMed:17028341}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Bradi2g23520.1.p

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_003568328.1	1e-173	transcription factor ILR3
Swissprot	Q9FH37	5e-57	ILR3_ARATH; Transcription factor ILR3
TrEMBL	I1HIU6	1e-172	I1HIU6_BRADI; Uncharacterized protein
STRING	BRADI2G23520.1	1e-173	(Brachypodium distachyon)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP9386	31	36
Representative plant	OGRP755	17	66

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G54680.1	1e-48	bHLH family protein

Link Out ? help Back to Top
Phytozome	Bradi2g23520.1.p
Entrez Gene	100822537

Publications ? help Back to Top
Li X,Zhang H,Ai Q,Liang G,Yu D Two bHLH Transcription Factors, bHLH34 and bHLH104, Regulate Iron Homeostasis in Arabidopsis thaliana. Plant Physiol., 2016. 170(4): p. 2478-93 [PMID:26921305] Aparicio F,Pallás V The coat protein of Alfalfa mosaic virus interacts and interferes with the transcriptional activity of the bHLH transcription factor ILR3 promoting salicylic acid-dependent defence signalling response. Mol. Plant Pathol., 2017. 18(2): p. 173-186 [PMID:26929142] Liang G,Zhang H,Li X,Ai Q,Yu D bHLH transcription factor bHLH115 regulates iron homeostasis in Arabidopsis thaliana. J. Exp. Bot., 2017. 68(7): p. 1743-1755 [PMID:28369511] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470] Li B, et al. Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis. Plant Cell, 2018. 30(1): p. 178-195 [PMID:29317470] Min JH, et al. Arabidopsis Basic Helix-Loop-Helix 34 (bHLH34) Is Involved in Glucose Signaling through Binding to a GAGA Cis-Element. Front Plant Sci, 2017. 8: p. 2100 [PMID:29321786] Samira R, et al. The bHLH transcription factor ILR3 modulates multiple stress responses in Arabidopsis. Plant Mol. Biol., 2018. 97(4-5): p. 297-309 [PMID:29882068]