PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | evm_27.model.AmTr_v1.0_scaffold00220.3 | ||||||||
Common Name | AMTR_s00220p00023690 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; basal Magnoliophyta; Amborellales; Amborellaceae; Amborella
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Family | E2F/DP | ||||||||
Protein Properties | Length: 421aa MW: 46967.9 Da PI: 4.5796 | ||||||||
Description | E2F/DP family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | E2F_TDP | 85.3 | 4.6e-27 | 86 | 151 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL+llt+kf++l++++e gi++lne+a++L +v ++RRiYDi+NVLe+++liek+ kn+irwkg evm_27.model.AmTr_v1.0_scaffold00220.3 86 RYDSSLGLLTKKFITLIKQAEGGILDLNEAADTL---EV--QKRRIYDITNVLEGIGLIEKTLKNRIRWKG 151 6899******************************...99..****************************98 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Gene3D | G3DSA:1.10.10.10 | 1.4E-28 | 84 | 153 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SuperFamily | SSF46785 | 1.27E-17 | 86 | 149 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 4.5E-35 | 86 | 151 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Pfam | PF02319 | 2.7E-24 | 88 | 151 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
SuperFamily | SSF144074 | 4.45E-33 | 165 | 268 | No hit | No description |
CDD | cd14660 | 2.37E-48 | 167 | 268 | No hit | No description |
Pfam | PF16421 | 6.7E-33 | 167 | 266 | IPR032198 | E2F transcription factor, CC-MB domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0000902 | Biological Process | cell morphogenesis | ||||
GO:0006355 | Biological Process | regulation of transcription, DNA-templated | ||||
GO:0042023 | Biological Process | DNA endoreduplication | ||||
GO:0051782 | Biological Process | negative regulation of cell division | ||||
GO:0005667 | Cellular Component | transcription factor complex | ||||
GO:0005730 | Cellular Component | nucleolus | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding | ||||
GO:0044212 | Molecular Function | transcription regulatory region DNA binding | ||||
GO:0046982 | Molecular Function | protein heterodimerization activity |
Sequence ? help Back to Top |
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Protein Sequence Length: 421 aa Download sequence Send to blast |
MGEPQGCVLN QKSEIEDYEV ETSDWTESEG YMEAVNSPVV TPVPGTGGRR YSRAKVSKIR 60 RSIPQSPSLN DSSPSKNTLT PVGTCRYDSS LGLLTKKFIT LIKQAEGGIL DLNEAADTLE 120 VQKRRIYDIT NVLEGIGLIE KTLKNRIRWK GLEESRPGEL INGVAMLQAE VENMSIKEHK 180 LDDSIRDKQE RLRILSEDEN NKKWLYVTEE DIKSLPCFQN ETLIAIKAPH GTTLEVPDPD 240 EAPDYPQRRY QMLLRSTMGP IDVYLVSQFD EKIEDMNNIE SQPIDMIPTS VVSNNSRVQP 300 EFPAMGLLKD MGHVQDGQTT SSSSCNSQDL AGGMMKIVPS YVNLDADYWL SADAGVSMTD 360 MWKSGSSVAV HEDERINLDK YPVADSGVLQ RHIPSSCNHE PKTYVTRLAC WSEEVGAWSM 420 * |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
1cf7_A | 2e-23 | 81 | 152 | 1 | 74 | PROTEIN (TRANSCRIPTION FACTOR E2F-4) |
Search in ModeBase |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Involved in the control of cell-cycle progression from G1 to S phase and from G2 to M phase. Stimulates cell proliferation and delays differentiation. Represses cell enlargement and endoreduplication in auxin-free conditions. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015}. |
Regulation -- Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | INDUCTION: Up-regulated by light and by auxin. May be up-regulated by E2FA. {ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:18424613}. |
Regulation -- PlantRegMap ? help Back to Top | ||||||
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Source | Upstream Regulator | Target Gene | ||||
PlantRegMap | Retrieve | - |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_020518401.1 | 0.0 | transcription factor E2FB | ||||
Swissprot | Q9FV71 | 1e-119 | E2FB_ARATH; Transcription factor E2FB | ||||
TrEMBL | W1NTM7 | 0.0 | W1NTM7_AMBTC; Uncharacterized protein | ||||
STRING | ERM98862 | 0.0 | (Amborella trichopoda) |
Orthologous Group ? help Back to Top | |||
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Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Representative plant | OGRP1225 | 17 | 49 |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT5G22220.2 | 1e-122 | E2F transcription factor 1 |
Link Out ? help Back to Top | |
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Phytozome | evm_27.model.AmTr_v1.0_scaffold00220.3 |
Publications ? help Back to Top | |||
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